1. Articles from Elaine M. Wells-Gray

    1-4 of 4
    1. Inner Retinal Changes in Primary Open-Angle Glaucoma Revealed Through Adaptive Optics-Optical Coherence Tomography

      Inner Retinal Changes in Primary Open-Angle Glaucoma Revealed Through Adaptive Optics-Optical Coherence Tomography

      Purpose: To examine the microstructural changes in the inner nuclear layer (INL) and ganglion cell layer (GCL) in a primary open-angle glaucoma (POAG) subject at 2 timepoints, 4 months apart. Patients and Methods: This case-control study (1 POAG subject and 1 normal control) used the single cell, 3-dimensional volumetric imaging capability of an adaptive optics - optical coherence tomography -scanning laser ophthalmoscopy system to examine the inner retina. Results: At the area of greatest glaucomatous change in the POAG subject [3-degrees temporal (T), 3-degrees inferior (I), right eye], the GCL was greatly thinned at both timepoints, yet retinal ganglion cell soma ...

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    2. Inner Retinal Changes in Primary Open Angle Glaucoma Revealed through Adaptive Optics Optical Coherence Tomography

      Inner Retinal Changes in Primary Open Angle Glaucoma Revealed through Adaptive Optics Optical Coherence Tomography

      Purpose: To examine the microstructural changes in the inner nuclear layer (INL) and ganglion cell layer (GCL) in a primary open angle glaucoma (POAG) patient at 2 time points, 4 months apart. Patients and Methods: This case-control study (one POAG patient and one normal control) used the single cell, three-dimensional volumetric imaging capability of an adaptive optics - optical coherence tomography -scanning laser ophthalmoscopy system to examine the inner retina. Results: At the area of greatest glaucomatous change in the POAG patient (3°T-3°I, right eye), the GCL was greatly thinned at both time points, yet retinal ganglion cell (RGC ...

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    3. Volumetric imaging of rod and cone photoreceptor structure with a combined adaptive optics-optical coherence tomography-scanning laser ophthalmoscope

      Volumetric imaging of rod and cone photoreceptor structure with a combined adaptive optics-optical coherence tomography-scanning laser ophthalmoscope

      We have designed and implemented a dual-mode adaptive optics (AO) imaging system that combines spectral domain optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO) for in vivo imaging of the human retina. The system simultaneously acquires SLO frames and OCT B-scans at 60 Hz with an OCT volume acquisition time of 4.2 s. Transverse eye motion measured from the SLO is used to register the OCT B-scans to generate three-dimensional (3-D) volumes. Key optical design considerations include: minimizing system aberrations through the use of off-axis relay telescopes, conjugate pupil plane requirements, and the use of dichroic beam splitters ...

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    4. Performance of a combined optical coherence tomography and scanning laser ophthalmoscope with adaptive optics for human retinal imaging application

      Performance of a combined optical coherence tomography and scanning laser ophthalmoscope with adaptive optics for human retinal imaging application

      We describe the design and performance of a recently implemented retinal imaging system for the human eye that combines adaptive optics (AO) with spectral domain optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO). The AO-OCT-SLO system simultaneously acquires SLO frames and OCT B-scans at 60 Hz with an OCT volume acquisition scan rate of 0.24 Hz. The SLO images are used to correct for eye motion during the registration of OCT B-scans. Key optical design considerations are discussed including: minimizing system aberrations through the use of off-axis relay telescopes; choice of telescope magnification based on pupil plane requirements ...

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    1-4 of 4
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    1. (3 articles) The Ohio State University
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    Performance of a combined optical coherence tomography and scanning laser ophthalmoscope with adaptive optics for human retinal imaging application Volumetric imaging of rod and cone photoreceptor structure with a combined adaptive optics-optical coherence tomography-scanning laser ophthalmoscope Inner Retinal Changes in Primary Open Angle Glaucoma Revealed through Adaptive Optics Optical Coherence Tomography Inner Retinal Changes in Primary Open-Angle Glaucoma Revealed Through Adaptive Optics-Optical Coherence Tomography Postdoctoral Fellows/Research Scientists at University of Washington, Seattle Perimeter Medical Imaging AI Announces Publication of Peer-Reviewed Journal Article Validating Potential Use of Wide-Field Optical Coherence Tomography (WF-OCT) in Head and Neck Surgeries Association of retinal thickness and microvasculature with cognitive performance and brain volumes in elderly adults A Deep Learning Framework for the Detection and Quantification of Reticular Pseudodrusen and Drusen on Optical Coherence Tomography Quantitative assessment of textural features in the early detection of diabetic retinopathy with optical coherence tomography angiography Line-field confocal optical coherence tomography of fibroepithelioma of Pinkus Assessment of demineralized tooth lesions using optical coherence tomography and other state-of-the-art technologies: a review Optic disc and retinal vessel densities assessment by optical coherence tomography angiography in patients with keratoconus