1. Articles from Xianjin Dai

    1-3 of 3
    1. Miniature multimodal endoscopic probe based on double-clad fiber

      Miniature multimodal endoscopic probe based on double-clad fiber

      Optical coherence tomography (OCT) can obtain light scattering properties with a high resolution, while photoacoustic imaging (PAI) is ideal for mapping optical absorbers in biological tissues, and ultrasound (US) could penetrate deeply into tissues and provide elastically structural information. It is attractive and challenging to integrate these three imaging modalities into a miniature probe, through which, both optical absorption and scattering information of tissues as well as deep-tissue structure can be obtained. Here, we present a novel side-view probe integrating PAI, OCT and US imaging based on double-clad fiber which is used as a common optical path for PAI (light ...

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    2. Miniature Endoscope for Multimodal Imaging

      Miniature Endoscope for Multimodal Imaging

      A single miniature endoscope capable of concurrently probing multiple contrast mechanisms of tissue in high resolution is highly attractive, as it makes it possible for providing complementary, more complete tissue information on internal organs hard to access. Here we describe such a miniature endoscope only 1 mm in diameter that integrates photoacoustic imaging (PAI), optical coherence tomography (OCT), and ultrasound (US). The integration of PAI/OCT/US allows for high-resolution imaging of three tissue contrasts including optical absorption (PAI), optical scattering (OCT), and acoustic properties (US). We demonstrate the capabilities of this trimodal endoscope using mouse ear, human hand, and ...

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    3. Miniature probe integrating optical-resolution photoacoustic microscopy, optical coherence tomography, and ultrasound imaging: proof-of-concept

      Miniature probe integrating optical-resolution photoacoustic microscopy, optical coherence tomography, and ultrasound imaging: proof-of-concept

      In this Letter, we present a novel tri-modal miniature side-view probe, through which optical-resolution photoacoustic microscopy (OR-PAM), optical coherence tomography (OCT), and pulse-echo ultrasound (US) images can be coaxially acquired and displayed simultaneously. The probe consists of a common optical path for OR-PAM (light delivery) and OCT (light delivery/detection), and a 40-MHz unfocused ultrasound transducer for OR-PAM (photoacoustic detection) and US (ultrasound transmission/receiving) with an overall diameter of 2 mm. Combining OR-PAM, OCT, and US would provide complementary information including optical absorption (OR-PAM), optical back-scattering (OCT), and deep tissue structures (US) about biological tissue. Based on an integrated ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) University of Florida
    2. (3 articles) Huikai K. Xie
    3. (2 articles) Harvard University
    4. (2 articles) Massachusetts General Hospital
    5. (2 articles) Carl Zeiss Meditec
    6. (1 articles) Medical University of Vienna
    7. (1 articles) University of Hong Kong
    8. (1 articles) Guillermo J. Tearney
    9. (1 articles) Desmond C. Adler
    10. (1 articles) Matthew J. Everett
    11. (1 articles) Nathan D. Shemonski
    12. (1 articles) Ursula Schmidt-Erfurth
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