1. Articles from Won Hyuk Jang

    1-5 of 5
    1. Characterization of early-stage cutaneous radiation injury by using optical coherence tomography angiography

      Characterization of early-stage cutaneous radiation injury by using optical coherence tomography angiography

      Cutaneous radiation injury (CRI) is a skin injury caused by exposure to high dose ionizing radiation (IR). Diagnosis and treatment of CRI is difficult due to its initial clinically latent period and the following inflammatory bursts. Early detection of CRI before clinical symptoms will be helpful for effective treatment, and various optical methods have been applied with limitations. Here we show that optical coherence tomography angiography (OCTA) could detect changes in the skin during the latent period in CRI mouse models non-invasively. CRI was induced on the mouse hindlimb with exposure to various IR doses and the injured skin regions ...

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      Mentions: Ki Hean Kim
    2. Dermoscopy guided dark-field multi-functional optical coherence tomography

      Dermoscopy guided dark-field multi-functional optical coherence tomography

      Dermoscopy is a skin surface microscopic technique allowing specular reflection free observation of the skin, and has been used to examine pigmented skin lesions. However, dermoscopy has limitations in providing depth information due to lack of 3D resolution. In order to overcome the limitations, we developed dermoscopy guided multi-functional optical coherence tomography (MF-OCT) providing both high-contrast superficial information and depth-resolved structural, birefringent, and vascular information of the skin simultaneously. Dermoscopy and MF-OCT were combined by using a dichroic mirror, and dark-field configuration was adapted for MF-OCT to reduce specular reflection. After characterization, dermoscopy guided MF-OCT was applied to several human ...

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    3. Visualization of prostatic nerves by polarization-sensitive optical coherence tomography

      Visualization of prostatic nerves by polarization-sensitive optical coherence tomography

      Preservation of prostatic nerves is critical to recovery of a man’s sexual potency after radical prostatectomy. A real-time imaging method of prostatic nerves will be helpful for nerve-sparing radical prostatectomy (NSRP). Polarization-sensitive optical coherence tomography (PS-OCT), which provides both structural and birefringent information of tissue, was applied for detection of prostatic nerves in both rat and human prostate specimens, ex vivo. PS-OCT imaging of rat prostate specimens visualized highly scattering and birefringent fibrous structures superficially, and these birefringent structures were confirmed to be nerves by histology or multiphoton microscopy (MPM). PS-OCT could easily distinguish these birefringent structures from surrounding ...

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      Mentions: Ki Hean Kim
    4. Dark-field polarization-sensitive optical coherence tomography

      Dark-field polarization-sensitive optical coherence tomography

      Polarization-sensitive optical coherence tomography (PS-OCT) is a functional OCT providing both structural and birefringent information of the sample, and it has been applied to the studies of various organs having polarization properties. Fiber-based PS-OCT is sensitive to specular reflection from the sample surface, because signal saturation due to the strong specular reflection can make the polarization measurement difficult. We developed a dark-field PS-OCT which can avoid the specular reflection problem. Dark-field PS-OCT was implemented by adapting a hybrid method of Bessel-beam illumination and Gaussian-beam detection, and a PS-OCT method based on passive delay unit (PDU). The new system was characterized ...

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    5. In vivo wide-field reflectance/fluorescence imaging and polarization-sensitive optical coherence tomography of human oral cavity with a forward-viewing probe

      In vivo wide-field reflectance/fluorescence imaging and polarization-sensitive optical coherence tomography of human oral cavity with a forward-viewing probe

      We report multimodal imaging of human oral cavity in vivo based on simultaneous wide-field reflectance/fluorescence imaging and polarization-sensitive optical coherence tomography (PS-OCT) with a forward-viewing imaging probe. Wide-field reflectance/fluorescence imaging and PS-OCT were to provide both morphological and fluorescence information on the surface, and structural and birefringent information below the surface respectively. The forward-viewing probe was designed to access the oral cavity through the mouth with dimensions of approximately 10 mm in diameter and 180 mm in length. The probe had field of view (FOV) of approximately 5.5 mm in diameter, and adjustable depth of field (DOF ...

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    1-5 of 5
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  2. Topics in the News

    1. (5 articles) Ki Hean Kim
    2. (2 articles) Yonsei University
    3. (2 articles) Taejun Wang
    4. (1 articles) Gwangju Institute of Science and Technology
    5. (1 articles) Chulmin Joo
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    In vivo wide-field reflectance/fluorescence imaging and polarization-sensitive optical coherence tomography of human oral cavity with a forward-viewing probe Dark-field polarization-sensitive optical coherence tomography Visualization of prostatic nerves by polarization-sensitive optical coherence tomography Dermoscopy guided dark-field multi-functional optical coherence tomography Characterization of early-stage cutaneous radiation injury by using optical coherence tomography angiography Heterogeneity of Neointimal Healing Following Biodegradable-polymer Drug-Eluting Coronary Stent Implantation Swept-source and multimodal OCT technologies offer clinical advantages Early vascular response of ultra-thin bioresorbable polymer sirolimus-eluting stents assessed by optical frequency domain imaging: the EVALUATION study OCT, OCTA show promise in screening for DR Improved Diagnostic Imaging of Brain Tumors by Multimodal Microscopy and Deep Learning Thromboembolic or atherosclerotic? Optical coherence tomography in determining the cause of myocardial infarction with ST-segment elevation Application of Artificial Intelligence in Targeting Retinal Diseases