1. Articles from Atul Kumar

    1-26 of 26
    1. Intraoperative Optical Coherence Tomography Guided Ocular Surgeries: Critical Analysis of Clinical Role and Future Perspectives

      Intraoperative Optical Coherence Tomography Guided Ocular Surgeries: Critical Analysis of Clinical Role and Future Perspectives

      Intraoperative imaging of ocular tissues for diagnostic and therapeutic applications has gained immense admiration in recent years. The real time cross-sectional imaging, as well as three and four dimensional reconstruction abilities of intraoperative optical coherence tomography (iOCT), has enhanced our knowledge on many fronts in surgical maneuvers. In this review, we discuss the iOCT discovered constructive knowledge in the cornea, cataract, refractive, glaucoma, pediatric ocular, and various retinal conditions. The practical utility with decision modifying aspects along the specified ocular tissues and with respect to specific ocular entities have been narrated. Moreover, limitations and future directions have also been emphasized ...

      Read Full Article
    2. Peripapillary Retinal and Choroidal Perfusion in Nonarteritic Ischemic Optic Neuropathy Using Optical Coherence Tomography Angiography

      Peripapillary Retinal and Choroidal Perfusion in Nonarteritic Ischemic Optic Neuropathy Using Optical Coherence Tomography Angiography

      SIGNIFICANCE Nonarteritic ischemic optic neuropathy (NAION) has been linked with vascular insufficiency, although the pathophysiology remains elusive. Optical coherence tomography angiography (OCTA) is a promising technology that noninvasively evaluates optic disc perfusion and that may help to characterize peripapillary vascular changes in NAION. PURPOSE This study aimed to evaluate peripapillary vascularity in NAION eyes and to compare it with fellow unaffected eyes and healthy control eyes using OCTA. METHODS In this cross-sectional study, OCTA of the optic nerve head was obtained in 10 nonacute unilateral NAION and 12 healthy age-matched controls using ZEISS Angioplex. Quantitative analysis of peripapillary retinal and ...

      Read Full Article
    3. Three-years follow-up swept source optical coherence tomography angiography findings in post-fever retinitis

      Three-years follow-up swept source optical coherence tomography angiography findings in post-fever retinitis

      Post fever retinitis (PFR), characterized by multiple cotton wool spot like lesions in the posterior pole, is commonly reported following viral and bacterial infections. Retinal perfusion defects have been documented with the help of optical coherence tomography angiography (OCTA) in cases of PFR. But long term changes in such cases have not been reported earlier. In the following report, we have described the swept-source OCTA findings of two PFR patients at initial presentation and three years follow-up. Initial OCTA scans may not provide accurate information regarding the perfusion status due to associated retinal edema and inflammation. However, persisting perfusion defects ...

      Read Full Article
    4. In vivo optical biopsy of choroidal osteoma: a swept source optical coherence tomography–based tumor characterization

      In vivo optical biopsy of choroidal osteoma: a swept source optical coherence tomography–based tumor characterization

      Objective: To study tumor characteristics of choroidal osteoma by swept source optical coherence tomography. Methods: A retrospective case series done at tertiary referral center in northern India. All patients diagnosed with choroidal osteoma examined on swept source optical coherence tomography were included. Swept source optical coherence tomography images were analyzed for integrity of retinal layers—intraretinal layers, outer retinal layers (photoreceptor), retinal pigment epithelium, and contour abnormalities. Choroidal changes assessed were tumor attributes such as shape, depth of choroidal involvement, tumor mass reflectivity pattern, tumor vascularity, and evolutionary structural abnormalities such as deossification, focal depressions, or choroidal neovascular membrane. Results ...

      Read Full Article
    5. Intraoperative optical coherence tomography-guided subretinal cocktail injection in a case of ruptured retinal artery macro-aneurysm with multilevel bleed

      Intraoperative optical coherence tomography-guided subretinal cocktail injection in a case of ruptured retinal artery macro-aneurysm with multilevel bleed

      Submacular hemorrhage (SMH) following ruptured retinal artery macro aneurysm (RRAM) has better prognosis as compared to other etiologies. Timely intervention from as early as 24 h to less than 7 days is known to provide better visual outcomes in such cases. A variety of surgical techniques have been described in the treatment of RRAM. In this case report, we describe the advantages of intraoperative optical coherence tomography-guided sub-retinal injection of a cocktail mixture consisting of recombinant tissue plasminogen activator, bevacizumab, and air. Faster visual recovery with an immediate displacement of sub-macular bleed can be achieved with this technique in cases ...

      Read Full Article
    6. Unique observations on swept source optical coherence tomography in a case of morning glory optic disc anomaly with associated retinal detachment

      Unique observations on swept source optical coherence tomography in a case of morning glory optic disc anomaly with associated retinal detachment

      A 7-year-old female presented with a diminution of vision in her right eye (RE) since birth, which was deteriorating further for the last few months. Her best-corrected visual-acuity (BCVA) was 20/400 in the RE and 20/20 in the left eye (LE). RE fundus showed funnel-shaped excavated optic disc (OD) suggestive of morning glory disc anomaly (MGDA) with an adjacent retinal detachment (RD), involving the macula. [Figure 1] a A retinal break could not be identified clinically. Radial swept source optical coherence tomography (SS-OCT) (DRI-Topcon) scans revealed preretinal floating vitreous opacities, central fibrotic glial membrane (FGM) over the OD ...

      Read Full Article
    7. Age-related changes in macular vessels and their perfusion densities on optical coherence tomography angiography

      Age-related changes in macular vessels and their perfusion densities on optical coherence tomography angiography

      Purpose: To evaluate age-related changes in macular vessels and their perfusion densities using optical coherence tomography angiography (OCTA). Methods: A total of 108 eyes of 54 healthy subjects between the age group of 11 to 60 years having unaided visual acuity of 20/20 were studied on spectral domain OCTS using 3 * 3 mm macula protocol. These subjects were divided into 5 groups; Group 1: 11–20 years, Group 2: 21–30 years, Group 3: 31–40 years, Group 4: 41–50 years, and Group 5: 51–60 years. An early treatment diabetic retinopathy study (ETDRS) grid overlay at the ...

      Read Full Article
    8. Role of microscope-integrated optical coherence tomography in detecting myopic choroidal neovascularization intraoperatively in a case of myopic rhegmatogenous retinal detachment

      Role of microscope-integrated optical coherence tomography in detecting myopic choroidal neovascularization intraoperatively in a case of myopic rhegmatogenous retinal detachment

      A 22-year-old boy presented to our center with subtotal rhegmatogenous retinal detachment (RRD). His best-corrected visual acuity (BCVA) was 20/1200 in the affected eye. Posterior segment examination revealed large superotemporal horse-shoe tear with multiple lattices [Figure 1] a and [Figure 1] b. The patient underwent vitreoretinal surgery with an encircling band and silicone oil tamponade using 3D heads-up visualization system. [Figure 1] c and [Figure 1] d Intraoperatively, brilliant blue G dye and PFCL (perflurocarbon liquid) were injected to peel the internal limiting membrane. However, microscope-integrated optical coherence tomography (mi-OCT) revealed subretinal fluid persistent at the posterior pole along ...

      Read Full Article
    9. Swept-source optical coherence tomography features of regressed macular retinoblastoma

      Swept-source optical coherence tomography features of regressed macular retinoblastoma

      Purpose: To describe the swept-source optical coherence tomography (SS-OCT) features of regressed macular retinoblastoma (RB). Methods: A cross-sectional observational study was carried out in 13 patients with regressed macular RB with good fixation in at least one eye. Fundus photography and SS-OCT were documented. High-resolution scans with good signal strength were selected. The types of clinical regression and SS-OCT characteristics of the regressed lesions (presence of vitreous detachment, intratumor schisis/cavitation, calcification, foveal dip, and OCT pattern) were noted. Results: Of the 13 eyes, 7 (53%) were group B, 4 (30%) were group C, and 2 (17%) were group D ...

      Read Full Article
    10. Swept Source Optical Coherence Tomography Analysis of the Margin of Choroidal Coloboma : New Insights

      Swept Source Optical Coherence Tomography Analysis of the Margin of Choroidal Coloboma : New Insights

      Purpose To study the retinal architecture and vitreo-retinal interface at the edge of choroidal colobomata using swept source optical coherence tomography (SS-OCT). Design: Prospective observational case series at a tertiary eye care center. Participants Patients of choroidal coloboma presenting to ophthalmology department and fulfilling the inclusion criteria of the study. Testing SS-OCT was done in 30 eyes of 20 patients of choroidal coloboma. Main Outcome Measures The primary objective was to describe the OCT features at the margin of coloboma. Results SS-OCT of the coloboma margin revealed new features in addition to the previously described findings. Two types of transition ...

      Read Full Article
    11. Assessment of macular vascular plexus density using optical coherence tomography angiography in cases of strabismic amblyopia

      Assessment of macular vascular plexus density using optical coherence tomography angiography in cases of strabismic amblyopia

      Purpose: To evaluate the superficial retinal vascular plexus density using optical coherence tomography angiography (OCTA) in cases of strabismic amblyopia. Methods: Ten eyes of 10 patients with purely strabismic amblyopia underwent detailed ocular evaluation followed by the assessment of the superficial retinal plexus vascular density using OCTA (Topcon DRI OCT Triton, Swept Source OCT, Topcon, Japan). Ten contralateral normal eyes of the same patients were considered as control. All these 20 eyes underwent a 4.5 × 4.5 mm cube scan OCTA centered at the fovea. Using the Topcon propriety software all 20 eyes were assessed for the capillary plexus ...

      Read Full Article
    12. Choroidal thickness in normal Indian eyes using swept-source optical coherence tomography

      Choroidal thickness in normal Indian eyes using swept-source optical coherence tomography

      Purpose: The purpose of this study is to provide normative database for subfoveal choroidal thickness in Indian eyes using swept-source optical coherence tomography. Methods: This is a cross-sectional study based at a tertiary eye care center in Northern India. Two hundred and thirty eight eyes of 119 healthy subjects were examined in terms of axial length, spherical equivalent, and choroidal thickness. Inclusion criteria included age 19–60 years, no retinal or choroidal disorder, and patients with clear media and good fixation. Patients with high hypermetropia (>4 D) or myopia (>6 D) or any systemic disease likely to affect choroidal thickness ...

      Read Full Article
    13. Commentary: Influence of orientation of the external linear incision created by the 25-gauge trocar and related factors on sclerotomy closure: A clinical and optical coherence tomographic study

      Commentary: Influence of orientation of the external linear incision created by the 25-gauge trocar and related factors on sclerotomy closure: A clinical and optical coherence tomographic study

      The panorama of vitreoretinal surgery has considerably transformed with the advent of microincision vitrectomy surgery (MIVS). [1] Although the central idea of MIVS was to create a microincision sclerotomy, it never accomplished the goal of being sutureless. In our clinical experience, we advocate the concept of suturing the port site, if needed, to avoid postoperative wound leak and hypotony. [2] The art of wound construction is the talk of the town in the current scenario of vitreoretinal surgery to avoid untoward complication and even in terms of cosmesis. The IJO article “Influence of orientation of the external linear incision created ...

      Read Full Article
    14. Fleck-like deposits and swept source optical coherence tomography characteristics in a case of confirmed ocular chalcosis

      Fleck-like deposits and swept source optical coherence tomography characteristics in a case of confirmed ocular chalcosis

      A 36-year-old male presented with history of injury in the left eye 3 years back with a copper wire. Examination revealed the presence of typical sunflower cataract with golden yellow deposits over the anterior lens capsule with dull glow and old vitreous hemorrhage. Non-contrast computerized tomography revealed retained intraocular foreign body in the pars plana region. The patient underwent phacoemulsification with intraocular lens implantation followed by pars plana vitrectomy and foreign body removal. Intraoperatively, fleck-like deposits were noted on the retinal surface in a circinate manner around the fovea and also over mid-peripheral retina. Postoperative swept source optical coherence tomography ...

      Read Full Article
    15. Microscope-integrated optical coherence tomography-aided intraoperative diagnosis and management of peripheral tractional retinoschisis

      Microscope-integrated optical coherence tomography-aided intraoperative diagnosis and management of peripheral tractional retinoschisis

      A 48-year-old male, diagnosed case of Eales' vasculitis, presented with best-corrected visual acuity (BCVA) of hand movements with a near-total combined retinal detachment in the right eye (OD) and BCVA 6/9 in the left eye (OS). OD fundus showed fibrovascular proliferation (FVP) nasally at the equator and a retinal break located inferior to the FVP [Figure 1] a and [Figure 1] b. Swept-source optical coherence tomography (OCT) (Topcon Corp, Tokyo, Japan) showed a grade 1 epiretinal membrane (ERM) in both eyes (OU). Preoperative fluorescein angiography OCT was performed. The patient underwent 23-gauge pars plana vitrectomy (PPV) with ERM peeling ...

      Read Full Article
    16. Characterization of Idiopathic Choroidal Neovascularization Using Fluorescein Angiography, Indocyanine Green Angiography, and Optical Coherence Tomography Angiography

      Characterization of Idiopathic Choroidal Neovascularization Using Fluorescein Angiography, Indocyanine Green Angiography, and Optical Coherence Tomography Angiography

      BACKGROUND AND OBJECTIVE: To assess the usefulness of optical coherence tomography angiography (OCTA) in cases of idiopathic choroidal neovascularization (iCNV). PATIENTS AND METHODS: Seven eyes with suspected iCNV were evaluated using OCT, OCTA, fluorescein angiography (FA), and indocyanine green angiography (ICGA) and were followed up between 3 weeks and 4 weeks following an intravitreal anti-vascular endothelial growth factor (VEGF) injection. The utility of OCTA in the diagnosis and characterization of morphology of iCNV at baseline and follow-up was assessed. RESULTS: Morphology of vasculature comprising iCNV could be detected in all cases (100%) on OCTA and in 57% cases on ICGA ...

      Read Full Article
    17. TiO2 nanoparticles as exogenous contrast agent for 1 µm swept source optical coherence tomography: an in vitro study

      TiO2 nanoparticles as exogenous contrast agent for 1 µm swept source optical coherence tomography: an in vitro study

      Optical coherence tomography (OCT) is a rapidly evolving, robust technology that has profoundly changed the practice of medical imaging. Swept source OCT (SSOCT) combines the standard time domain and the spatially encoded frequency domain OCT. We have employed a high-speed SSOCT system that utilizes a swept source laser with an A-scan rate of 100 kHz and a central wavelength of 1060 nm for the imaging of the tissue. SSOCT at 1060 nm allows for high penetration in the tissue. TiO 2 nanoparticles (NPs) are mostly used for various experimental purposes as an exogenous imaging contrast agent. The in vitro imaging ...

      Read Full Article
      Mentions: Raju Poddar
    18. Optic disc coloboma with pit treated as glaucoma: diagnostic utility of ultrasound and swept source optical coherence tomography

      Optic disc coloboma with pit treated as glaucoma: diagnostic utility of ultrasound and swept source optical coherence tomography

      A 6-year-old boy presented as a known case of developmental glaucoma and was using topical travoprost in the right eye (RE) since 1 year. Highest recorded intraocular pressure (IOP) was 24 mm Hg in RE, whereas central corneal thickness was 540 µm. Visual acuity was 6/6 in both eyes. On examination, the anterior segment of both eyes was unremarkable. IOP was 16 mm Hg in RE and 20 mm Hg in the left eye. Fundus examination of RE revealed a large and pale optic disc, with a nearly absent inferior neuroretinal rim. The origin of the inferior vascular bundle ...

      Read Full Article
    19. Utility of microscope-integrated optical coherence tomography (MIOCT) in the treatment of myopic macular hole retinal detachment

      Utility of microscope-integrated optical coherence tomography (MIOCT) in the treatment of myopic macular hole retinal detachment

      Macular hole-associated retinal detachment in high myopia is described as a final stage in progression of myopic traction maculopathy (MTM). 1–3 Shimada et al 4 described the progressive stages of MTM from macular retinoschisis to serous retinal detachment in high myopia. Stage 4 MTM is characterised as disappearance of retinoschisis with progression to retinal detachment due to macular hole formation. It is hypothesised that vitreoschisis and abnormal vitreo-retinal interface create the premacular tangential traction. 5 6 Intraoperative triamcinolone acetonide is used to visualise the residual posterior vitreous cortex (PVC). We hereby describe the utility of microscope-integrated optical coherence tomography ...

      Read Full Article
    20. Combined Hamartoma of the Retina and Retinal Pigment Epithelium: An Optical Coherence Tomography-Based Reappraisal

      Combined Hamartoma of the Retina and Retinal Pigment Epithelium: An Optical Coherence Tomography-Based Reappraisal

      Purpose To analyze the optical coherence tomography (OCT) characteristics of combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) involving the macula. Design Retrospective, observational case series. Methods Setting: Single institutional. Study population: Fourteen consecutive patients of CHRRPE were included. Observation procedures: The authors analyzed the clinical features, color fundus photography, and swept source or spectral domain OCT of all the involved eyes. Main outcome measures: OCT characteristics, especially the involvement of the retinal pigment epithelium (RPE). Results Total 16 eyes of 5 female and 9 male patients were analyzed. The mean age (±SD) was 17.9 ± 6.4 ...

      Read Full Article
    21. Intravitreal cysticercosis with full thickness macular hole: management outcome and intraoperative optical coherence tomography features

      Intravitreal cysticercosis with full thickness macular hole: management outcome and intraoperative optical coherence tomography features

      Ocular cysticercosis is a serious condition with a potential for complete vision loss if left untreated. Intravitreal cysticercosis is the most common ocular form of cysticercosis and is associated with retinal detachment, retinal traction, subretinal scarring and vitritis. To the best of our knowledge, there is no report of the occurrence of a live intravitreal cysticercosis with a full thickness macular hole (FTMH) in the literature. We here report a case of live intravitreal cysticercosis with a FTMH along with its management and intraoperative optical coherence tomography features of the live cysticercus.

      Read Full Article
    22. Swept-source optical coherence tomography findings in peripheral drusen

      Swept-source optical coherence tomography findings in peripheral drusen

      A 50-year-old otherwise healthy female was examined during her routine checkup. The unaided visual acuity was 20/20 OU. Anterior segment examination of OU including intraocular pressure was unremarkable. Funduscopic examination of OU (Optos Inc.) revealed small multiple, discrete, yellow spots in the peripheral fundus more so in the nasal area [Figure 1] a and [Figure 1] b. On ultra wide field autofluorescence imaging, these lesions appeared mostly as hyperautofluorescent with few being hypoautofluorescent [Figure 1] c and [Figure 1] d. The patient was diagnosed to have peripheral drusen. The posteriorly located drusen [Figure 2] a, seen as blue circle ...

      Read Full Article
    23. Intraoperative optical coherence tomography guided removal of premacular hemorrhage in Valsalva retinopathy

      Intraoperative optical coherence tomography guided removal of premacular hemorrhage in Valsalva retinopathy

      A 32-year-old male presented with 4 weeks history of sudden decrease of vision in his right eye following a bout of cough. The left eye was normal. The anterior segment in the right eye was normal. A dilated fundus of the right eye showed a 6 mm × 4 mm area of premacular hemorrhage [Figure 1] a. Spectral domain optical coherence tomography (SD-OCT) showed smooth convex dome-shaped hyper-reflectivity from blood with shadowing underneath [Figure 1] b. After informed consent, the patient underwent 25-gauge pars plana vitrectomy with removal of premacular blood. The premacular blood remained unchanged after triamcinolone-assisted posterior vitreous detachment ...

      Read Full Article
    24. Swept source: optical coherence tomography angiography features of choroidal osteoma with choroidal neovascular membrane

      Swept source: optical coherence tomography angiography features of choroidal osteoma with choroidal neovascular membrane

      A 16-year-old boy presented with best-corrected visual acuity of 6/18 OD. OS was within normal limits, as was anterior segment OD. A focal whitish-yellow plaque lesion with overlying areas of depigmentation, and retinal atrophy in the central and superior lateral macula were noted in OD. A choroidal neovascular membrane (CNVM) with subretinal haemorrhage was seen at the lesion's inferior medial edge, involving the fovea (figure 1A). Therefore, diagnosis of choroidal osteoma 1 (CO) was made and confirmed on sonography, with a highly acoustic elevated lesion causing a corresponding shadow (figure 1B).

      Read Full Article
    25. Intraoperative Optical Coherence Tomography (OCT): A New Frontier in Vitreo-Retinal Surgery

      Intraoperative Optical Coherence Tomography (OCT): A New Frontier in Vitreo-Retinal Surgery

      Optical coherence tomography, a non-invasive imaging technique is an indispensable tool in the armamentarium of modern day ophthalmologists. With evolution in technology, modern day OCT machines (swept source OCT) are able to provide high resolution images of vitreous, retina, choroid and sclera simultaneously. As a better understanding of various retinal disorders was obtained with the use of OCT, the need for refinement of vitreo-retinal surgery utilizing intra-operative OCT was felt. While earlier versions of intra-operative OCT were hand held, the newer versions are fully integrated with microscope (MIOCT). MIOCT provides spectral-domain OCT (SD-OCT) images while performing the surgery on heads ...

      Read Full Article
    1-26 of 26
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (3 articles) L V Prasad Eye Institute
    2. (1 articles) Indian Institute of Technology at Delhi
    3. (1 articles) Raju Poddar
    4. (1 articles) Miguel A. Materin
    5. (1 articles) Topcon Medical Systems
    6. (1 articles) UCLA
    7. (1 articles) University of Groningen
    8. (1 articles) University of Wisconsin
    9. (1 articles) University of St. Andrews
    10. (1 articles) Duke University
    11. (1 articles) Kishan Dholakia
    12. (1 articles) Cynthia A. Toth
    13. (1 articles) Optovue
    14. (1 articles) Leica
    15. (1 articles) Heidelberg Engineering
  3. Popular Articles

  4. Picture Gallery

    Intraoperative Optical Coherence Tomography (OCT): A New Frontier in Vitreo-Retinal Surgery Swept source: optical coherence tomography angiography features of choroidal osteoma with choroidal neovascular membrane Intraoperative optical coherence tomography guided removal of premacular hemorrhage in Valsalva retinopathy Swept-source optical coherence tomography findings in peripheral drusen Intravitreal cysticercosis with full thickness macular hole: management outcome and intraoperative optical coherence tomography features Combined Hamartoma of the Retina and Retinal Pigment Epithelium: An Optical Coherence Tomography-Based Reappraisal Utility of microscope-integrated optical coherence tomography (MIOCT) in the treatment of myopic macular hole retinal detachment Optic disc coloboma with pit treated as glaucoma: diagnostic utility of ultrasound and swept source optical coherence tomography TiO2 nanoparticles as exogenous contrast agent for 1 µm swept source optical coherence tomography: an in vitro study Fleck-like deposits and swept source optical coherence tomography characteristics in a case of confirmed ocular chalcosis Long-Term Arterial Remodeling After Bioresorbable Scaffold Implantation 4-Year Follow-up of Quantitative Coronary Angiography, Histology and Optical Coherence Tomography Visualization of Bacterial Colonization and Cellular Layers in a Gut-on-a-Chip System Using Optical Coherence Tomography