1. Featured Articles

    1-13 of 13
    1. Opening for Technology Director – Core Products at Volk Optical Inc.

      Opening for Technology Director – Core Products at Volk Optical Inc.

      Position Summary The Technology Director role presents an exciting opportunity to lead and mentor a highly talented, dynamic and motivated team of engineers working on sustaining, enhancing and developing of currently marketed and new core products including diagnostic, laser and surgical lenses, surgical systems and marketed diagnostic imaging devices. The Product Development team at Volk embraces a culture of collaborative teamwork, impactful & customer-centric innovation, free exchange of ideas, fast-paced development, entrepreneurial mindset and can-do attitude. The ideal candidate will be a hands-on leader with a strong technical background and track record of developing new medical device products. The Director will ...

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      Mentions: Utkarsh Sharma
    2. Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane

      Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane

      An endoscopic optical coherence tomography (OCT) system with a wide field-of-view of 8 mm is presented, which combines the image capability of endoscopic imaging at the middle ear with the advantages of functional OCT imaging, allowing a morphological and functional assessment of the human tympanic membrane. The endoscopic tube has a diameter of 3.5 mm and contains gradient-index optics for simultaneous forward-viewing OCT and video endoscopy. The endoscope allows the three-dimensional visualization of nearly the entire tympanic membrane. In addition, the oscillation of the tympanic membrane is measured spatially resolved and in the frequency range between 500 Hz and ...

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    3. Notal Vision Announces FDA Grants Breakthrough Device Designation for Pioneering Patient-Operated Home Optical Coherence Tomography (OCT) System

      Notal Vision Announces FDA Grants Breakthrough Device Designation for Pioneering Patient-Operated Home Optical Coherence Tomography (OCT) System

      Notal Vision, Ltd., ("Notal") a privately-held ophthalmic diagnostic services company, focused on advancing eye care by extending ophthalmic disease management from the clinic to the home, has announced the U.S. Food and Drug Administration (FDA) granted the Notal Vision Home-based Optical Coherence Tomography (OCT) System with "Breakthrough Device" designation for the agreed upon indications for use. This designation indicates that FDA intends to provide interactive and timely communication with the sponsor during device development and throughout the review process for various types of premarket submissions. FDA's Breakthrough Devices Program was established in late 2016 to help patients gain ...

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      Mentions: FDA Notal Vision
    4. Michelson Diagnostics: Imaging Reveals Changes in Blood Vessel Growth in Deadly Melanoma Skin Cance

      Michelson Diagnostics: Imaging Reveals Changes in Blood Vessel Growth in Deadly Melanoma Skin Cance

      A new clinical study has shown that Dynamic Optical Coherence Tomography imaging of melanomas (D-OCT) reveals changes to the blood vessels that correlate with the depth of invasion of the melanoma. Researchers believe this could lead to a new faster method of rapidly assessing how dangerous a given melanoma is. A more rapid assessment of the risk would potentially allow patients with more serious invasive disease access to the right treatment more directly, doing away with delays inherent in the traditional diagnosis. The technique may also lead to reducing the number of patients with less aggressive tumours receiving sentinel lymph ...

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    5. Computer-Aided Analysis of Gland-Like Subsurface Hyposcattering Structures in Barrett’s Esophagus Using Optical Coherence Tomography

      Computer-Aided Analysis of Gland-Like Subsurface Hyposcattering Structures in Barrett’s Esophagus Using Optical Coherence Tomography

      (1) Background: Barrett’s esophagus (BE) is a complication of chronic gastroesophageal reflux disease and is a precursor to esophageal adenocarcinoma. The clinical implication of subsurface glandular structures of Barrett’s esophagus is not well understood. Optical coherence tomography (OCT), also known as volumetric laser endomicroscopy (VLE), can assess subsurface glandular structures, which appear as subsurface hyposcattering structures (SHSs). The aim of this study is to develop a computer-aided algorithm and apply it to investigate the characteristics of SHSs in BE using clinical VLE data; (2) Methods: SHSs were identified with an initial detection followed by machine learning. Comprehensive SHS ...

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    6. Optical coherence tomography for intracranial aneurysms: a new method for assessing the aneurysm structure

      Optical coherence tomography for intracranial aneurysms: a new method for assessing the aneurysm structure

      Background There is a lack of precise methods for predicting the risk of aneurysm rupture. Therefore, prophylactic treatment is used, which leads to unnecessary potential complications. A new modality enabling a more accurate risk assessment is needed. Optical coherence tomography (OCT) is a new-generation imaging technology that has astonishing resolution for vascular imaging. In this study, OCT was used for the evaluation of intracranial aneurysms. Methods In vivo OCT imaging was performed for aneurysms induced in 6 rabbits and in 9 intracranial aneurysm patients. Catheters were cut short to prevent any extra length from damaging aneurysms and tissues. Images of ...

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      Mentions: Fudan University
    7. Optical Coherence Tomography in Urologic Oncology: a Comprehensive Review

      Optical Coherence Tomography in Urologic Oncology: a Comprehensive Review

      Introduction Optical coherence tomography (OCT) is being investigated in urologic oncology for optical diagnosis. This comprehensive review analyzes the current state of development of OCT for bladder, upper urinary tract, kidney, prostate, testis, and penis cancer. Also, the potential role of OCT with regard to the current diagnostic pathways is critically appraised to guide future developments. Methods Embase and Pubmed were systematically searched for English and German articles on OCT in humans up to December 2017. Reviews were excluded. Case reports were excluded, unless they presented a landmark in the development of OCT. Results Out of 878 articles, 17 relevant ...

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    8. Postdoctoral Research Fellowships (Optical Coherence Tomography) The Tearney Lab at the Wellman Center for Photomedicine

      Postdoctoral Research Fellowships (Optical Coherence Tomography) The Tearney Lab at the Wellman Center for Photomedicine

      A Postdoctoral research fellowship in the area of optical coherence tomography (OCT) is available in the Tearney Lab at the Massachusetts General Hospital (MGH) in the Wellman Center for Photomedicine. This appointment will be made at the rank of postdoctoral fellow or instructor at Harvard Medical School, commensurate with the applicant’s experience. MGH’s role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for developing and translating new OCT technologies with applications in basic and clinical research. The fellowship will focus on high resolution OCT imaging ...

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    9. Clinical feasibility of optical coherence micro-elastography for imaging tumor margins in breast-conserving surgery

      Clinical feasibility of optical coherence micro-elastography for imaging tumor margins in breast-conserving surgery

      It has been demonstrated that optical coherence micro-elastography (OCME) provides additional contrast of tumor compared to optical coherence tomography (OCT) alone. Previous studies, however, have predominantly been performed on mastectomy specimens. Such specimens typically differ substantially in composition and geometry from the more clinically relevant wide-local excision (WLE) specimens excised during breast-conserving surgery. As a result, it remains unclear if the mechanical contrast observed is maintained in WLE specimens. In this manuscript, we begin to address this issue by performing a feasibility study of OCME on 17 freshly excised, intact WLE specimens. In addition, we present two developments required to ...

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    10. Understanding congenital heart defects to prevent them

      Understanding congenital heart defects to prevent them

      To understand cardiovascular failures, the leading cause of birth defect-related deaths in infants, UH professor of biomedical engineering Kirill Larin is teaming up with Baylor College of Medicine professor of cellular and molecular physiology Irina Larina on a chicken and egg hunt. "When the heart develops, it becomes stiffer as required for ability to contract and pump blood," said Larin. "So the question is - does it become stiff because it's contracting, or is it stiff to begin with because it is genetically predefined?" Surprisingly, very little is known about an embryo's developing heart. "Defining how these mechanical factors ...

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    11. Cardiac OCT: 20 Years from Bench to Erosion

      Cardiac OCT: 20 Years from Bench to Erosion

      A 1 hr lecture on intravascular optical coherence tomography by IV-OCT pioneer Dr. IK-Kyung Jang, MD, PhD. Dr. Jang came to Massachusetts General Hospital in 1987 from Leuven University in Belgium, where he has completed his residency in medicine and fellowship in cardiology. He also successfully defended his doctorate thesis at the same university. After his advanced fellowship in cardiology at MGH, he joined the staff and is currently working as a Physician and an interventional cardiologist in the Cardiology Division. He holds currently an academic title of Professor of Medicine at Harvard Medical School. A recipient of the Partners ...

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    12. Artificial intelligence and deep learning in ophthalmology

      Artificial intelligence and deep learning in ophthalmology

      Artificial intelligence (AI) based on deep learning (DL) has sparked tremendous global interest in recent years. DL has been widely adopted in image recognition, speech recognition and natural language processing, but is only beginning to impact on healthcare. In ophthalmology, DL has been applied to fundus photographs, optical coherence tomography and visual fields, achieving robust classification performance in the detection of diabetic retinopathy and retinopathy of prematurity, the glaucoma-like disc, macular oedema and age-related macular degeneration. DL in ocular imaging may be used in conjunction with telemedicine as a possible solution to screen, diagnose and monitor major eye diseases for ...

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    1-13 of 13
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