1. Featured Articles

    1-15 of 15
    1. Farsiu Wins ARVO Foundation/Pfizer Ophthalmics Carl Camras Translational Research Award

      Farsiu Wins ARVO Foundation/Pfizer Ophthalmics Carl Camras Translational Research Award

      Sina Farsiu , an associate professor at Duke University with appointments in biomedical engineering, ophthalmology, electrical and computer engineering, and computer science, has won the 2017 Association for Research in Vision and Ophthalmology (ARVO) Foundation/Pfizer Ophthalmics Carl Camras Translational Research Award . Reserved for scientists under age 45, the award honors excellence in research and fundamental scientific discoveries, concepts and novel technologies. The discovery that each recipient is nominated for must also have led to, or have promise of leading to, clinical applications. Farsiu will receive the award, which includes a $12,000 honorarium, at the 2017 ARVO Annual Meeting held ...

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    2. Intracoronary optical coherence tomography: Clinical and research applications and intravascular imaging software overview

      Intracoronary optical coherence tomography: Clinical and research applications and intravascular imaging software overview

      By providing valuable information about the coronary artery wall and lumen, intravascular imaging may aid in optimizing interventional procedure results and thereby could improve clinical outcomes following percutaneous coronary intervention (PCI). Intravascular optical coherence tomography (OCT) is a light-based technology with a tissue penetration of approximately 1 to 3 mm and provides near histological resolution. It has emerged as a technological breakthrough in intravascular imaging with multiple clinical and research applications. OCT provides detailed visualization of the vessel following PCI and provides accurate assessment of post-procedural stent performance including detection of edge dissection, stent struts apposition, tissue prolapse, and healing ...

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    3. OCT-based full crystalline lens shape change during accommodation in vivo

      OCT-based full crystalline lens shape change during accommodation in vivo

      The full shape of the accommodating crystalline lens was estimated using custom three-dimensional (3-D) spectral OCT and image processing algorithms. Automatic segmentation and distortion correction were used to construct 3-D models of the lens region visible through the pupil. The lens peripheral region was estimated with a trained and validated parametric model. Nineteen young eyes were measured at 0-6 D accommodative demands in 1.5 D steps. Lens volume, surface area, diameter, and equatorial plane position were automatically quantified. Lens diameter & surface area correlated negatively and equatorial plane position positively with accommodation response. Lens volume remained constant and surface area ...

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    4. In-situ biofouling assessment in spacer filled channels using optical coherence tomography (OCT): 3D biofilm thickness mapping

      In-situ biofouling assessment in spacer filled channels using optical coherence tomography (OCT): 3D biofilm thickness mapping

      Membrane systems for water purification can be seriously hampered by biofouling. The use of optical coherence tomography (OCT) to investigate biofilms in membrane systems has recently increased due to the ability to do the characterization in-situ and non-destructively. The OCT biofilm thickness map is presented for the first time as a tool to assess biofilm spatial distribution on a surface. The map allows the visualization and evaluation of the biofilm formation and growth in membrane filtration systems through the use of a false color scale. The biofilm development was monitored with OCT to evaluate the suitability of the proposed approach ...

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    5. Low-cost hand-held probe for depth-resolved low-coherence interferometry

      Low-cost hand-held probe for depth-resolved low-coherence interferometry

      We report on the development of a low-cost hand-held low-coherence interferometric imaging system based on the principle of linear optical coherence tomography (Linear OCT), a technique which was first proposed in the early 2000s as a simpler alternative to the conventional time-domain and Fourier-domain OCT. A bench-top implementation of the proposed technique is first presented and validated. The axial resolution, SNR, and sensitivity roll-of of the system was estimated to be 5.2 μm and 80 dB, and 3.7 dB over a depth of 0.15 mm, respectively. After validating the bench-top system, two hand-held probe implementations for contact-based ...

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    6. Research Assistant/Associate in Biophotonics and Endoscopic Imaging at Imperial College London

      Research Assistant/Associate in Biophotonics and Endoscopic Imaging at Imperial College London

      Research Assistant/Associate in Biophotonics and Endoscopic Imaging Imperial College London - The Hamlyn Centre for Robotic Surgery in association with Department of Computing, Faculty of Engineering Department of Surgery and Cancer, Faculty of Medicine Location: London Salary: £31,740 to £43,350 per annum Hours: Full Time Contract Type: Contract / Temporary Placed on: 13th January 2017 Closes: 13th February 2017 Job Ref: EN20170007LE Research Assistant salary: £31,740 to £33,370 per annum Research Associate salary: £36,070 to £43,350 per annum Fixed term appointment until 31 st May 2019 Applicants are invited to apply for a new vacancy ...

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    7. High-speed OCT light sources and systems

      High-speed OCT light sources and systems

      Imaging speed is one of the most important parameters that define the performance of optical coherence tomography (OCT) systems. During the last two decades, OCT speed has increased by over three orders of magnitude. New developments in wavelength-swept lasers have repeatedly been crucial for this development. In this review, we discuss the historical evolution and current state of the art of high-speed OCT systems, with focus on wavelength swept light sources and swept source OCT systems.

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    8. Simultaneous imaging of atherosclerotic plaque composition and structure with dual-mode photoacoustic and optical coherence tomography

      Simultaneous imaging of atherosclerotic plaque composition and structure with dual-mode photoacoustic and optical coherence tomography

      The composition of plaque is a major determinant of coronary-related clinical syndromes. By combining photoacoustic tomography (PAT) and optical coherence tomography (OCT), the optical absorption and scattering properties of vascular plaque can be revealed and subsequently used to distinguish the plaque composition and structure. The feasibility and capacity of the dual-mode PAT-OCT technique for resolving vascular plaque was first testified by plaque composition mimicking experiment. PAT obtained lipid information due to optical absorption differences, while owing to scattering differences, OCT achieved imaging of collagen. Furthermore, by combining PAT and OCT, the morphological characteristic and scattering difference of normal and lipid-rich ...

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    9. Two from MIT share National Academy of Engineering Fritz J. and Dolores H. Russ Prize

      Two from MIT share National Academy of Engineering Fritz J. and Dolores H. Russ Prize

      The National Academy of Engineering (NAE) 2017 Fritz J. and Dolores H. Russ Prize was awarded to a team of researchers, including two MIT affiliates, for their work in optical coherence tomography. The award committee noted that the research demonstrated “creative engineering to invent imaging technology essential for preventing blindness and treating vascular and other diseases.” The Russ Prize, established in October of 1999, recognizes an outstanding bioengineering achievement in widespread use that improves the human condition as well as acknowledges insights that help the public better understand and appreciate the contributions of engineers to health, well-being and quality of ...

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    10. Acoustic micro-tapping for non-contact 4D imaging of tissue elasticity

      Acoustic micro-tapping for non-contact 4D imaging of tissue elasticity

      Elastography plays a key role in characterizing soft media such as biological tissue. Although this technology has found widespread use in both clinical diagnostics and basic science research, nearly all methods require direct physical contact with the object of interest and can even be invasive. For a number of applications, such as diagnostic measurements on the anterior segment of the eye, physical contact is not desired and may even be prohibited. Here we present a fundamentally new approach to dynamic elastography using non-contact mechanical stimulation of soft media with precise spatial and temporal shaping. We call it acoustic micro-tapping (A ...

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    11. Medical Imaging Innovator Christine Hendon Wins Presidential Honor

      Medical Imaging Innovator Christine Hendon Wins Presidential Honor

      Christine Hendon , assistant professor of electrical engineering at Columbia Engineering , has won the Presidential Early Career Award (PECASE), the highest honor the U.S. government gives to young scientists and engineers. Hendon, who develops innovative medical imaging instruments for use in surgery and breast cancer detection, is one of 102 researchers from across the nation named by President Obama on January 9. “I congratulate these outstanding scientists and engineers on their impactful work,” President Obama said. “These innovators are working to help keep the United States on the cutting edge, showing that federal investments in science lead to advancements that ...

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    12. Heidelberg Engineering and Gauss Medical Corporation Establish an Ophthalmic Healthcare IT Joint Venture in China

      Heidelberg Engineering and Gauss Medical Corporation Establish an Ophthalmic Healthcare IT Joint Venture in China

      The joint venture company, Gauss Infomed, will offer Picture Archiving and Communication Systems (PACS) and Electronic Medical Record (EMR) software, along with other related product solutions for the ophthalmology healthcare IT market. Gauss Infomed will operate out of Beijing and through a local network of offices to deliver its services across the entire country. “China is a fast-growing market and it is of great importance to our company” “The establishment of this joint venture with Heidelberg Engineering comes at a time of growing demand for advanced ophthalmic IT solutions in China,” said Mr. Liu Xidong, Chairman and CEO of Gauss ...

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    13. The University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development

      The University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development

      The University of Houston Receives a 2017 NIH Grant for $311,241 for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development. The principal investigator is Kirll Larin. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. The overall objective of this study is to develop an optical coherence tomography (OCT) based high- resolution mouse embryonic brain imaging and analysis approach, and to use this method in correlation with molecular analysis to understand the interplay between ethanol (EtOH) and nicotine (NIC) effects on embryonic brain development. Maternal exposures ...

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    14. En face coherence microscopy

      En face coherence microscopy

      En face coherence microscopy or flying spot or full field optical coherence tomography or microscopy (FF-OCT/FF-OCM) belongs to the OCT family because the sectioning ability is mostly linked to the source coherence length. In this article we will focus our attention on the advantages and the drawbacks of the following approaches: en face versus B scan tomography in terms of resolution, coherent versus incoherent illumination and influence of aberrations, and scanning versus full field imaging. We then show some examples to illustrate the diverse applications of en face coherent microscopy and show that endogenous or exogenous contrasts can add ...

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    15. SPIE 2017 awards honor biomedical, photonics achievements and dedication to education including Early Career Achievement Award in OCT To Utkarsh Sharma

      SPIE 2017 awards honor biomedical, photonics achievements and dedication to education including Early Career Achievement Award in OCT To Utkarsh Sharma

      The Awards Committee of SPIE, the international society for optics and photonics , has announced 2017 recipients of prestigious annual awards. Technical accomplishments are recognized by these awards, along with meritorious service to the Society and dedication to education. Early Career Achievement Award – Industry: Utkarsh Sharma , Optovue, Inc., is recognized for his demonstrated leadership and innovation in developing novel ideas to successful clinical translation and commercialization; in particular, the development of first FDA-cleared optical coherence tomography (OCT) angiography and other advanced OCT technologies.

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    1-15 of 15
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