1. Articles from Rachel Nolan

    1-3 of 3
    1. Multicenter reliability of semiautomatic retinal layer segmentation using OCT

      Multicenter reliability of semiautomatic retinal layer segmentation using OCT

      Objective To evaluate the inter-rater reliability of semiautomated segmentation of spectral domain optical coherence tomography (OCT) macular volume scans. Methods Macular OCT volume scans of left eyes from 17 subjects (8 patients with MS and 9 healthy controls) were automatically segmented by Heidelberg Eye Explorer (v1.9.3.0) beta-software (Spectralis Viewing Module v6.0.0.7), followed by manual correction by 5 experienced operators from 5 different academic centers. The mean thicknesses within a 6-mm area around the fovea were computed for the retinal nerve fiber layer, ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer, outer ...

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    2. Monitoring the Course of MS With Optical Coherence Tomography

      Monitoring the Course of MS With Optical Coherence Tomography

      Retinae of patients with multiple sclerosis (MS), as part of the central nervous system (CNS), display inflammatory and neurodegenerative changes. There is increasing evidence suggesting that retinal changes, and in particular neurodegeneration, mirror global CNS alterations in MS. Spectral domain optical coherence tomography (SD-OCT) is an inexpensive, rapid, non-invasive, and reproducible imaging technique that generates high-resolution images of tissues such as the retina. An advantage of SD-OCT over magnetic resonance imaging techniques in the assessment of neurodegeneration may be its sensitivity to capture changes at the individual patient level. Several studies demonstrate that changes within the inner retina (primarily as ...

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    3. Utility of optical coherence tomography in the evaluation of monocular visual loss related to retinal ischemia

      Utility of optical coherence tomography in the evaluation of monocular visual loss related to retinal ischemia

      We report four patients with monocular visual loss for whom optical coherence tomography (OCT) was helpful in distinguishing the sequelae of retinal artery occlusion from those of primary optic neuropathy. Determinations of the peripapillary retinal nerve fiber layer (RNFL) thickness as well as macular retinal layer thicknesses and architecture were used. The major findings in our patients show that changes in the inner retinal layers (including ganglion cell and inner plexiform layer) with disruption of normal macular architecture supports a diagnosis of retinal artery occlusion. Our results support the use of OCT imaging for patients with monocular visual loss of ...

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      Mentions: Laura J. Balcer
    1-3 of 3
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  2. Topics in the News

    1. (1 articles) UCSF
    2. (1 articles) University College London
    3. (1 articles) Axel Petzold
    4. (1 articles) Ari J. Green
    5. (1 articles) Timm Oberwahrenbrock
    6. (1 articles) Laura J. Balcer
    7. (1 articles) Friedemann Paul
    8. (1 articles) Sungkyunkwan University
    9. (1 articles) Dresden University of Technology
    10. (1 articles) Northwestern University
    11. (1 articles) Francesco Prati
    12. (1 articles) Joon Mo Kim
    13. (1 articles) Edmund Koch
    14. (1 articles) Brian E. Applegate
    15. (1 articles) Lars Kirsten
    16. (1 articles) Wihan Kim
    17. (1 articles) Javier A. Jo
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    Utility of optical coherence tomography in the evaluation of monocular visual loss related to retinal ischemia Monitoring the Course of MS With Optical Coherence Tomography Multicenter reliability of semiautomatic retinal layer segmentation using OCT Medical treatment of inflammatory punctual stenosis monitored by anterior segment optical coherence tomography Development and Validation of a Deep Learning System for Diagnosing Glaucoma Using Optical Coherence Tomography Methylene blue-filled biodegradable polymer particles as a contrast agent for optical coherence tomography Optical coherence tomography for thyroid pathology: 3D analysis of tissue microstructure Mathematical Analysis of Texture Indicators for the Segmentation of Optical Coherence Tomography Images Comparison of Current Optical Coherence Tomography Angiography Methods in Imaging Retinal Hemangioblastomas New findings useful for clinical practice using swept-source optical coherence tomography angiography in the follow-up of active ocular toxoplasmosis Stanford University Receives NIH Grant for Imaging Structure and Function Robotics and Virtual Reality for Optical Coherence Tomography-Guided Ophthalmic Surgery and Diagnostics (Thesis)