1. Articles from Carolina P. B. Gracitelli

    1-6 of 6
    1. Macular Inner Retinal Layer Thinning in Diabetic Patients without Retinopathy Measured by Spectral Domain Optical Coherence Tomography

      Macular Inner Retinal Layer Thinning in Diabetic Patients without Retinopathy Measured by Spectral Domain Optical Coherence Tomography

      The aim of this study was to use Spectral Domain-Optical Coherence Tomography (SD-OCT) to measure the thickness of the Macular Inner Retinal Layer (MIRL) and compare the results between diabetic patients with no signs of retinopathy and healthy subjects. Overall, 47 type 2 diabetic patients without clinical signs of retinopathy were prospectively analyzed along with 36 healthy subjects. This study excluded patients with other systemic or ocular diseases. All patients had their MIRL thickness measured by RTVue-100 SD-OCT (7x7 mm macular grid). The MIRL thickness is provided by the ganglion cell complex scan (comprised of the retinal nerve fiber, ganglion ...

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    2. Association between Intraocular Pressure and Rates of Retinal Nerve Fiber Layer Loss Measured by Optical Coherence Tomography

      Association between Intraocular Pressure and Rates of Retinal Nerve Fiber Layer Loss Measured by Optical Coherence Tomography

      Purpose To evaluate the relationship between intraocular pressure (IOP) and rates of retinal nerve fiber layer (RNFL) thickness change over time measured by spectral-domain (SD) optical coherence tomography (OCT). Design Observational cohort study. Participants The study involved 547 eyes of 339 patients followed up for an average of 3.9±0.9 years. Three hundred eight (56.3%) had a diagnosis of glaucoma and 239 (43.7%) were considered glaucoma suspects. Methods All eyes underwent imaging using the Spectralis SD OCT (Heidelberg Engineering GmbH, Heidelberg, Germany), along with IOP measurements and standard automated perimetry (SAP). Glaucoma progression was defined as ...

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    3. The Relative Odds of Progressing by Structural and Functional Tests in Glaucoma

      The Relative Odds of Progressing by Structural and Functional Tests in Glaucoma

      Purpose : The purpose of this study was to evaluate the effect of disease severity and number of tests acquired during follow-up on the relative odds of identifying progression by structural or functional tests in glaucoma. Methods : This was an observational cohort study involving 462 eyes of 305 patients with glaucoma and 62 eyes of 49 healthy subjects. Glaucoma patients and healthy subjects were followed for an average of 3.6 ± 0.9 and 3.8 ± 0.9 years, with a median (interquantile range) of 8 (6–9) and 7 (6–8) visits, respectively. At each visit, subjects underwent visual field ...

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    4. Identification of the Most Accurate Spectral-domain Optical Coherence Tomography Parameters in Eyes With Early High-Tension and Low-Tension Glaucoma

      Identification of the Most Accurate Spectral-domain Optical Coherence Tomography Parameters in Eyes With Early High-Tension and Low-Tension Glaucoma

      Purpose: The aim of the study was to compare the diagnostic ability of macular ganglion cell complex (GCC) and peripapillary retinal nerve fiber layer (pRNFL) thickness in high-tension glaucoma (HTG) and low-tension glaucoma (LTG). Patients and Methods: Glaucoma was defined as glaucomatous optic neuropathy and reproducible visual field defects. Patients were classified as having LTG if untreated intraocular pressure was <=21 mm Hg on 2 different occasions. Only eyes with early glaucoma (mean deviation <-6 dB) were included. All patients underwent spectral-domain optical coherence tomography (SDOCT) imaging. Results: A total of 56 normal subjects, 64 HTG patients, and 35 LTG ...

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    5. The Use of Spectral-Domain Optical Coherence Tomography to Detect Glaucoma Progression

      The Use of Spectral-Domain Optical Coherence Tomography to Detect Glaucoma Progression

      Detection of progression and measurement of rates of change is at the core of glaucoma management, and the use of Spectral Domain Optical Coherence Tomography (SD-OCT) has significantly improved our ability to evaluate change in the disease. In this review, we critically assess the existing literature on the use of SD-OCT for detecting glaucoma progression and estimating rates of change. We discuss aspects related to the reproducibility of measurements, their accuracy to detect longitudinal change over time, and the effect of aging on the ability to detect progression. In addition, we discuss recent studies evaluating the use of combined structure ...

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    6. Spectral-Domain Optical Coherence Tomography for Glaucoma Diagnosis

      Spectral-Domain Optical Coherence Tomography for Glaucoma Diagnosis

      Identification of structural damage to the optic nerve and retinal nerve fiber layer (RNFL) is an essential component of diagnosis and management of glaucoma. The introduction of spectral-domain OCT (SD-OCT) has allowed objective quantification of damage to these structures with unprecedented resolution. In addition, recent attention has been directed towards imaging the macular area for quantifying loss of neural tissue caused by the disease. Many studies have evaluated and compared the diagnostic accuracies of a variety of parameters that can be obtained from imaging these areas of the ocular fundus. In this article, we critically review the existing literature evaluating ...

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    1-6 of 6
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  2. Topics in the News

    1. (4 articles) Felipe A. Medeiros
    2. (3 articles) Universidade Federal de São Paulo
    3. (3 articles) UCSD
    4. (2 articles) Linda M. Zangwill
    5. (2 articles) Robert N. Weinreb
    6. (1 articles) UC Davis
    7. (1 articles) Christopher A. Girkin
    8. (1 articles) Jeffrey M. Liebmann
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    Spectral-Domain Optical Coherence Tomography for Glaucoma Diagnosis The Use of Spectral-Domain Optical Coherence Tomography to Detect Glaucoma Progression Identification of the Most Accurate Spectral-domain Optical Coherence Tomography Parameters in Eyes With Early High-Tension and Low-Tension Glaucoma The Relative Odds of Progressing by Structural and Functional Tests in Glaucoma Association between Intraocular Pressure and Rates of Retinal Nerve Fiber Layer Loss Measured by Optical Coherence Tomography Macular Inner Retinal Layer Thinning in Diabetic Patients without Retinopathy Measured by Spectral Domain Optical Coherence Tomography KU Leuven leads €6 million research project on heart disease and dementia Gabor optical coherence tomographic angiography (GOCTA) (Part II): theoretical basis of sensitivity improvement and optimization for processing speed Retinal Neovascularization–Simulating Retinal Capillary Reperfusion in Branch Retinal Vein Occlusion, Imaged by Wide-Field Optical Coherence Tomography Angiography Conjunctival and Episcleral Blood Flow Restoration After Strabismus Surgery on Swept-Source Optical Coherence Tomography Angiography A Framework for Multiscale Quantitation of Relationships Between Choriocapillaris Flow Impairment and Geographic Atrophy Growth Special Section Guest Editorial: Advances in Retinal Imaging