1. Articles from Andrea Cogliati

    1-5 of 5
    1. In vivo imaging of corneal nerves and cellular structures in mice with Gabor-domain optical coherence microscopy

      In vivo imaging of corneal nerves and cellular structures in mice with Gabor-domain optical coherence microscopy

      Gabor-domain optical coherence microscopy (GDOCM) demonstrated in vivo corneal imaging with cellular resolution and differentiation in mice over a field of view of 1 mm 2 . Contact and non-contact imaging was conducted on six healthy and six hyperglycemic C57BL/6J mice. Cellular resolution in the 3D GDOCM images was achieved after motion correction. Corneal nerve fibers were traced and their lengths and branches calculated. Noncontact, label-free imaging of corneal nerves has clinical utility in health and disease, and in transplant evaluation. To the authors’ knowledge, this is the first report of in vivo 3D corneal imaging in mice with the ...

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    2. 3D wide field-of-view Gabor-domain optical coherence microscopy advancing real-time in-vivo imaging and metrology

      3D wide field-of-view Gabor-domain optical coherence microscopy advancing real-time in-vivo imaging and metrology

      Real-time volumetric high-definition wide-field-of-view in-vivo cellular imaging requires micron-scale resolution in 3D. Compactness of the handheld device and distortion-free images with cellular resolution are also critically required for onsite use in clinical applications. By integrating a custom liquid lens-based microscope and a dual-axis MEMS scanner in a compact handheld probe, Gabor-domain optical coherence microscopy (GD-OCM) breaks the lateral resolution limit of optical coherence tomography through depth, overcoming the tradeoff between numerical aperture and depth of focus, enabling advances in biotechnology. Furthermore, distortion-free imaging with no post-processing is achieved with a compact, lightweight handheld MEMS scanner that obtained a 12-fold reduction ...

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    3. MEMS-based handheld scanning probe with pre-shaped input signals for distortion-free images in Gabor-domain optical coherence microscopy

      MEMS-based handheld scanning probe with pre-shaped input signals for distortion-free images in Gabor-domain optical coherence microscopy

      High-speed scanning in optical coherence tomography (OCT) often comes with either compromises in image quality, the requirement for post-processing of the acquired images, or both. We report on distortion-free OCT volumetric imaging with a dual-axis micro-electro-mechanical system (MEMS)-based handheld imaging probe. In the context of an imaging probe with optics located between the 2D MEMS and the sample, we report in this paper on how pre-shaped open-loop input signals with tailored non-linear parts were implemented in a custom control board and, unlike the sinusoidal signals typically used for MEMS, achieved real-time distortion-free imaging without post-processing. The MEMS mirror was ...

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    4. Gabor-domain optical coherence microscopy with integrated dual-axis MEMS scanner for fast 3D imaging and metrology

      Gabor-domain optical coherence microscopy with integrated dual-axis MEMS scanner for fast 3D imaging and metrology

      Fast, robust, nondestructive 3D imaging is needed for characterization of microscopic structures in industrial and clinical applications. A custom micro-electromechanical system (MEMS)-based 2D scanner system was developed to achieve 55 kHz A-scan acquisition in a Gabor-domain optical coherence microscopy (GD-OCM) instrument with a novel multilevel GPU architecture for high-speed imaging. GD-OCM yields high-definition volumetric imaging with dynamic depth of focusing through a bio-inspired liquid lens-based microscope design, which has no moving parts and is suitable for use in a manufacturing setting or in a medical environment. A dual-axis MEMS mirror was chosen to replace two single-axis galvanometer mirrors; as ...

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    1-5 of 5
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  2. Topics in the News

    1. (6 articles) National Institutes of Health
    2. (5 articles) University of Rochester
    3. (5 articles) Jannick P. Rolland
    4. (3 articles) UCLA
    5. (2 articles) UC Irvine
    6. (2 articles) Oregon Health & Science University
    7. (2 articles) Zhongping Chen
    8. (2 articles) Yifan Jian
    9. (1 articles) Kevin P. Thompson
    10. (1 articles) Virgil-Florin Duma
    11. (1 articles) UCLA
    12. (1 articles) University of L├╝beck
    13. (1 articles) Pusan National University
    14. (1 articles) Evelyn Regar
    15. (1 articles) Antonios Karanasos
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    Gabor-domain optical coherence microscopy with integrated dual-axis MEMS scanner for fast 3D imaging and metrology MEMS-based handheld scanning probe with pre-shaped input signals for distortion-free images in Gabor-domain optical coherence microscopy 3D wide field-of-view Gabor-domain optical coherence microscopy advancing real-time in-vivo imaging and metrology Gabor-Domain Optical Coherence Tomography to Aid in Mohs Resection of Basal Cell Carcinoma In vivo imaging of corneal nerves and cellular structures in mice with Gabor-domain optical coherence microscopy The Effect of Anti-Tubercular Drugs on Retinal Nerve Fiber Layer Thickness Using Optical Coherence Tomography A Cross-sectional Optical Coherence Tomography Study in Patients on Taxane-based Therapy and A Case Report with the Literature Review Association of systemic inflammatory biomarkers with morphological characteristics of the coronary atherosclerotic plaque by intravascular optical coherence tomography. OCT angiography improves views of retina blood flow Real-time retinal layer segmentation of OCT Volumes with GPU and Deep learning Baylor College of Medicine Receives a 2020 NIH Grant for Biomechanics of Early Mammalian Cardiogenesis University of Houston Receives a 2020 NIH Grant for Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality