1. Articles from Cha-Min Tang

    1-7 of 7
    1. Coherence gated doppler motion sensor and medical applications

      Coherence gated doppler motion sensor and medical applications

      A motion sensor applicable to medical procedures includes a source of light with a wavelength bandwidth and an optical detector. A first optical coupler terminates in a first probe tip and couples the light into the first probe tip. A second optical coupler terminates in a second probe tip and directs onto the detector scattered light returning through the second probe tip. A presentation device outputs a signal that indicates motion in a target volume of a sample in a vicinity of the probe tips based on a Doppler shift of the scattered light. The volume depends on coherence distance ...

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    2. Coherence-gated Doppler: a fiber sensor for precise localization of blood flow

      Coherence-gated Doppler: a fiber sensor for precise localization of blood flow

      Miniature optical sensors that can detect blood vessels in front of advancing instruments will significantly benefit many interventional procedures. Towards this end, we developed a thin and flexible coherence-gated Doppler (CGD) fiber probe (O.D. = 0.125 mm) that can be integrated with minimally-invasive tools to provide real-time audio feedback of blood flow at precise locations in front of the probe. Coherence-gated Doppler (CGD) is a hybrid technology with features of laser Doppler flowmetry (LDF) and Doppler optical coherence tomography (DOCT). Because of its confocal optical design and coherence-gating capabilities, CGD provides higher spatial resolution than LDF. And compared to ...

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    3. Endoscopic Microscopy Using Optical Coherence Tomography

      Endoscopic Microscopy Using Optical Coherence Tomography

      Optical coherence tomography (OCT) can perform high-speed, micron-level high resolution imaging of tissue microstructures in vivo and in real time and can function as a type of optical biopsy to visualize the structural and functional alterations associated with various diseases. The advances in endoscopic OCT and optical coherence microscopy (OCM) provide an exciting avenue for many promising clinical applications with the potential of enhancing diagnostic capabilities and treatment efficacies. In this review paper, we first review the basic principles for time- and Fourierdomain OCT. We then survey the various endoscopic OCT technologies followed by the review of several representative clinical ...

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    4. Congratulations to Chia-Pin Liang From the University of Maryland a Winner of a 2012 Student Travel Grant Award

      Congratulations to Chia-Pin Liang From the University of Maryland a Winner of a 2012 Student Travel Grant Award
      Chia-Pin Liang from the University of Maryland is one of four winners of the OCT News 2012 student travel grant awards (see prior announcement Here). Below is a summary of his work. Stereotactic procedures that require insertion of needle-based instruments into the brain serve important roles in a variety of neurosurgical interventions such as biopsy, catheterization, and electrode placement. The laceration of blood vessels in the path of the advancing needle can result in stroke and even death and is perhaps the most worried complication. Also, the brain may shift during surgery because of cerebrospinal fluid (CSF) leakage so that ...
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    5. A forward-imaging needle-type OCT probe for image guided stereotactic procedures

      A forward-imaging needle-type OCT probe for image guided stereotactic procedures
      A forward-imaging needle-type optical coherence tomography (OCT) probe with Doppler OCT (DOCT) capability has the potential to solve critical challenges in interventional procedures. A case in point is stereotactic neurosurgery where probes are advanced into the brain based on predetermined coordinates. Laceration of blood vessels in front of the advancing probe is an unavoidable complication with current methods. Moreover, cerebrospinal fluid (CSF) leakage during surgery can shift the brain rendering the predetermined coordinates unreliable. In order to address these challenges, we developed a forward-imaging OCT probe (740 μm O.D.) using a gradient-index (GRIN) rod lens that can provide real-time ...
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    6. Optical coherence tomography guided neurosurgical procedures in small rodents

      The delivery of therapeutic agents directly to targets deep within the brain is becoming an important tool in the treatment of a variety of neurological disorders. Currently, the standard method to accomplish this is by using stereotactic procedures. While this existing method is adequate for many experimental situations, it is essentially a blind procedure that cannot provide real-time feedback on whether the actual location deviated from the intended location or whether the therapeutic agent was actually delivered. Here we describe an optical guidance technique that is designed to work in conjunction with existing stereotactic procedures to provide the needed real-time ...
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    7. Thinking inside the graft: applications of optical coherence tomography in coronary artery bypass grafting

      Emile N. Brown, Nicholas S. Burris, Junyan Gu et al. Recent advances in catheter-based optical coherence tomography (OCT) have provided the necessary resolution and acquisition speed for high-quality intravascular imaging. Complications associated with clearing blood from the vessel of a living patient have prevented its wider acceptance. We identify ... [J. Biomed. Opt. 12, 051704 (2007)] published Wed Oct 24, 2007.
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    1-7 of 7
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  2. Topics in the News

    1. (6 articles) University of Maryland
    2. (3 articles) Abbott
    3. (1 articles) Boston University
    4. (1 articles) San Raffaele Scientfic Institute
    5. (1 articles) Carl Zeiss Meditec
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    A forward-imaging needle-type OCT probe for image guided stereotactic procedures Congratulations to Chia-Pin Liang From the University of Maryland a Winner of a 2012 Student Travel Grant Award Endoscopic Microscopy Using Optical Coherence Tomography Coherence-gated Doppler: a fiber sensor for precise localization of blood flow Coherence gated doppler motion sensor and medical applications Intraoperative Optical Coherence Tomography in Idiopathic Macular Epiretinal Membrane Surgery Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives Non-cystic macular thickening on optical coherence tomography as an alternative to fluorescein angiography for predicting retinal vascular leakage in early stages of uveitis Self-supervised patient-specific features learning for OCT image classification Accurate In Vivo Bowman's Thickness Measurement Using Mirau Ultrahigh Axial Resolution Line Field Optical Coherence Tomography Optical coherence tomography reveals retinal thinning in schizophrenia spectrum disorders Longitudinal Evaluation of Changes in Retinal Architecture Using Optical Coherence Tomography in Achromatopsia