1. Articles from Andrea Cogliati

    1-4 of 4
    1. 3D wide field-of-view Gabor-domain optical coherence microscopy advancing real-time in-vivo imaging and metrology

      3D wide field-of-view Gabor-domain optical coherence microscopy advancing real-time in-vivo imaging and metrology

      Real-time volumetric high-definition wide-field-of-view in-vivo cellular imaging requires micron-scale resolution in 3D. Compactness of the handheld device and distortion-free images with cellular resolution are also critically required for onsite use in clinical applications. By integrating a custom liquid lens-based microscope and a dual-axis MEMS scanner in a compact handheld probe, Gabor-domain optical coherence microscopy (GD-OCM) breaks the lateral resolution limit of optical coherence tomography through depth, overcoming the tradeoff between numerical aperture and depth of focus, enabling advances in biotechnology. Furthermore, distortion-free imaging with no post-processing is achieved with a compact, lightweight handheld MEMS scanner that obtained a 12-fold reduction ...

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    2. MEMS-based handheld scanning probe with pre-shaped input signals for distortion-free images in Gabor-domain optical coherence microscopy

      MEMS-based handheld scanning probe with pre-shaped input signals for distortion-free images in Gabor-domain optical coherence microscopy

      High-speed scanning in optical coherence tomography (OCT) often comes with either compromises in image quality, the requirement for post-processing of the acquired images, or both. We report on distortion-free OCT volumetric imaging with a dual-axis micro-electro-mechanical system (MEMS)-based handheld imaging probe. In the context of an imaging probe with optics located between the 2D MEMS and the sample, we report in this paper on how pre-shaped open-loop input signals with tailored non-linear parts were implemented in a custom control board and, unlike the sinusoidal signals typically used for MEMS, achieved real-time distortion-free imaging without post-processing. The MEMS mirror was ...

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    3. Gabor-domain optical coherence microscopy with integrated dual-axis MEMS scanner for fast 3D imaging and metrology

      Gabor-domain optical coherence microscopy with integrated dual-axis MEMS scanner for fast 3D imaging and metrology

      Fast, robust, nondestructive 3D imaging is needed for characterization of microscopic structures in industrial and clinical applications. A custom micro-electromechanical system (MEMS)-based 2D scanner system was developed to achieve 55 kHz A-scan acquisition in a Gabor-domain optical coherence microscopy (GD-OCM) instrument with a novel multilevel GPU architecture for high-speed imaging. GD-OCM yields high-definition volumetric imaging with dynamic depth of focusing through a bio-inspired liquid lens-based microscope design, which has no moving parts and is suitable for use in a manufacturing setting or in a medical environment. A dual-axis MEMS mirror was chosen to replace two single-axis galvanometer mirrors; as ...

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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) University of Rochester
    2. (4 articles) Jannick P. Rolland
    3. (3 articles) UCLA
    4. (1 articles) Kevin P. Thompson
    5. (1 articles) Virgil-Florin Duma
    6. (1 articles) Tufts University
    7. (1 articles) Sungkyunkwan University
    8. (1 articles) University College London
    9. (1 articles) Massachusetts Institute of Technology
    10. (1 articles) Jay S. Duker
    11. (1 articles) Colin Hopper
    12. (1 articles) James G. Fujimoto
    13. (1 articles) Andre J. Witkin
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    15. (1 articles) Mark E. Brezinski
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    Gabor-domain optical coherence microscopy with integrated dual-axis MEMS scanner for fast 3D imaging and metrology MEMS-based handheld scanning probe with pre-shaped input signals for distortion-free images in Gabor-domain optical coherence microscopy 3D wide field-of-view Gabor-domain optical coherence microscopy advancing real-time in-vivo imaging and metrology Gabor-Domain Optical Coherence Tomography to Aid in Mohs Resection of Basal Cell Carcinoma Remote scanning for ultra-large field of view in wide-field microscopy and full-field OCT Inadequate Intimal Angiogenesis as a Source of Coronary Plaque Instability Comparison of optical coherence tomography angiography results of adult patients with Familial Mediterranean fever and healthy individuals Intravascular ultrasound or optical coherence tomography-defined anatomic severity and hemodynamic severity assessed by coronary physiologic indices Optical coherence tomography in the assessment of cutaneous cancer margins of the face: an immediate ex vivo study Global Analysis of Macular Choriocapillaris Perfusion in Dry Age-Related Macular Degeneration using Swept-Source Optical Coherence Tomography Angiography Reliability of foveal avascular zone metrics automatically measured by Cirrus optical coherence tomography angiography in healthy subjects Duke University Engineering Professor Sina Farsiu Elected Fellow of the IEEE