1. Articles from Sara Rey

    1-3 of 3
    1. Non-Invasive Detection of Early Retinal Neuronal Degeneration by Ultrahigh Resolution Optical Coherence Tomography

      Non-Invasive Detection of Early Retinal Neuronal Degeneration by Ultrahigh Resolution Optical Coherence Tomography

      Optical coherence tomography (OCT) has revolutionises the diagnosis of retinal disease based on the detection of microscopic rather than subcellular changes in retinal anatomy. However, currently the technique is limited to the detection of microscopic rather than subcellular changes in retinal anatomy. However, coherence based imaging is extremely sensitive to both changes in optical contrast and cellular events at the micrometer scale, and can generate subtle changes in the spectral content of the OCT image. Here we test the hypothesis that OCT image speckle (image texture) contains information regarding otherwise unresolvable features such as organelle changes arising in the early ...

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    2. Fast dispersion encoded full range optical coherence tomography for retinal imaging at 800 nm and 1060 nm

      Fast dispersion encoded full range optical coherence tomography for retinal imaging at 800 nm and 1060 nm

      The dispersion mismatch between sample and reference arm in frequency-domain optical coherence tomography (OCT) can be used to iteratively suppress complex conjugate artifacts and thereby increase the imaging range. In this paper, we propose a fast dispersion encoded full range (DEFR) algorithm that detects multiple signal components per iteration. The influence of different dispersion levels on the reconstruction quality is analyzed experimentally using a multilayered scattering phantom and in vivo retinal tomograms at 800 nm. Best results have been achieved with 30 mm SF11, with neglectable resolution decrease due to finite resolution of the spectrometer. Our fast DEFR algorithm achieves ...

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    3. Visualization of 3D cell migration using high speed ultrahigh resolution optical coherence tomography

      Visualization of 3D cell migration using high speed ultrahigh resolution optical coherence tomography

      Using high speed ultrahigh resolution optical coherence tomography (OCT) at 800nm, non-invasive 3D cellular imaging has been accomplished. Cellular resolution imaging on and within these types of substrates is not possible with conventional microscopy techniques such as interference contrast microscopy, and requires the use of fluorescent staining. It is possible to achieve data acquisition rates of 20,000 samples per second with OCT which, in combination with its high axial and transverse resolution (>2-3µm), allows it to be used as a non-invasive technique to analyze cell migration in 3D with time. Comparatively high penetration depth also makes OCT a ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) Cardiff University
    2. (3 articles) Wolfgang Drexler
    3. (3 articles) Bernd M. Hofer
    4. (3 articles) Sara M. Rey
    5. (3 articles) Boris Pova┼żay
    6. (2 articles) Boris Hermann
    7. (2 articles) Angelika Unterhuber
    8. (1 articles) Medical University of Vienna
    9. (1 articles) Ling Wang
    10. (1 articles) Adrian Harwood
    11. (1 articles) UCLA
    12. (1 articles) University of Wisconsin
    13. (1 articles) University of St. Andrews
    14. (1 articles) Duke University
    15. (1 articles) Kishan Dholakia
    16. (1 articles) Cynthia A. Toth
    17. (1 articles) Richard B. Rosen
    18. (1 articles) Optovue
    19. (1 articles) Leica
    20. (1 articles) Heidelberg Engineering
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    Visualization of 3D cell migration using high speed ultrahigh resolution optical coherence tomography Fast dispersion encoded full range optical coherence tomography for retinal imaging at 800 nm and 1060 nm Non-Invasive Detection of Early Retinal Neuronal Degeneration by Ultrahigh Resolution Optical Coherence Tomography Monitoring Response to Platelet-Rich Plasma in Patients with Alopecia Areata with Optical Coherence Tomography: A Case Series NONPERFUSION AREA QUANTIFICATION IN BRANCH RETINAL VEIN OCCLUSION: A WIDEFIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY STUDY Nonperfusion Assessment in Retinal Vein Occlusion: Comparison between Ultra-Widefield Fluorescein Angiography and Widefield OCT-Angiography Anatomical Location of the Raphe and Extended Raphe in the Human Retina: Implications for Assessment of the Optic Nerve with OCT Assessing the Influence of OCT-A Device and Scan Size on Retinal Vascular Metrics Repeatability and Reproducibility of Axial and Lateral Measurements on Handheld Optical Coherence Tomography Systems Compared with Tabletop System Bleb Morphology Using Anterior-Segment Optical Coherence Tomography after Ahmed Glaucoma Valve Surgery with Tenon Capsule Resection Utility of optical coherence tomography angiography in pregnancy-associated central serous chorioretinopathy Multimodal Imaging at Depth Using Innovations in Raman Spectroscopy and Optical Coherence Tomography