1. Articles from Zachary N. Kon

    1-5 of 5
    1. Intraoperative detection of intimal lipid in the radial artery predicts degree of postoperative spasm

      Background: The radial artery's (RA) tendency to spasm when used as a bypass graft may relate to features of the RA itself. We imaged RA conduits before and after CABG in order to characterize intimal abnormalities that might relate to the risk of spasm.Methods: RA conduits from thirty-two CABG patients were imaged intraoperatively using catheter-based optical coherence tomography (OCT) and again on day 5 using 64-channel MDCT angiography. The change in luminal diameter between timepoints was measured in the proximal, mid and distal RA. “Spasm” was defined as focal or diffuse luminal narrowing to a diameter less than ...
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    2. Harmonic scalpel versus electrocautery for harvest of radial artery conduits: Reduced risk of spasm and intimal injury on optical coherence tomography

      Objective: Vasospasm is the primary obstacle to widespread adoption of the radial artery as a conduit in coronary artery bypass grafting. We used optical coherence tomography, a catheter-based intravascular imaging modality, to measure the degree of radial artery spasm induced by means of harvest with electrocautery or a harmonic scalpel in patients undergoing coronary artery bypass grafting. Methods: Radial arteries were harvested from 44 consecutive patients with a harmonic scalpel (n = 15) or electrocautery (n = 29). Vessels were imaged before harvesting and after removal from the arm, with saphenous vein tracts serving as internal controls. Optical coherence tomographic findings for ...
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    3. Optical Coherence Tomography Imaging as a Quality Assurance Tool for Evaluating Endoscopic Harvest of the Radial Artery

      Background: Concerns about intimal disruption and spasm have limited enthusiasm for endoscopic radial artery harvest (ERAH), although the risk of these problems after this procedure remains uncertain. Radial artery conduits were screened intraoperatively before and after ERAH vs open harvest using catheter-based high-resolution optical coherence tomography (OCT) imaging. Methods: Twenty-four cadavers and 60 coronary artery bypass graft (CABG) patients scheduled to receive a RA graft underwent OCT imaging before (in situ) and after (ex vivo) open harvest or ERAH. Spasm was quantified by the percentage change in luminal volume between images. Intimal disruption was classified as minor or severe depending ...
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    4. Strategies to reduce intraluminal clot formation in endoscopically harvested saphenous veins

      Strategies to reduce intraluminal clot formation in endoscopically harvested saphenous veins Emile N. Brown, BS^a, Zachary N. Kon, BA^a, Richard Tran, BS^a, Nicholas S. Burris, BS^a, Junyen Gu, MD, PhD^a, Patrick Laird, BA^a, Philip S. Brazio, BS, BA^a, Seeta Kallam, MD^a, Kimberly Schwartz, RNFA, MBA^a, Lisa Bechtel, PA-C^b, Ashish Joshi, MD, MPH^c, Shaosong Zhang, MD, PhD^d, Robert S. Poston, MD^a^, ^a Department of Surgery, Division of Cardiac Surgery, University of Maryland School of Medi
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    5. Thinking inside the graft: applications of optical coherence tomography in coronary artery bypass grafting

      Emile N. Brown, Nicholas S. Burris, Junyan Gu et al. Recent advances in catheter-based optical coherence tomography (OCT) have provided the necessary resolution and acquisition speed for high-quality intravascular imaging. Complications associated with clearing blood from the vessel of a living patient have prevented its wider acceptance. We identify ... [J. Biomed. Opt. 12, 051704 (2007)] published Wed Oct 24, 2007.
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    1-5 of 5
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  2. Topics in the News

    1. (5 articles) University of Maryland
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    Normative data and associations of Optical Coherence Tomography Angiography measurements of the macula: The Singapore Malay Eye Study Automatic Segmentation and Measurement of Choroid Layer in High Myopia for OCT Imaging Using Deep Learning In-process monitoring in laser grooving with line-shaped femtosecond pulses using optical coherence tomography Three-dimensional opto-thermo-mechanical model for predicting photo-thermal optical coherence tomography responses in multilayer geometries The role of optical coherence tomography angiography in moderate and advanced primary open-angle glaucoma OCT-angiography follow-up of choroidal neovascularization treated with treat- and- extend aflibercept regimen to avoid over-treatment A Review of Spectroscopic and Non-Spectroscopic Techniques for Diagnosing Breast Cancer Collaboration Between Seno Medical and Cogmedix Drives GOLDEN Results for Innovative Medical Breast Imaging System Prediction of Retinal Ganglion Cell Counts Considering Various Displacement Methods From OCT-Derived Ganglion Cell-Inner Plexiform Layer Thickness Changes of blood flow in macular zone of patients with diabetic retinopathy at different stages evaluated by optical coherence tomography angiography Very late stent thrombosis lacking findings of the typical causes on optical coherence tomography in a patient with SARS-CoV-2 Coarsening of choriocapillaris on optical coherence tomography angiography as a sign of acute idiopathic blind spot enlargement