1. Articles from Rohan Chawla

    1-26 of 26
    1. Peripapillary Retinal and Choroidal Perfusion in Nonarteritic Ischemic Optic Neuropathy Using Optical Coherence Tomography Angiography

      Peripapillary Retinal and Choroidal Perfusion in Nonarteritic Ischemic Optic Neuropathy Using Optical Coherence Tomography Angiography

      SIGNIFICANCE Nonarteritic ischemic optic neuropathy (NAION) has been linked with vascular insufficiency, although the pathophysiology remains elusive. Optical coherence tomography angiography (OCTA) is a promising technology that noninvasively evaluates optic disc perfusion and that may help to characterize peripapillary vascular changes in NAION. PURPOSE This study aimed to evaluate peripapillary vascularity in NAION eyes and to compare it with fellow unaffected eyes and healthy control eyes using OCTA. METHODS In this cross-sectional study, OCTA of the optic nerve head was obtained in 10 nonacute unilateral NAION and 12 healthy age-matched controls using ZEISS Angioplex. Quantitative analysis of peripapillary retinal and ...

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    2. In vivo optical biopsy of choroidal osteoma: a swept source optical coherence tomography–based tumor characterization

      In vivo optical biopsy of choroidal osteoma: a swept source optical coherence tomography–based tumor characterization

      Objective: To study tumor characteristics of choroidal osteoma by swept source optical coherence tomography. Methods: A retrospective case series done at tertiary referral center in northern India. All patients diagnosed with choroidal osteoma examined on swept source optical coherence tomography were included. Swept source optical coherence tomography images were analyzed for integrity of retinal layers—intraretinal layers, outer retinal layers (photoreceptor), retinal pigment epithelium, and contour abnormalities. Choroidal changes assessed were tumor attributes such as shape, depth of choroidal involvement, tumor mass reflectivity pattern, tumor vascularity, and evolutionary structural abnormalities such as deossification, focal depressions, or choroidal neovascular membrane. Results ...

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    3. Intraoperative optical coherence tomography-guided subretinal cocktail injection in a case of ruptured retinal artery macro-aneurysm with multilevel bleed

      Intraoperative optical coherence tomography-guided subretinal cocktail injection in a case of ruptured retinal artery macro-aneurysm with multilevel bleed

      Submacular hemorrhage (SMH) following ruptured retinal artery macro aneurysm (RRAM) has better prognosis as compared to other etiologies. Timely intervention from as early as 24 h to less than 7 days is known to provide better visual outcomes in such cases. A variety of surgical techniques have been described in the treatment of RRAM. In this case report, we describe the advantages of intraoperative optical coherence tomography-guided sub-retinal injection of a cocktail mixture consisting of recombinant tissue plasminogen activator, bevacizumab, and air. Faster visual recovery with an immediate displacement of sub-macular bleed can be achieved with this technique in cases ...

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    4. Unique observations on swept source optical coherence tomography in a case of morning glory optic disc anomaly with associated retinal detachment

      Unique observations on swept source optical coherence tomography in a case of morning glory optic disc anomaly with associated retinal detachment

      A 7-year-old female presented with a diminution of vision in her right eye (RE) since birth, which was deteriorating further for the last few months. Her best-corrected visual-acuity (BCVA) was 20/400 in the RE and 20/20 in the left eye (LE). RE fundus showed funnel-shaped excavated optic disc (OD) suggestive of morning glory disc anomaly (MGDA) with an adjacent retinal detachment (RD), involving the macula. [Figure 1] a A retinal break could not be identified clinically. Radial swept source optical coherence tomography (SS-OCT) (DRI-Topcon) scans revealed preretinal floating vitreous opacities, central fibrotic glial membrane (FGM) over the OD ...

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    5. Age-related changes in macular vessels and their perfusion densities on optical coherence tomography angiography

      Age-related changes in macular vessels and their perfusion densities on optical coherence tomography angiography

      Purpose: To evaluate age-related changes in macular vessels and their perfusion densities using optical coherence tomography angiography (OCTA). Methods: A total of 108 eyes of 54 healthy subjects between the age group of 11 to 60 years having unaided visual acuity of 20/20 were studied on spectral domain OCTS using 3 * 3 mm macula protocol. These subjects were divided into 5 groups; Group 1: 11–20 years, Group 2: 21–30 years, Group 3: 31–40 years, Group 4: 41–50 years, and Group 5: 51–60 years. An early treatment diabetic retinopathy study (ETDRS) grid overlay at the ...

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    6. Swept-source optical coherence tomography features of regressed macular retinoblastoma

      Swept-source optical coherence tomography features of regressed macular retinoblastoma

      Purpose: To describe the swept-source optical coherence tomography (SS-OCT) features of regressed macular retinoblastoma (RB). Methods: A cross-sectional observational study was carried out in 13 patients with regressed macular RB with good fixation in at least one eye. Fundus photography and SS-OCT were documented. High-resolution scans with good signal strength were selected. The types of clinical regression and SS-OCT characteristics of the regressed lesions (presence of vitreous detachment, intratumor schisis/cavitation, calcification, foveal dip, and OCT pattern) were noted. Results: Of the 13 eyes, 7 (53%) were group B, 4 (30%) were group C, and 2 (17%) were group D ...

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    7. Assessment of macular vascular plexus density using optical coherence tomography angiography in cases of strabismic amblyopia

      Assessment of macular vascular plexus density using optical coherence tomography angiography in cases of strabismic amblyopia

      Purpose: To evaluate the superficial retinal vascular plexus density using optical coherence tomography angiography (OCTA) in cases of strabismic amblyopia. Methods: Ten eyes of 10 patients with purely strabismic amblyopia underwent detailed ocular evaluation followed by the assessment of the superficial retinal plexus vascular density using OCTA (Topcon DRI OCT Triton, Swept Source OCT, Topcon, Japan). Ten contralateral normal eyes of the same patients were considered as control. All these 20 eyes underwent a 4.5 × 4.5 mm cube scan OCTA centered at the fovea. Using the Topcon propriety software all 20 eyes were assessed for the capillary plexus ...

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    8. Advanced Optical Coherence Tomography Angiography Analysis of Age-related Macular Degeneration Complicated by Onset of Unilateral Choroidal Neovascularization

      Advanced Optical Coherence Tomography Angiography Analysis of Age-related Macular Degeneration Complicated by Onset of Unilateral Choroidal Neovascularization

      I read the article by Arrigo and associates 1 on optical coherence tomography angiography (OCTA) analysis of retinal vasculature in cases of unilateral choroidal neovascularization (CNV) using quantitative analytical techniques with great interest. However, I have few concerns.

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    9. Intraoperative optical coherence tomography-guided scleral suture passage while performing surgery on extraocular muscles

      Intraoperative optical coherence tomography-guided scleral suture passage while performing surgery on extraocular muscles

      Sir, Microscope-integrated intraoperative optical coherence tomography (iOCT, 2 mm depth penetration) helps in achieving the optimal results by providing the real-time images of tissue manipulation during the surgery. The iOCT is of great value while performing lamellar corneal surgeries, cataract surgeries, and intraocular lens implantation surgery. [1] , [2] It has also been noted to provide an advantage during placement of the glaucoma drainage devices in cadaveric eyes and needling of the blebs. [3] , [4] Pasricha et al . described the four-dimensional visualizations of the muscle and the scleral wound while passing the scleral sutures. [5] A 45-year-old male patient with alternate ...

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    10. Letter to the Editor: Optical Coherence Tomography Angiography of Choroidal Hemangioma

      Letter to the Editor: Optical Coherence Tomography Angiography of Choroidal Hemangioma

      Dear Editor, We read with interest the article on optical coherence tomography angiography (OCTA) of a suspected case of choroidal hemangioma. 1 We want to humbly discuss a few facts. The authors mention that “To date, findings from optical coherence tomography angiography (OCTA) have yet to be reported for a choroidal hemangioma.” However, in 2017 we had published our findings in cases of choroidal hemangioma before and after treatment with laser. 2 In an asymptomatic patient with an incidentally detected choroidal mass multiple differential diagnoses are possible, including metastasis. It would be interesting to know how the authors excluded other ...

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    11. Microscope-integrated optical coherence tomography-aided intraoperative diagnosis and management of peripheral tractional retinoschisis

      Microscope-integrated optical coherence tomography-aided intraoperative diagnosis and management of peripheral tractional retinoschisis

      A 48-year-old male, diagnosed case of Eales' vasculitis, presented with best-corrected visual acuity (BCVA) of hand movements with a near-total combined retinal detachment in the right eye (OD) and BCVA 6/9 in the left eye (OS). OD fundus showed fibrovascular proliferation (FVP) nasally at the equator and a retinal break located inferior to the FVP [Figure 1] a and [Figure 1] b. Swept-source optical coherence tomography (OCT) (Topcon Corp, Tokyo, Japan) showed a grade 1 epiretinal membrane (ERM) in both eyes (OU). Preoperative fluorescein angiography OCT was performed. The patient underwent 23-gauge pars plana vitrectomy (PPV) with ERM peeling ...

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    12. Characterization of Idiopathic Choroidal Neovascularization Using Fluorescein Angiography, Indocyanine Green Angiography, and Optical Coherence Tomography Angiography

      Characterization of Idiopathic Choroidal Neovascularization Using Fluorescein Angiography, Indocyanine Green Angiography, and Optical Coherence Tomography Angiography

      BACKGROUND AND OBJECTIVE: To assess the usefulness of optical coherence tomography angiography (OCTA) in cases of idiopathic choroidal neovascularization (iCNV). PATIENTS AND METHODS: Seven eyes with suspected iCNV were evaluated using OCT, OCTA, fluorescein angiography (FA), and indocyanine green angiography (ICGA) and were followed up between 3 weeks and 4 weeks following an intravitreal anti-vascular endothelial growth factor (VEGF) injection. The utility of OCTA in the diagnosis and characterization of morphology of iCNV at baseline and follow-up was assessed. RESULTS: Morphology of vasculature comprising iCNV could be detected in all cases (100%) on OCTA and in 57% cases on ICGA ...

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    13. Ocular toxicity due to colours used during Holi celebration in India: Correlation of clinical findings with the anterior segment OCT

      Ocular toxicity due to colours used during Holi celebration in India: Correlation of clinical findings with the anterior segment OCT

      Purpose: To correlate the anatomical extent of ocular surface toxicity due to colours using anterior segment optical coherence tomography with the clinical findings. Methods: Patients presenting to our emergency department with ocular colour toxicity during the Holi festival celebrations from 2 nd March 2018 to 5 th March 2018 were assessed for any adnexal, conjunctival, corneal and anterior chamber findings, as well as findings on anterior segment optical coherence tomography (ASOCT). Results: A total of 21 patients were observed. The average age was 23 years with 16 patients being male (76.19%). Bilateral ocular involvement was more common (in 13 ...

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    14. Swept source optical coherence tomography-angiography of an infarct of a small intra-neural branch of central retinal artery simulating cilio-retinal artery

      Swept source optical coherence tomography-angiography of an infarct of a small intra-neural branch of central retinal artery simulating cilio-retinal artery

      A 56-year-old man with episodic transient visual loss in right eye (OD), of 2 days duration. He was not symptomatic at presentation and was using anti-coagulants for cardiovascular disease. Visual acuity was 6/6 both eyes (OU). Intra-ocular pressure and anterior segment were normal OU. OD had a finger like area of macular whitening sparing the fovea. This area corresponded to the vascular bed of a clinically appearing cilio-retinal artery (cilio-RA) [Figure 1] a. However, on fluorescein angiography, the artery filled along with branches of central RA (CRA) [Figure 1] b and [Figure 1] c. Swept source optical coherence tomography ...

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    15. Retinal Arteriovenous Malformation Assessment Using Swept-Source OCT Angiography

      Retinal Arteriovenous Malformation Assessment Using Swept-Source OCT Angiography

      Swept-source optical coherence tomography angiography (SS-OCTA) is a promising new imaging modality for assessing retinal and choroidal vasculature. Faster scanning speed, large number of A-scan acquisition, and enhanced depth penetration has enhanced the detailed analysis of retinal layers. The authors discuss SS-OCTA features of a rare case of retinal arteriovenous malformation. Image analysis revealed the anomalous large-caliber vessels occupying up to the entire retinal thickness with associated echolucent changes in the inner retinal layers surrounding the retinal vessels, along with disruption of the outer retinal layers, including the inner/outer segments of photoreceptors beneath the large tortuous vessels outside the ...

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    16. Swept source optical coherence tomography-angiography of choroid in choroidal hemangioma before and after laser photocoagulation

      Swept source optical coherence tomography-angiography of choroid in choroidal hemangioma before and after laser photocoagulation

      Swept source optical coherence tomography-angiography (OCT-angiography) gives us a unique opportunity to study the vasculature of choroidal lesions in vivo . We describe the OCT angiographic characteristics of circumscribed choroidal hemangioma before and after laser photocoagulation. Medium-sized choroidal vessels/vessels on the tumor surface become predominantly visible after laser photocoagulation due to laser-induced damage to the overlying choriocapillaris. OCT-angiography adds a new dimension to in vivo analysis of vascular changes in choroid due to choroidal tumors and their response to therapy.

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    17. Combined Hamartoma of the Retina and Retinal Pigment Epithelium: An Optical Coherence Tomography-Based Reappraisal

      Combined Hamartoma of the Retina and Retinal Pigment Epithelium: An Optical Coherence Tomography-Based Reappraisal

      Purpose To analyze the optical coherence tomography (OCT) characteristics of combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) involving the macula. Design Retrospective, observational case series. Methods Setting: Single institutional. Study population: Fourteen consecutive patients of CHRRPE were included. Observation procedures: The authors analyzed the clinical features, color fundus photography, and swept source or spectral domain OCT of all the involved eyes. Main outcome measures: OCT characteristics, especially the involvement of the retinal pigment epithelium (RPE). Results Total 16 eyes of 5 female and 9 male patients were analyzed. The mean age (±SD) was 17.9 ± 6.4 ...

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    18. Omega Sign: A Distinct Optical Coherence Tomography Finding in Macular Combined Hamartoma of Retina and Retinal Pigment Epithelium

      Omega Sign: A Distinct Optical Coherence Tomography Finding in Macular Combined Hamartoma of Retina and Retinal Pigment Epithelium

      BACKGROUND AND OBJECTIVE: To report a distinct optical coherence tomography (OCT) appearance of macular combined hamartoma of retina and retinal pigment epithelium (CHRRPE). \ PATIENTS AND METHODS: This is a retrospective case series of four eyes of four patients with macular CHRRPE who were assessed with the help of color fundus photographs, swept-source OCT (SS-OCT), and fundus fluorescein angiography wherever required. RESULTS: All four patients presented with decreased visual acuity. SS-OCT in all patients showed adherent epiretinal membrane (ERM) and localized thickening of underlying retina. An omega-shaped disorganization of inner retinal layers was seen bounded posteriorly by the outer plexiform layer ...

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    19. Ophthalmic examination as a means to diagnose Subacute Sclerosing Panencephalitis: an optical coherence tomography and ultrawide field imaging evaluation

      Ophthalmic examination as a means to diagnose Subacute Sclerosing Panencephalitis: an optical coherence tomography and ultrawide field imaging evaluation

      Background Subacute sclerosing panencephalitis (SSPE) is a potentially fatal complication of measles. The authors report a case of recurrent myoclonic jerks under investigation, whose ophthalmic examination pointed to the diagnosis. Case presentation A 12-year-old boy with recurrent episodes of myoclonic jerks was found to have optic disc pallor and an irregular macular scar with pigmentation in the left eye. The retinal finding proved to be a strong diagnostic clue for SSPE. There was a history of exanthematous fever in childhood. Antibodies against measles were detected in both the cerebrospinal fluid and serum. Retinitis with intraretinal and subretinal hemorrhage in the ...

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    20. MOBILE SUBRETINAL CYSTICERCUS IMAGED BY SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY WITH MOTION TRACKER

      MOBILE SUBRETINAL CYSTICERCUS IMAGED BY SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY WITH MOTION TRACKER

      Purpose: To report optical coherence tomography-based videoimaging of alive subretinal cysticercus along with its mobile scolex. Methods: Spectral-domain optical coherence tomography was used to record high-definition videoimages, using the inbuilt motion tracker, in a 12-year-old boy with history of neurocysticercosis. Result: The scolex was found to be sensitive to light, and contractile movements were seen in the cyst wall and the germinative layers. The patient underwent vitrectomy, and the diagnoses were confirmed with histopathologic assessment. Conclusion: Optical coherence tomography is a useful tool for diagnosing posterior segment cysticercosis. The intense motion of scolex does not impact the surrounding ocular structures.

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    21. En Face Optical Coherence Tomography of Cystoid Macular Edema

      En Face Optical Coherence Tomography of Cystoid Macular Edema

      The honeycomb pattern of large and small cystoid abnormalities in the segmented en face swept-source optical coherence tomography (SS-OCT) section through the outer plexiform and inner nuclear layers of the retina is depicted in Figure , A. Intraretinal cystoid spaces in the conventional B-scan SS-OCT image are shown in Figure , B. The en face reconstruction demonstrates the exact nature, extent, and anatomical configuration of the pathology. Cystoid macular edema is a common sequela of intraocular inflammation resulting from many causes like intermediate uveitis and cataract surgery. The commercially available SS-OCT imaging technology has an axial resolution as high as 1 µm ...

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    22. Optical Coherence Tomography Angiography Study of Choroidal Neovascularization Associated With Focal Choroidal Excavation

      Optical Coherence Tomography Angiography Study of Choroidal Neovascularization Associated With Focal Choroidal Excavation

      The authors report the use of optical coherence tomography angiography (OCTA) (DRI OCT Triton; Topcon, Tokyo, Japan) to localize, characterize, and confirm the presence of a choroidal neovascular membrane in a patient of focal choroidal excavation (FCE) with recent-onset metamorphopsia and visual blurring. En face OCTA images just above the level of the retinal pigment epithelium-Bruch's membrane complex typically showed the presence of a glomerulus-like neovascular network with an adjacent dark area suggestive of a Type 2 choroidal neovascularization (CNV). OCTA was found to be a very useful, noninvasive, and quick imaging modality to detect secondary CNV formation in ...

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    23. Optical Coherence Tomography Angiography Imaging of Congenital Retinal Macrovessel

      Optical Coherence Tomography Angiography Imaging of Congenital Retinal Macrovessel

      Congenital retinal macrovessels (CRM) are rarely reported, aberrant, large branches of retinal vessels that can be both arteries and veins; however, they are more commonly veins that cross the horizontal raphe to either supply or drain the macula. In this brief report, the authors discuss optical coherence tomography angiography features of CRM in a 12-year-old male patient presenting with low visual acuity in the right eye since childhood. To the authors' knowledge, this is the first such report published in the literature.

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    24. Intraoperative Optical Coherence Tomography Imaging and Assessment of the Macula During Cataract Surgery: A Novel Technique

      Intraoperative Optical Coherence Tomography Imaging and Assessment of the Macula During Cataract Surgery: A Novel Technique

      The authors describe a technique to qualitatively analyze the posterior segment during cataract surgery using intraoperative optical coherence tomography (iOCT). Macular iOCT can be done before and after intraocular lens implantation after the media is rendered clear following phacoemulsification. A handheld irrigating planoconcave contact lens is placed over the cornea with the operating microscope in retroillumination mode. After focusing the microscope and upon getting a clear view of the posterior segment, iOCT is switched on, centered at the macula, and focused. This technique enables the surgeon to intraoperatively analyze and document the macular morphology and vitreoretinal interface. Potential uses of ...

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    25. Optical Coherence Tomography Follow-up of an Unusual Case of Old Rhegmatogenous Retinal Detachment With a Hemorrhagic Macrocyst at the Macula

      Optical Coherence Tomography Follow-up of an Unusual Case of Old Rhegmatogenous Retinal Detachment With a Hemorrhagic Macrocyst at the Macula

      A 32-year-old female presented with visual acuity of hand movement close to face, an old inferior rhegmatogenous retinal detachment (RRD), and a large hemorrhagic macular macrocyst (HMM) in the right eye. After 2 weeks of successful vitreoretinal surgery, the HMM started decreasing in height and resolved by 3 months. On optical coherence tomography, a zone of hyperreflectivity in the outer retinal layers was evident on resolution of the cyst. At final follow-up, the visual acuity improved to 1/60 only. Though HMM resolved completely after retinal reattachment, alteration and thickening of microarchitecture of the outer retinal layers ensued.

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    26. Optical Coherence Tomography Follow-up of an Unusual Case of Old Rhegmatogenous Retinal Detachment With a Hemorrhagic Macrocyst at the Macula

      Optical Coherence Tomography Follow-up of an Unusual Case of Old Rhegmatogenous Retinal Detachment With a Hemorrhagic Macrocyst at the Macula

      A 32-year-old female presented with visual acuity of hand movement close to face, an old inferior rhegmatogenous retinal detachment (RRD), and a large hemorrhagic macular macrocyst (HMM) in the right eye. After 2 weeks of successful vitreoretinal surgery, the HMM started decreasing in height and resolved by 3 months. On optical coherence tomography, a zone of hyperreflectivity in the outer retinal layers was evident on resolution of the cyst. At final follow-up, the visual acuity improved to 1/60 only. Though HMM resolved completely after retinal reattachment, alteration and thickening of microarchitecture of the outer retinal layers ensued.

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    1-26 of 26
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    Optical Coherence Tomography Follow-up of an Unusual Case of Old Rhegmatogenous Retinal Detachment With a Hemorrhagic Macrocyst at the Macula Optical Coherence Tomography Follow-up of an Unusual Case of Old Rhegmatogenous Retinal Detachment With a Hemorrhagic Macrocyst at the Macula Intraoperative Optical Coherence Tomography Imaging and Assessment of the Macula During Cataract Surgery: A Novel Technique Optical Coherence Tomography Angiography Imaging of Congenital Retinal Macrovessel Optical Coherence Tomography Angiography Study of Choroidal Neovascularization Associated With Focal Choroidal Excavation En Face Optical Coherence Tomography of Cystoid Macular Edema MOBILE SUBRETINAL CYSTICERCUS IMAGED BY SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY WITH MOTION TRACKER Ophthalmic examination as a means to diagnose Subacute Sclerosing Panencephalitis: an optical coherence tomography and ultrawide field imaging evaluation Omega Sign: A Distinct Optical Coherence Tomography Finding in Macular Combined Hamartoma of Retina and Retinal Pigment Epithelium Combined Hamartoma of the Retina and Retinal Pigment Epithelium: An Optical Coherence Tomography-Based Reappraisal Ageing and glaucoma progression of the retinal nerve fibre layer using spectral‐domain optical coherence tomography analysis Comparison of optical coherence tomography-guided versus intravascular ultrasound-guided percutaneous coronary intervention: Rationale and Design of a Randomized, controlled OCTIVUS trial