1. Articles from Amaury Badon

    1-4 of 4
    1. Remote scanning for ultra-large field of view in wide-field microscopy and full-field OCT

      Remote scanning for ultra-large field of view in wide-field microscopy and full-field OCT

      Imaging specimens over large scales and with a sub-micron resolution is instrumental to biomedical research. Yet, the number of pixels to form such an image usually exceeds the number of pixels provided by conventional cameras. While most microscopes are equipped with a motorized stage to displace the specimen and acquire the image tile-by-tile, we propose an alternative strategy that does not require any moving part in the sample plane. We propose to add a scanning mechanism in the detection unit of the microscope to collect sequentially different sub-areas of the field of view. Our approach, called remote scanning, is compatible ...

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    2. Distortion matrix concept for deep imaging in optical coherence microscopy

      Distortion matrix concept for deep imaging in optical coherence microscopy

      In optical imaging, light propagation is affected by the inhomogeneities of the medium. Sample-induced aberrations and multiple scattering can strongly degrade the image resolution and contrast. Based on a dynamic correction of the incident and/or reflected wave-fronts, adaptive optics has been employed to compensate for those aberrations. However, it mainly applies to spatiallyinvariant aberrations or to thin aberrating layers. Here, we propose a global and non-invasive approach based on the distortion matrix concept. This matrix basically connects any focusing point of the image with the distorted part of its wave-front in reflection. A time-reversal and entropy analysis of the ...

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    3. The multiple scattering limit in optical microscopy

      The multiple scattering limit in optical microscopy

      Optical microscopy offers a unique insight of biological structures with a sub-micrometer resolution and a minimum invasiveness. However, the inhomogeneities of the specimen itself can induce multiple scattering of light and optical aberrations which limit the observation to depths close to the surface. To predict quantitatively the penetration depth in microscopy, we theoretically derive the single-to-multiple scattering ratio in reflection. From this key quantity, the multiple scattering limit is deduced for various microscopic imaging techniques such as confocal microscopy, optical coherence tomography and related methods.

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    4. Smart optical coherence tomography for ultra-deep imaging through highly scattering media

      Smart optical coherence tomography for ultra-deep imaging through highly scattering media

      Multiple scattering of waves in disordered media is a nightmare whether it be for detection or imaging purposes. The best approach so far to get rid of multiple scattering is optical coherence tomography. It basically combines confocal microscopy and coherence time-gating to discriminate ballistic photons from a predominant multiple scattering background. Nevertheless, the imaging depth range remains limited to 1 mm at best in human soft tissues. Here we propose a matrix approach of optical imaging to push back this fundamental limit. By combining a matrix discrimination of ballistic waves and iterative time-reversal, we show both theoretically and experimentally an ...

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    1-4 of 4
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  2. Topics in the News

    1. (2 articles) ESPCI ParisTech
    2. (2 articles) Claude Boccara
    3. (1 articles) Mathias Fink
    4. (1 articles) Tsinghua University
    5. (1 articles) Universidade Federal de São Paulo
    6. (1 articles) Carl Zeiss Meditec
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