1. Articles from Anne-Fré Swager

    1-4 of 4
    1. Optical coherence tomography in gastroenterology: a review and future outlook

      Optical coherence tomography in gastroenterology: a review and future outlook

      Optical coherence tomography (OCT) is an imaging technique optically analogous to ultrasound that can generate depth-resolved images with micrometer-scale resolution. Advances in fiber optics and miniaturized actuation technologies allow OCT imaging of the human body and further expand OCT utilization in applications including but not limited to cardiology and gastroenterology. This review article provides an overview of current OCT development and its clinical utility in the gastrointestinal tract, including disease detection/differentiation and endoscopic therapy guidance, as well as a discussion of its future applications.

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    2. Computer-aided detection of early Barrett’s neoplasia using volumetric laser endomicroscopy

      Computer-aided detection of early Barrett’s neoplasia using volumetric laser endomicroscopy

      Background and Aims Volumetric laser endomicroscopy (VLE) is an advanced imaging system that provides a near-microscopic resolution scan of the esophageal wall layers up to 3-mm deep. VLE has the potential to improve detection of early neoplasia in Barrett’s esophagus (BE). However, interpretation of VLE images is complex because of the large amount of data that need to be interpreted in real time. The aim of this study was to investigate the feasibility of a computer algorithm to identify early BE neoplasia on ex vivo VLE images. Methods We used 60 VLE images from a database of high-quality ex ...

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    3. Automated segmentation and characterization of esophageal wall in vivo by tethered capsule optical coherence tomography endomicroscopy

      Automated segmentation and characterization of esophageal wall in vivo by tethered capsule optical coherence tomography endomicroscopy

      Optical coherence tomography (OCT) is an optical diagnostic modality that can acquire cross-sectional images of the microscopic structure of the esophagus, including Barrett’s esophagus (BE) and associated dysplasia. We developed a swallowable tethered capsule OCT endomicroscopy (TCE) device that acquires high-resolution images of entire gastrointestinal (GI) tract luminal organs. This device has a potential to become a screening method that identifies patients with an abnormal esophagus that should be further referred for upper endoscopy. Currently, the characterization of the OCT-TCE esophageal wall data set is performed manually, which is time-consuming and inefficient. Additionally, since the capsule optics optimally focus ...

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    4. Detection of buried Barrett’s glands after radiofrequency ablation with volumetric laser endomicroscopy

      Detection of buried Barrett’s glands after radiofrequency ablation with volumetric laser endomicroscopy

      Background and Aims The prevalence and clinical relevance of buried Barrett’s glands (BB) after radiofrequency ablation (RFA) in Barrett’s esophagus (BE) are debated. Recent optical coherence tomography studies demonstrated a high prevalence of BBs. Direct histological correlation, however, has been lacking. Volumetric laser endomicroscopy (VLE) is a second-generation optical coherence tomography system capable of scanning a large surface of the esophageal wall layers with low-power microscopy resolution. The aim was to evaluate whether post-RFA subsquamous glandular structures (SGSs), detected with VLE, actually correspond to BBs by pursuing direct histological correlation with VLE images. Methods In vivo VLE was ...

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    1-4 of 4
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  2. Topics in the News

    1. (2 articles) Academic Medical Center at the University of Amsterdam
    2. (2 articles) Massachusetts General Hospital
    3. (2 articles) Harvard University
    4. (2 articles) Norman S. Nishioka
    5. (2 articles) NinePoint Medical
    6. (1 articles) Guillermo J. Tearney
    7. (1 articles) Daniël M. de Bruin
    8. (1 articles) Dirk J. Faber
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    10. (1 articles) NinePoint Nvision VLE Imaging System
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    Detection of buried Barrett’s glands after radiofrequency ablation with volumetric laser endomicroscopy Automated segmentation and characterization of esophageal wall in vivo by tethered capsule optical coherence tomography endomicroscopy Computer-aided detection of early Barrett’s neoplasia using volumetric laser endomicroscopy Optical coherence tomography in gastroenterology: a review and future outlook Comparative study between intravitreal ranibizumab and triamcinolone treatment of diabetic macular edema as regard to optical coherence tomography changes and visual acuity What’s New in Optical Coherence Tomography Angiography for Glaucoma (Book Chapter) Looking into the Future: Optical Coherence Tomography for the Assessment of Cardiac Allograft Vasculopathy Effects of Age on Peripapillary and Macular Vessel Density Determined Using Optical Coherence Tomography Angiography in Healthy Eyes Deep Neural Network Regression for Automated Retinal Layer Segmentation in Optical Coherence Tomography Images In-Stent Restenosis Lesion Morphology Related to Repeat Stenting Underexpansion as Evaluated by Optical Coherence Tomography Measurement of granule layer thickness in a spouted bed coating process via optical coherence tomography Angiography and optical coherence tomography assessment of the drug-coated balloon ESSENTIAL for the treatment of in-stent restenosis