1. Articles from Richard W. Cheng

    1-2 of 2
    1. Validation of Optical Coherence Tomography Retinal Segmentation in Neurodegenerative Disease

      Validation of Optical Coherence Tomography Retinal Segmentation in Neurodegenerative Disease

      Purpose : This study assessed agreement between an automated spectral-domain optical coherence tomography (SD-OCT) retinal segmentation software and manually corrected segmentation to validate its use in a prospective clinical study of neurodegenerative diseases (NDD). Methods : The sample comprised 30 subjects with NDD, including vascular cognitive impairment, frontotemporal dementia, Parkinson's disease, and Alzheimer's disease. Macular SD-OCT scans were acquired and segmented using Heidelberg Spectralis. For the central foveal B scan of each eye, eight segmentation lines were examined to determine the proportion of each line that the software erroneously delineated. Errors in four lines were manually corrected in all B ...

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    2. Relationship between Retinal Blood Flow and Arterial Oxygen

      Relationship between Retinal Blood Flow and Arterial Oxygen

      Retinal blood flow (RBF) increases in response to a reduction in oxygen (hypoxia), but decreases in response to increased oxygen (hyperoxia). However, the relationship between blood flow and the arterial partial pressure of oxygen has not been quantified and modeled in the retina in particular the vascular reserve and resting tonus of the vessels. The objective of this study was to determine the limitations of the retinal vasculature by modeling the relationship between RBF and oxygen. Retinal vascular responses were measured in 13 subjects for 8 different blood gas conditions, with the end-tidal partial pressure of oxygen (P ET O ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) University of Toronto
    2. (1 articles) University of Waterloo
    3. (1 articles) Optovue
    4. (1 articles) University of Sydney
    5. (1 articles) University of Zurich
    6. (1 articles) UCSD
    7. (1 articles) University of Pittsburgh
    8. (1 articles) L V Prasad Eye Institute
    9. (1 articles) Giuseppe Querques
    10. (1 articles) Carl Zeiss Meditec
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    Relationship between Retinal Blood Flow and Arterial Oxygen Validation of Optical Coherence Tomography Retinal Segmentation in Neurodegenerative Disease Optical coherence tomography features of neovascularization in proliferative diabetic retinopathy: a systematic review Retinal microvascular metrics in untreated essential hypertensives using optical coherence tomography angiography Optical coherence tomography angiography findings of fellow eye of proliferative macular telangiectasia type 2: Long term study Reorganization of the perifoveal microvasculature after macular hole closure assessed via optical coherence tomography angiography Optical coherence tomography angiography (OCTA) findings in Serpiginous Choroiditis Changes in retinal layer thickness with maturation in the dog: an in vivo spectral domain - optical coherence tomography imaging study Optical coherence tomography angiography analysis of fabry disease An unsupervised hierarchical approach for automatic intra‐retinal cyst segmentation in spectral‐domain optical coherence tomography images Towards quantitative assessment of burn based on photoacoustic and optical coherence tomography Cellular Scale Imaging of Transparent Retinal Structures and Processes Using Adaptive Optics Optical Coherence Tomography