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Articles from Michael Liebling

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  1. Multiple-cardiac-cycle noise reduction in dynamic optical coherence tomography of the embryonic heart and vasculature

    Explore Article opticsinfobase.org (Nov 20 2009) Cardiology , Developmental Biology

    Multiple-cardiac-cycle noise reduction in dynamic optical coherence tomography of the embryonic heart and vasculature Recent progress in optical coherence tomography (OCT) allows imaging dynamic structures and fluid flow within scattering tissue, such as the beating heart and blood flow in mouse embryos. Accurate representation and analysis of these dynamic behaviors require reducing the noise of the acquired data. Although noise can be reduced by averaging multiple neighboring pixels in space or time, such operations reduce the effective spatial or temporal resolution that can be achieved. We have developed a computational postprocessing technique to restore image sequences of cyclically moving structures that preserves frame rate and spatial resolution. The signal-to-noise ratio (SNR) is improved by ... (Read Full Article)

    Comment on Article Mentions:   Kirill V. Larin   Baylor College of Medicine   University of Houston

  2. Imaging of cardiovascular dynamics in early mouse embryos with swept source optical coherence tomography

    Explore Article SPIE Digital Library (Feb 19 2009) Cardiology

    Congenital cardiovascular defects are very common, occurring in 1% of live births, and cardiovascular failures are the leading cause of birth defect-related deaths in infants. To improve diagnostics, prevention and treatment of cardiovascular abnormalities, we need to understand not only how cells f ... [Proc. SPIE 7168, 71680E (2009)] published Thu Feb 19, 2009. (Read Full Article)

    Comment on Article Mentions:   Baylor College of Medicine   Kirill V. Larin   University of Houston

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