1. Articles from Kristina IRSCH

    1-5 of 5
    1. Method and system for improving aiming during optical coherence tomography on young children by synchronization with retinal bifringence scanning

      Method and system for improving aiming during optical coherence tomography on young children by synchronization with retinal bifringence scanning

      The present invention is directed to a method and system for improved aiming during Optical Coherence Tomography (OCT) on young children and those unable to cooperate with OCT imaging by synchronization with retinal birefringence scanning (RBS). OCT is performed without knowing whether or not the subject is looking at the intended target. The present invention combines OCT retinal imaging, such as, but not limited to, time domain OCT, SDOCT, or SSOCT, with RBS technology that provides accurate information on the presence or absence of foveal fixation. Therefore, the present invention only analyzes data during foveal fixation. A system combining OCT ...

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    2. In vivo imaging through the entire thickness of human cornea by full-field optical coherence tomography

      In vivo imaging through the entire thickness of human cornea by full-field optical coherence tomography

      Despite obvious improvements in visualization of the in vivo cornea through the faster imaging speeds and higher axial resolutions, cellular imaging stays unresolvable task for OCT, as en face viewing with a high lateral resolution is required. The latter is possible with FFOCT, a method that relies on a camera, moderate numerical aperture (NA) objectives and an incoherent light source to provide en face images with a micrometer-level resolution. Recently, we for the first time demonstrated the ability of FFOCT to capture images from the in vivo human cornea1. In the current paper we present an extensive study of appearance ...

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    3. Motion-compensated optical coherence tomography using envelope-based surface detection and Kalman-based prediction

      Motion-compensated optical coherence tomography using envelope-based surface detection and Kalman-based prediction

      We present an optical coherence tomography (OCT) imaging system that effectively compensates unwanted axial motion with micron-scale accuracy. The OCT system is based on a swept-source (SS) engine (1060-nm center wavelength, 100-nm full-width sweeping bandwidth, and 100-kHz repetition rate), with axial and lateral resolutions of about 4.5 and 8.5 microns respectively. The SS-OCT system incorporates a distance sensing method utilizing an envelope-based surface detection algorithm. The algorithm locates the target surface from the B-scans, taking into account not just the first or highest peak but the entire signature of sequential A-scans. Subsequently, a Kalman filter is applied as ...

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    4. In vivo high resolution human corneal imaging using full-field optical coherence tomography

      In vivo high resolution human corneal imaging using full-field optical coherence tomography

      We present the first full-field optical coherence tomography (FFOCT) device capable of in vivo imaging of the human cornea. We obtained images of the epithelial structures, Bowman’s layer, sub-basal nerve plexus (SNP), anterior and posterior stromal keratocytes, stromal nerves, Descemet’s membrane and endothelial cells with visible nuclei. Images were acquired with a high lateral resolution of 1.7 µm and relatively large field-of-view of 1.26 mm x 1.26 mm – a combination, which, to the best of our knowledge, has not been possible with other in vivo human eye imaging methods. The latter together with a contactless ...

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    5. Method And System For Improving Aiming During Optical Coherence Tomography On Young Children By Synchronization With Retinal Bifringence Scanning

      Method And System For Improving Aiming During Optical Coherence Tomography On Young Children By Synchronization With Retinal Bifringence Scanning

      The present invention is directed to a method and system for improved aiming during Optical Coherence Tomography (OCT) on young children and those unable to cooperate with OCT imaging by synchronization with retinal birefringence scanning (RBS). OCT is performed without knowing whether or not the subject is looking at the intended target.

      Read Full Article
    1-5 of 5
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    1. (3 articles) Johns Hopkins University
    2. (2 articles) ESPCI ParisTech
    3. (2 articles) Duke University
    4. (2 articles) Mathias Fink
    5. (2 articles) Claude Boccara
    6. (2 articles) Cynthia A. Toth
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    Method And System For Improving Aiming During Optical Coherence Tomography On Young Children By Synchronization With Retinal Bifringence Scanning In vivo high resolution human corneal imaging using full-field optical coherence tomography Motion-compensated optical coherence tomography using envelope-based surface detection and Kalman-based prediction In vivo imaging through the entire thickness of human cornea by full-field optical coherence tomography Method and system for improving aiming during optical coherence tomography on young children by synchronization with retinal bifringence scanning Postdoctoral Associate Position at Duke Vision and Image Processing Laborator Anterior segment optical coherence tomography angiography Refining percutaneous coronary intervention: intracoronary imaging, haemodynamics, P2Y12 antagonists, and public outcomes reporting Optical Coherence Tomography/Fluorescence Imaging: Fiber assembly enables efficient multimodal endoscopy Optical Fabrication: Glassblowing technique creates arrays of axicon lenses University of Alabama Receives NIH Grant  for Clinical and Translational Core. University of Alabama Receives NIH Grant for Cell Model Evaluation Core.