1. Articles from Vasudevan Lakshminarayanan

    1-4 of 4
    1. OCTID: Optical Coherence Tomography Image Database

      OCTID: Optical Coherence Tomography Image Database

      Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for the early diagnosis of retinal diseases. In this paper, we describe a comprehensive open-access database containing more than 500 high-resolution images categorized into different pathological conditions. The image classes include Normal (NO), Macular Hole (MH), Age-related Macular Degeneration (AMD), Central Serous Retinopathy, and Diabetic Retinopathy (DR). The images were obtained from a raster scan protocol with a 2mm scan length and 512x1024 pixels resolution. We have also included 25 normal OCT ...

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    2. Classification of optical coherence tomography images for diagnosing different ocular diseases

      Classification of optical coherence tomography images for diagnosing different ocular diseases

      Optical Coherence tomography (OCT) images provide several indicators, e.g., the shape and the thickness of different retinal layers, which can be used for various clinical and non-clinical purposes. We propose an automated classification method to identify different ocular diseases, based on the local binary pattern features. The database consists of normal and diseased human eye SD-OCT images. We use a multiphase approach for building our classifier, including preprocessing, Meta learning, and active learning. Pre-processing is applied to the data to handle missing features from images and replace them with the mean or median of the corresponding feature. All the ...

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    3. Intra-retinal segmentation of optical coherence tomography images using active contours with a dynamic programming initialization and an adaptive weighting strategy

      Intra-retinal segmentation of optical coherence tomography images using active contours with a dynamic programming initialization and an adaptive weighting strategy

      Retinal layer shape and thickness are one of the main indicators in the diagnosis of ocular diseases. We present an active contour approach to localize intra-retinal boundaries of eight retinal layers from OCT images. The initial locations of the active contour curves are determined using a Viterbi dynamic programming method. The main energy function is a Chan-Vese active contour model without edges. A boundary term is added to the energy function using an adaptive weighting method to help curves converge to the retinal layer edges more precisely, after evolving of curves towards boundaries, in final iterations. A wavelet-based denoising method ...

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    4. Reduction of speckle noise from optical coherence tomography images using multi-frame weighted nuclear norm minimization method

      Reduction of speckle noise from optical coherence tomography images using multi-frame weighted nuclear norm minimization method

      In this paper, we propose a speckle noise reduction method for spectral domain optical coherence tomography (SD-OCT) images called multi-frame weighted nuclear norm minimization (MWNNM). This method is a direct extension of weighted nuclear norm minimization (WNNM) in the multi-frame framework since an adequately denoised image could not be achieved with single-frame denoising methods. The MWNNM method exploits multiple B-scans collected from a small area of a SD-OCT volumetric image, and then denoises and averages them together to obtain a high signal-to-noise ratio B-scan. The results show that the image quality metrics obtained by denoising and averaging only five nearby ...

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    1-4 of 4
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    Reduction of speckle noise from optical coherence tomography images using multi-frame weighted nuclear norm minimization method Intra-retinal segmentation of optical coherence tomography images using active contours with a dynamic programming initialization and an adaptive weighting strategy Classification of optical coherence tomography images for diagnosing different ocular diseases OCTID: Optical Coherence Tomography Image Database New OCT-A device allows imaging of nonsedated infants Are nuclei in stratified squamous epithelium high scattering or low scattering? Efficacy of the proximal optimization technique on crossover stenting in coronary bifurcation lesions in the 3D-OCT bifurcation registry COmbined multimodal analysis of Peripheral Retinal and mAcular circulation in Diabetic Retinopathy (COPRA Study) A new step for volumetric laser endomicroscopy: entering the therapeutic realm of endoscopic mucosal resection Depth resolved label-free multimodal optical imaging platform to study morpho-molecular composition of tissue Classification of dry age-related macular degeneration and diabetic macular edema from optical coherence tomography images using dictionary learning Ultra-widefield optical coherence tomographic imaging of posterior vitreous in eyes with high myopia