1. Articles from Abhilash Goud

    1-12 of 12
    1. Angiographic features of polypoidal choroidal vasculopathy using indocyanine green angiography and optical coherence tomography angiography: A comparative study

      Angiographic features of polypoidal choroidal vasculopathy using indocyanine green angiography and optical coherence tomography angiography: A comparative study

      Background: To compare the vascular lesion size using optical coherence tomography angiography and indocyanine green angiography in eyes with polypoidal choroidal vasculopathy. Methods: Treatment-naïve cases (46 eyes of 44 patients) with polypoidal choroidal vasculopathy were retrospectively analyzed. The comparison of mean area of branching vascular network and polyp detection rate was done between indocyanine green angiography and optical coherence tomography angiography and correlated with various optical coherence tomography features. Results: The mean age of the study patients was 62.33 ± 10.74 years. The mean branching vascular network size was 7.47 ± 5.74 and 7.51 ± 5.69 ...

      Read Full Article
    2. Choroidal Vascularity Index Using Swept-Source and Spectral-Domain Optical Coherence Tomography: A Comparative Study

      Choroidal Vascularity Index Using Swept-Source and Spectral-Domain Optical Coherence Tomography: A Comparative Study

      BACKGROUND AND OBJECTIVE: Choroidal vascularity index (CVI) is a noninvasive tool to assess choroidal structure. The objective of the current study was to compare the CVI measurements on swept-source optical coherence tomography (SS-OCT) and spectral-domain OCT (SD-OCT) scans using the same image binarization protocol. PATIENTS AND METHODS: This prospective study was conducted from July 2016 through January 2017 and involved 54 healthy volunteers at a tertiary referral eye care institute in Southern India. Choroidal scans were obtained using both SS- and SD-OCT machines. An automated binarization algorithm was used to compute CVI. RESULTS: The mean CVI with SS-OCT scans was ...

      Read Full Article
    3. Choroidal imaging biomarkers

      Choroidal imaging biomarkers

      The choroid is the vascular coat of the eye,and its role has been studied in multiple chorioretinal disorders. The recent advancements in choroidal imaging techniques including enhanced depth imaging optical coherence tomography (EDI-OCT), swept source (SS-OCT), enface OCT and OCT angiography have facilitated an in-depth analysis of choroid. The gradual shift from manual to automated segmentation and binarization methods have led to precise and reproducible measurements of choroidal parameters. These qualitative and quantitative parameters, called choroidal imaging biomarkers, have evolved over the past decade from a simple linear subfoveal choroidal thickness to more complex 3 dimensional (3-D) choroidal reconstruction ...

      Read Full Article
    4. Optical coherence tomography angiography in acute unilateral nonarteritic anterior ischemic optic neuropathy: A comparison with the fellow eye and with eyes with papilledema

      Optical coherence tomography angiography in acute unilateral nonarteritic anterior ischemic optic neuropathy: A comparison with the fellow eye and with eyes with papilledema

      Purpose: The purpose of this study is to detect the optic nerve head (ONH) and peripapillary perfusion in eyes with acute nonarteritic anterior ischemic optic neuropathy (NAION) compared to the fellow normal eyes using optical coherence tomography angiography (OCTA) and to compare with nonischemic disc edema (papilledema). Methods: Retrospective analysis of patients with unilateral NAION who underwent OCTA was performed. All patients underwent comprehensive ocular examination including visual field testing. ONH was imaged using 6 mm × 6 mm scan by Topcon DRI Triton ® OCT system. Vascularity loss was analyzed using ImageJ software in diseased eyes in comparison to normal fellow ...

      Read Full Article
    5. Comparison of choroidal vessel thickness in children and adult eyes by enhanced-depth imaging optical coherence tomography imaging

      Comparison of choroidal vessel thickness in children and adult eyes by enhanced-depth imaging optical coherence tomography imaging

      AIM : To evaluate choroidal thickness, medium choroidal vessel thickness (MCVT) and large choroidal vessel thickness (LCVT) in normal children and adult subjects. METHODS : Manual measurements of subfoveal choroidal thickness (SFCT), MCVT and LCVT at subfoveal and 750 μm nasal and temporal to fovea locations were completed on enhanced-depth imaging optical coherence tomography (EDI-OCT) scans of normal children and adult subjects. RESULTS : Fifty adult and fifty-seven child subjects were included in the study (including 80 adult and 103 child eyes). Mean (±SD) SFCT of adult and children eyes in the study was 309.3±95.7 μm and 279.3±50 ...

      Read Full Article
    6. Quantitative shadow compensated optical coherence tomography of choroidal vasculature

      Quantitative shadow compensated optical coherence tomography of choroidal vasculature

      Conventionally rendered optical coherence tomography (OCT) images of the posterior segment contain shadows which influence the visualization of deep structures such as the choroid. The purpose of this study was to determine whether OCT shadow compensation (SC) alters the appearance of the choroid and the apparent choroidal vascularity index (CVI), an OCT-derived estimated ratio of luminal to total choroidal volume. All scans were shadow compensated using a previously published algorithm, binarized using a novel validated algorithm and extracted binarized choroid to estimate CVI. On 27 raw swept-source OCT volume-scans of healthy subjects, the effect of SC on CVI was established ...

      Read Full Article
      Mentions: K. Bailey Freund
    7. Segmentation errors in macular ganglion cell analysis as determined by optical coherence tomography in eyes with macular pathology

      Segmentation errors in macular ganglion cell analysis as determined by optical coherence tomography in eyes with macular pathology

      Background To evaluate artifacts in macular ganglion cell inner plexiform layer (GCIPL) thickness measurement in eyes with retinal pathology using spectral-domain optical coherence tomography (SD OCT). Methods Retrospective analysis of color-coded maps, infrared images and 128 horizontal B-scans (acquired in the macular ganglion cell inner plexiform layer scans), using the Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA). The study population included 105 eyes with various macular conditions compared to 30 eyes of 30 age-matched healthy volunteers. The overall frequency of image artifacts and the relative frequency of artifacts were stratified by macular disease. Results Scan errors and artifacts were found ...

      Read Full Article
    8. Influence of scanning area on choroidal vascularity index measurement using optical coherence tomography

      Influence of scanning area on choroidal vascularity index measurement using optical coherence tomography

      Purpose Recently, choroidal vascularity index (CVI) is proposed as a novel tool to evaluate the choroidal vasculature. In this study, we investigate the impact of scanning area on CVI measurement using spectral-domain optical coherence tomography (SD-OCT). Methods Spectral-domain optical coherence tomography (SD-OCT) using enhanced depth imaging mode was performed in 30 eyes from 15 normal subjects. Three scanning areas were compared: dingle foveal scan; central macular scans [scan passing through central 1000 microns circle on Early Treatment Diabetic Retinopathy Study (ETDRS) grid, inner circle]; and total macular cube scans. Binarization of OCT B-scans and segmentation of the binarized choroid layer ...

      Read Full Article
    9. Subfoveal Choroidal Vascularity in Myopia: Evidence From Spectral-Domain Optical Coherence Tomography

      Subfoveal Choroidal Vascularity in Myopia: Evidence From Spectral-Domain Optical Coherence Tomography

      BACKGROUND AND OBJECTIVE: To evaluate subfoveal choroidal vascularity in eyes with myopia in comparison to age-matched healthy subjects. PATIENTS AND METHODS: Retrospective analysis of single foveal enhanced depth imaging optical coherence tomography (EDI-OCT) scans of 30 eyes with myopia (axial length greater than 25 mm). Subfoveal choroidal vascularity was evaluated by calculating vessel-area-to-stromal-area ratio using a previously validated automated algorithm. RESULTS: The subfoveal stromal area was significantly smaller in myopes (0.95 mm 3 ± 0.22 mm 3 ) compared to controls (1.33 mm 3 ± 0.23 mm 3 ; P < .0001). However, there was no significant difference in vascular area ...

      Read Full Article
    10. AGE-RELATED CHANGES IN CHOROIDAL VASCULAR DENSITY OF HEALTHY SUBJECTS BASED ON IMAGE BINARIZATION OF SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY

      AGE-RELATED CHANGES IN CHOROIDAL VASCULAR DENSITY OF HEALTHY SUBJECTS BASED ON IMAGE BINARIZATION OF SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY

      Purpose: To analyze the vascular density of the choroid in a healthy population using swept-source optical coherence tomography. Methods: A cross-sectional, noninterventional study. Inclusion criteria: best-corrected visual acuity between 20/20 and 20/25, spherical equivalent between +/-3 diopters, no systemic or ocular diseases, and ages ranging between 3 and 85 years. One hundred and thirty-six eyes from 136 subjects were analyzed, 86 eyes (63.2%) were from male and 50 eyes (36.8%) from female subjects. The eyes were divided into different age groups to analyze the possible age-related changes. Twelve-millimeter horizontal, fovea-centered B-scans were used. Choroidal stroma and ...

      Read Full Article
    11. Prevalence and Distribution of Segmentation Errors in Macular Ganglion Cell Analysis of Healthy Eyes Using Cirrus HD-OCT

      Prevalence and Distribution of Segmentation Errors in Macular Ganglion Cell Analysis of Healthy Eyes Using Cirrus HD-OCT

      Purpose To determine the frequency of different types of spectral domain optical coherence tomography (SD-OCT) scan artifacts and errors in ganglion cell algorithm (GCA) in healthy eyes. Methods Infrared image, color-coded map and each of the 128 horizontal b-scans acquired in the macular ganglion cell-inner plexiform layer scans using the Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA) macular cube 512 × 128 protocol in 30 healthy normal eyes were evaluated. The frequency and pattern of each artifact was determined. Deviation of the segmentation line was classified into mild (less than 10 microns), moderate (10–50 microns) and severe (more than 50 ...

      Read Full Article
    12. Neurodegeneration in Type 2 Diabetes: Evidence From Spectral-Domain Optical Coherence Tomography

      Neurodegeneration in Type 2 Diabetes: Evidence From Spectral-Domain Optical Coherence Tomography

      Purpose : The purpose of this study was to assess changes in the neural retina in eyes with different stages of diabetic retinopathy (DR) in comparison to age-matched healthy subjects. Methods : Retrospective analysis of spectral-domain optical coherence tomography (SD-OCT) scans of 76 naïve eyes of 62 subjects with diabetes was performed. Key exclusion criteria included presence of diabetic macular edema, any other retinal disease, history of any treatment for DR, or incorrect segmentation of the retinal layers on SD-OCT scans. Eyes from diabetic patients were divided into three groups, including no DR, nonproliferative DR (NPDR), and proliferative DR (PDR). A ...

      Read Full Article
    1-12 of 12
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (5 articles) L V Prasad Eye Institute
    2. (2 articles) Carl Zeiss Meditec
    3. (1 articles) Harsha L. Rao
    4. (1 articles) K. Bailey Freund
    5. (1 articles) Giulio Barteselli
    6. (1 articles) Topcon Medical Systems
  3. Popular Articles

  4. Picture Gallery

    Neurodegeneration in Type 2 Diabetes: Evidence From Spectral-Domain Optical Coherence Tomography Prevalence and Distribution of Segmentation Errors in Macular Ganglion Cell Analysis of Healthy Eyes Using Cirrus HD-OCT AGE-RELATED CHANGES IN CHOROIDAL VASCULAR DENSITY OF HEALTHY SUBJECTS BASED ON IMAGE BINARIZATION OF SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY Subfoveal Choroidal Vascularity in Myopia: Evidence From Spectral-Domain Optical Coherence Tomography Influence of scanning area on choroidal vascularity index measurement using optical coherence tomography Segmentation errors in macular ganglion cell analysis as determined by optical coherence tomography in eyes with macular pathology Quantitative shadow compensated optical coherence tomography of choroidal vasculature Comparison of choroidal vessel thickness in children and adult eyes by enhanced-depth imaging optical coherence tomography imaging Optical coherence tomography angiography in acute unilateral nonarteritic anterior ischemic optic neuropathy: A comparison with the fellow eye and with eyes with papilledema Choroidal Vascularity Index Using Swept-Source and Spectral-Domain Optical Coherence Tomography: A Comparative Study Postdoctoral Associate Position at Duke Vision and Image Processing Laborator Anterior segment optical coherence tomography angiography