1. Articles from Manuel G. Penedo

    1-8 of 8
    1. Intraretinal fluid map generation in optical coherence tomography images (book chapter)

      Intraretinal fluid map generation in optical coherence tomography images (book chapter)

      The retina represents one of the most studied parts of the human body, thanks to its easy access for any ophthalmological study. It represents the main neurosensory part of the eye and, by its study, pathologies not only from the visual system but also from different body systems (like the neural system or vascular system) can be detected. Among the principal medical imaging modalities that are used to study the eye fundus and the retinal histological structures, the optical coherence tomography (OCT) has proven to be one of the most reliable techniques. It is widely used for the detection of ...

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    2. Intuitive and Coherent Intraretinal Cystoid Map Representation in Optical Coherence Tomography Images

      Intuitive and Coherent Intraretinal Cystoid Map Representation in Optical Coherence Tomography Images

      Fluid accumulations in between the retinal layers represent one of the main causes of blindness in developed countries. Currently, these fluid accumulations are detected by means of a manual inspection of Optical Coherence Tomography images, prone to subjective and non-quantifiable diagnostics. For this reason, numerous works aimed for an automated methodology. Nonetheless, these systems mostly focus on obtaining a defined segmentation, which is not always possible. For this reason, we present in this work a fully automatic methodology based in a fuzzy and confidence-based visualization of a regional analysis, allowing the clinicians to study the fluid accumulations independently of their ...

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    3. Intraretinal Fluid Pattern Characterization in Optical Coherence Tomography Images

      Intraretinal Fluid Pattern Characterization in Optical Coherence Tomography Images

      Optical Coherence Tomography (OCT) has become a relevant image modality in the ophthalmological clinical practice, as it offers a detailed representation of the eye fundus. This medical imaging modality is currently one of the main means of identification and characterization of intraretinal cystoid regions, a crucial task in the diagnosis of exudative macular disease or macular edema, among the main causes of blindness in developed countries. This work presents an exhaustive analysis of intensity and texture-based descriptors for its identification and classification, using a complete set of 510 texture features, three state-of-the-art feature selection strategies, and seven representative classifier strategies ...

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    4. A Novel Automatic Method to Estimate Visual Acuity and Analyze the Retinal Vasculature in Retinal Vein Occlusion Using Swept Source Optical Coherence Tomography Angiography

      A Novel Automatic Method to Estimate Visual Acuity and Analyze the Retinal Vasculature in Retinal Vein Occlusion Using Swept Source Optical Coherence Tomography Angiography

      The assessment of vascular biomarkers and their correlation with visual acuity is one of the most important issues in the diagnosis and follow-up of retinal vein occlusions (RVOs). The high workloads of clinical practice make it necessary to have a fast, objective, and automatic method to analyze image features and correlate them with visual function. The aim of this study is to propose a fully automatic system which is capable of estimating visual acuity (VA) in RVO eyes, based only on information obtained from macular optical coherence tomography angiography (OCTA) images. We also propose an automatic methodology to rapidly measure ...

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    5. Intraretinal fluid identification via enhanced maps using optical coherence tomography images

      Intraretinal fluid identification via enhanced maps using optical coherence tomography images

      Nowadays, among the main causes of blindness in developed countries are age-related macular degeneration (AMD) and the diabetic macular edema (DME). Both diseases present, as a common symptom, the appearance of cystoid fluid regions inside the retinal layers. Optical coherence tomography (OCT) image modality was one of the main medical imaging techniques for the early diagnosis and monitoring of AMD and DME via this intraretinal fluid detection and characterization. We present a novel methodology to identify these fluid accumulations by means of generating binary maps (offering a direct representation of these areas) and heat maps (containing the region confidence). To ...

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    6. Automatic vessel detection by means of brightness profile characterization in OCT images

      Automatic vessel detection by means of brightness profile characterization in OCT images

      Optical Coherence Tomography (OCT) is a well-established medical imaging technique that allows the analysis of the eye fundus characteristics in real time. These images enable the experts to make a clinical evaluation of the retinal vasculature, whose morphology provides relevant information for diseases like diabetes, hypertension or arteriosclerosis. In this paper, we present a novel proposal for the automatic vasculature identification in retinal OCT images. To achieve this, we analyse the intensity profiles between representative retinal layers, previously segmented. Then, two statistical models are generated using representative samples of vessel and non-vessel profiles. The analysis of both statistical models let ...

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    7. Automatic Identification of Intraretinal Cystoid Regions in Optical Coherence Tomography

      Automatic Identification of Intraretinal Cystoid Regions in Optical Coherence Tomography

      Optical Coherence Tomography (OCT) is, nowadays, one of the most referred ophthalmological imaging techniques. OCT imaging offers a window to the eye fundus in a non-invasive way, permitting the inspection of the retinal layers in a cross sectional visualization. For that reason, OCT images are frequently used in the analysis of relevant diseases such as hypertension or diabetes. Among other pathological structures, a correct identification of cystoid regions is a crucial task to achieve an adequate clinical analysis and characterization, as in the case of the analysis of the exudative macular disease. This paper proposes a new methodology for the ...

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    8. Automatic Vessel Shade-Robust Segmentation of Retinal Layers in OCT Images

      Automatic Vessel Shade-Robust Segmentation of Retinal Layers in OCT Images

      Optical Coherence Tomography (OCT) is a promising imaging technique used by ophthalmologists to diagnose diseases. Since retinal morphology can be identified on these images, several image processing-based methods are emerging with the purpose of extracting their information. The first step to tackle any automatic method to extract pathological features from these images is delimiting retinal layers automatically. This is the aim of this paper, which presents an active contour-based method to segment layer boundaries in the retina. Results obtained by this method present high accuracy and robustness, even when some of these layers are low defined or vessel shades are ...

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    1-8 of 8
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    1. (1 articles) Technical University of Denmark (DTU)
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    Automatic Vessel Shade-Robust Segmentation of Retinal Layers in OCT Images Automatic Identification of Intraretinal Cystoid Regions in Optical Coherence Tomography Automatic vessel detection by means of brightness profile characterization in OCT images Intraretinal fluid identification via enhanced maps using optical coherence tomography images A Novel Automatic Method to Estimate Visual Acuity and Analyze the Retinal Vasculature in Retinal Vein Occlusion Using Swept Source Optical Coherence Tomography Angiography Intraretinal Fluid Pattern Characterization in Optical Coherence Tomography Images Intuitive and Coherent Intraretinal Cystoid Map Representation in Optical Coherence Tomography Images Intraretinal fluid map generation in optical coherence tomography images (book chapter) A case report of a coronary myocardial bridge with impaired full-cycle ratio during dobutamine challenge Diagnosis of chronic stage of hypertensive retinopathy based on spectral domain optical coherence tomography A Cross-sectional Optical Coherence Tomography Study in Patients on Taxane-based Therapy and A Case Report with the Literature Review Determination of peripapillary vessel density in optic disc drusen using EDI-OCT and OCT angiography