1. Articles from L. B. Snopova

    1-5 of 5
    1. Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study

      Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study

      Determining boundaries of infiltrative glial tumors remains a challenging problem in neurooncology. Optical coherence tomography (OCT) with cross-polarization (CP) visualization is a promising technique as a surgical guidance tool. However, the outcome of the procedures performed under OCT guidance strongly depends on the surgeon’s qualification. Thus, a quantitative method for assessing resection margins with OCT is required. The aim of this study was to develop a robust quantitative approach for CP OCT data to differentiate tumorous from non-tumorous tissues in a rat glioma model. Materials and Methods. The study was carried out on the rats’ brains (n=6) with ...

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    2. The Development of the Methodology of Monitoring Experimental Tumors Using Multimodal Optical Coherence Tomography: the Choice of an Optimal Tumor Model

      The Development of the Methodology of Monitoring Experimental Tumors Using Multimodal Optical Coherence Tomography: the Choice of an Optimal Tumor Model

      The objective of the research was to study the features of transplantation, growth and visualization of experimental tumors of animals, using multi-functional optical coherence tomography (OCT) to develop the methodology of evaluation of individual tumor response to anti-cancer therapy. Materials and Methods. The research was carried out using an experimental high-speed spectral-domain multimodal OCT system developed at the Institute of Applied Physics of the Russian Academy of Sciences (Russia). The technical characteristics of the system are the following: speed of information acquisition, 20,000 А-scans per second; 1.3 μm wavelength; frame size, approximately 4×2 mm; lateral resolution, 25 ...

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    3. Comparative studies of infrared laser and radio-frequency action on in vitro biotissues by the method of polarization sensitive optical coherence tomography

      Comparative studies of infrared laser and radio-frequency action on in vitro biotissues by the method of polarization sensitive optical coherence tomography
      We make comparative studies of structural changes of in vitro biotissues subject to the infrared (IR) laser radiation and the radio-frequency field. Noninvasive diagnostics and monitoring of microstructural changes of biological tissues are performed using optical coherent tomography.
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    4. Advantages of cross-polarization endoscopic optical coherence tomography in diagnosis of bladder neoplasia

      Advantages of cross-polarization endoscopic optical coherence tomography in diagnosis of bladder neoplasia
      We consider the cross-polarization OCT (CP OCT) that is focused on comparison of images resulting from cross-polarization and co-polarization scattering simultaneously. This technique provides information about microstructural and biochemical alterations in depolarizing tissue components (collagen). We found that mature type I collagen gives a strong signal in orthogonal polarization. CP OCT images of benign inflammatory processes always feature signal in orthogonal polarization, with layers and borders persisting to be well defined. In the presence of precancerous alterations, signal in orthogonal polarization is available in the image but it is irregular, disappearing in some areas. A CP OCT image of bladder ...
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    5. Cross-polarization endoscopic optical coherence tomography in urology

      Cross-polarization endoscopic optical coherence tomography in urology
      We present results obtained using a two-channel portable device for CP OCT based on the polarization-maintaining fiber. The device is capable of acquiring OCT images of the object in direct and orthogonal polarizations simultaneously. The OCT system has an endoscopic forward-looking probe (2.7 mm in diameter). The CP OCT imaging was done in 64 postoperative specimens, for 30 patients during cystoscopy with suspicion of urothelial neoplasia, and for 11 patients with prostatectomy due to cancer. After surgery in the tissue specimen we immediately introduced surgical suture and investigated a bladder wall by CP OCT. When comparing OCT images and ...
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    1-5 of 5
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  2. Topics in the News

    1. (5 articles) Institute of Applied Physics
    2. (4 articles) Nizhny Novgorod State Medical Academy
    3. (4 articles) Natalia D. Gladkova
    4. (3 articles) Elena V. Zagaynova
    5. (2 articles) University of Toronto
    6. (2 articles) Olga S. Streltsova
    7. (2 articles) Valentin M. Gelikonov
    8. (2 articles) Elena B. Kiseleva
    9. (2 articles) Maria M. Karabut
    10. (2 articles) I. Alex Vitkin
    11. (1 articles) UC Davis
    12. (1 articles) Robert J. Zawadzki
    13. (1 articles) Mehdi Azimipour
    14. (1 articles) John S. Werner
    15. (1 articles) Ravi S. Jonnal
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    Cross-polarization endoscopic optical coherence tomography in urology Advantages of cross-polarization endoscopic optical coherence tomography in diagnosis of bladder neoplasia Comparative studies of infrared laser and radio-frequency action on in vitro biotissues by the method of polarization sensitive optical coherence tomography The Development of the Methodology of Monitoring Experimental Tumors Using Multimodal Optical Coherence Tomography: the Choice of an Optimal Tumor Model Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study Optoretinography: optical measurements of human cone and rod photoreceptor responses to light Nodular skin lesions: correlation of reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) features OCT and Ophthalmology in the Age of Artificial Intelligence, Tuesday Oct 8, 2019 1:00P EDT Compensation for the Influence of Fluctuations in the Distance to the Object During Noncontact Probing in Spectral Domain Optical Coherence Tomography Pattern electroretinogram changes in patients with primary open-angle glaucoma in correlation with visual field and optical coherence tomography changes Objective evaluation of proliferative diabetic retinopathy using optical coherence tomography Repeatability of Cornea and Sublayer Thickness Measurements Using Optical Coherence Tomography in Corneas of Anomalous Refractive Status