1. Articles from Jingyu Wang

    1-7 of 7
    1. A Baseline Study of Oxygen Saturation in Parafoveal Vessels Using Visible Light Optical Coherence Tomography

      A Baseline Study of Oxygen Saturation in Parafoveal Vessels Using Visible Light Optical Coherence Tomography

      The retinal macula is at the center of our visual field, and thus pathological damage in the macula significantly impacts an individual's quality of life. The parafoveal vessels form the inner retina provide oxygen perfusion, and the measurement of parafoveal oxygen saturation (sO 2 ) can evaluate macular metabolism and provide pathophysiological insight. In this paper, for the first time, we present a baseline study of microvascular oxygen saturation (sO 2 ) in perifoveal macular region using visible light optical coherence tomography (VIS-OCT) on normal eyes. The arterial and venous sO 2 from all eyes was 92.1 ± 7.1 (vol ...

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    2. Simultaneous visible light optical coherence tomography and near infrared OCT angiography in retinal pathologies: A case study

      Simultaneous visible light optical coherence tomography and near infrared OCT angiography in retinal pathologies: A case study

      A dual-channel optical coherence tomography system with wavelengths in the visible and near-infrared light ranges can provide both structural and functional information for retinal microvasculature simultaneously. We applied this integrated system in an ongoing clinical study of patients with various retinal pathologies. Here, we present case study results of patients with diabetic retinopathy, central retinal vein occlusion, and sickle cell retinopathy compared to a healthy subject. For the first time, this comparison validates the system's ability to detect structural anomalies in both en face and B-scan images with simultaneous retinal optical coherence tomography angiography and measurement of sO 2 ...

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    3. Full-field optical coherence tomography apply in sphere measurements

      Full-field optical coherence tomography apply in sphere measurements

      The geometry of a spherical surface, for example that of a precision optic, is completely determined by the radius –of-curvature at one point and the deviation from the perfect spherical form at all other points of the sphere. Full-field Optical Coherence Tomography (FF-OCT) is a parallel detection OCT technique that utilizes a 2D detector array. This technique avoids mechanical scanning in imaging optics, thereby speeding up the imaging process and enhancing the quality of images. The current paper presents an FF-OCT instrument that is designed to be used in sphere measurement with the principle of multiple delays (MD) OCT to ...

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    4. Feature of the Week 05/08/2016: Complex Master Slave Interferometry

      Feature of the Week 05/08/2016: Complex Master Slave Interferometry

      A general theoretical model is developed to improve the novel Spectral Domain Interferometry method denoted as Master/Slave (MS) Interferometry. In this model, two functions, g and h are introduced to describe the modulation chirp of the channeled spectrum signal due to nonlinearities in the decoding process from wavenumber to time and due to dispersion in the interferometer. The utilization of these two functions brings two major improvements to previous implementations of the MS method. A first improvement consists in reducing the number of channeled spectra necessary to be collected at Master stage. In previous MSI implementation, the number of ...

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    5. Time-domain coherence-gated Shack-Hartmann wavefront sensor

      Time-domain coherence-gated Shack-Hartmann wavefront sensor
      In the present paper we investigate the possibility of narrowing the depth range of a physical Shack - Hartmann wavefront sensor (SH-WFS) by using coherence gating. We have already demonstrated a low coherence interferometry (LCI) set-up, capable of generating similar spots patterns as a conventional SH-WFS and also capable of eliminating stray reflections. Here, we evaluate the accuracy of wavefront measurements using a coherence-gated (CG)/SH-WFS. This is based on a Mach-Zehnder interferometer combined with a SH-WFS, that implements time-domain (TD)-LCI acquisition. The wavefront measurement errors introduced by the non-uniform distribution of the reference power over the photo-detector array were ...
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    6. Line-field spectral domain optical coherence tomography using a 2D camera

      A Line-field Spectral Domain Optical Coherence Tomography method is proposed to enable fast B-Scan imaging. This system was constructed from a combination of a conventional Spectral Domain OCT and a line field imaging system, which directs a line-shaped focus onto a specimen. An array of depth-information-encoded-spectra was collected by a two-dimensinal CCD camera. Numeric frequency resampling was applied to rows collected from the camera, followed by Fourier transformation on each individual spectrum obtained. This lead to B-Scan images generated from a single shot event. The performances of the imaging system are discussed. Images from skin of human fingers in-vivo and ...
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    7. Evaluation of the signal noise ratio enhancement of SS-OCT versus TD-OCT using a full field interferometer

      Comparative evaluation of signal-to-noise ratio (SNR) is presented using a Full-field (FF)-OCT configuration, which is adapted to work in either Swept-Source (SS)-Full-field OCT or Time Domain (TD)-Full-field OCT regime. We implement the two regimes in the same set-up, using the same CCD camera and ... [Proc. SPIE 7168, 71682K (2009)] published Fri Feb 20, 2009.
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    1-7 of 7
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  2. Topics in the News

    1. (5 articles) University of Kent
    2. (2 articles) Johns Hopkins University
    3. (2 articles) National University of Ireland, Galway
    4. (1 articles) Boston University
    5. (1 articles) Optos
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    Time-domain coherence-gated Shack-Hartmann wavefront sensor Feature of the Week 05/08/2016: Complex Master Slave Interferometry Full-field optical coherence tomography apply in sphere measurements Simultaneous visible light optical coherence tomography and near infrared OCT angiography in retinal pathologies: A case study A Baseline Study of Oxygen Saturation in Parafoveal Vessels Using Visible Light Optical Coherence Tomography Comparison of Anterior Segment Measurements with a New Multifunctional Unit and Five Other Devices Efficacy of Notal Vision Home OCT demonstrated by a series of scientific and clinical work Synergy Between morpHOlogical and inflammatoRy Evaluation in Predicting Long-term Coronary Plaque Progression Altered ocular microvasculature in patients with systemic sclerosis and very early disease of systemic sclerosis using optical coherence tomography angiography Assessment of macular findings by OCT angiography in patients without clinical signs of diabetic retinopathy: radiomics features for early screening of diabetic retinopathy Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study The Use of Optical Coherence Tomography to Demonstrate Dark and Light Adaptation in a Live Moth