1. Featured Articles

    1-13 of 13
    1. Post-Doctoral and Graduate Student Research Positions at the University of Illinois Urbana-Champaign

      Post-Doctoral and Graduate Student Research Positions at the University of Illinois Urbana-Champaign

      The Biophotonics Imaging Laboratory at the Beckman Institute for Advanced Science and Technology on the campus of the University of Illinois Urbana-Champaign has immediate openings for a post-doctoral research associate and a graduate student in the area of otologic (ear) imaging using optical coherence tomography (OCT). Headed by Prof. Stephen Boppart, the Biophotonics Imaging Laboratory is a dynamic and productive interdisciplinary research and training environment focused on developing novel optical biomedical imaging technologies, translating them into clinical applications, and driving them toward commercialization for improving healthcare. 

      Successful candidates are expected to have a strong experimental research background in OCT hardware ...

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    2. Two Postdoc Openings at the Physical Optics and Biophotonics Group at Institute of Physical Chemistry, Warsaw, Poland

      Two Postdoc Openings at the Physical Optics and Biophotonics Group at Institute of Physical Chemistry, Warsaw, Poland

      This project aims to introduce and experimentally verify the authors' original description of physical processes related to the influence of light with partial spatial coherence on image reconstruction in the presence of optical heterogeneity. The proposed research works will allow for a better understanding of physical and technical limitations for imaging with partially spatially coherent light in systems with phase-sensitive (interferometric or holographic) detection. In this fundamental research program, we would like to solve one of the most basic problems of optics, which is in-vivo microscopic imaging in biological samples. This project aims to broaden our knowledge about the image ...

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    3. Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast

      Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast

      Volumetric imaging of dynamic processes with microscopic resolution holds a huge potential in biomedical research and clinical diagnosis. Using supercontinuum light sources and high numerical aperture (NA) objectives, optical coherence tomography (OCT) achieves microscopic resolution and is well suited for imaging cellular and subcellular structures of biological tissues. Currently, the imaging speed of microscopic OCT (mOCT) is limited by the line-scan rate of the spectrometer camera and ranges from 30 to 250 kHz. This is not fast enough for volumetric imaging of dynamic processes in vivo and limits endoscopic application. Using a novel CMOS camera, we demonstrate fast 3-dimensional OCT ...

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    4. Endomicroscopy of the human cochlea using a micro-optical coherence tomography catheter

      Endomicroscopy of the human cochlea using a micro-optical coherence tomography catheter

      Sensorineural hearing loss (SNHL) is one of the most profound public health concerns of the modern era, affecting 466 million people today, and projected to affect 900 million by the year 2050. Advances in both diagnostics and therapeutics for SNHL have been impeded by the human cochlea's inaccessibility for in vivo imaging, resulting from its extremely small size, convoluted coiled configuration, fragility, and deep encasement in dense bone. Here, we develop and demonstrate the ability of a sub-millimeter-diameter, flexible endoscopic probe interfaced with a micro-optical coherence tomography (μOCT) imaging system to enable micron-scale imaging of the inner ear's ...

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    5. Toth Receives 26th Annual Gertrude D. Pyron Award

      Toth Receives 26th Annual Gertrude D. Pyron Award

      This year, the Retina Research Foundation's Gertrude D. Pyron Award is being presented to Cynthia A. Toth, MD , the Joseph A.C. Wadsworth Professor of Ophthalmology at Duke University School of Medicine and professor in the Department of Biomedical Engineering at Duke University’s Pratt School of Engineering. Dr. Toth is also vice chair of clinical research and director of physician-scientist development for Duke Eye Center. The Pyron Award was created by the Retina Research Foundation of Houston, Texas, to recognize outstanding vision scientists whose work contributes to knowledge about vitreoretinal disease. Its $50,000 cash prize includes a ...

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    6. Head-to-head comparison of quantitative measurements between intravascular imaging systems: An in vitro phantom study

      Head-to-head comparison of quantitative measurements between intravascular imaging systems: An in vitro phantom study

      Introduction The present study aimed to compare the accuracy of quantitative measurements by contemporary intravascular imaging systems including optical frequency domain imaging (OFDI), frequency domain optical coherence tomography (FD-OCT), and 6 intravascular ultrasound (IVUS) systems. Methods We imaged five cylindrical phantom models made from an acrylic resin with known lumen diameters (1.51, 2.03, 3.04, 4.04, and 5.04 mm, respectively) using OFDI (FastView and LUNAWAVE, Terumo), FD-OCT (Dragonfly JP and ILUMIEN OPTIS, Abbott Vascular), and 6 mechanically rotating IVUS systems including a system, two 40-MHz, one 45-MHz, two 60-Mhz and one broad-band frequency IVUS systems. The ...

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    7. High-resolution mid-infrared optical coherence tomography with kHz line rate

      High-resolution mid-infrared optical coherence tomography with kHz line rate

      We report on mid-infrared optical coherence tomography (OCT) at 4 µm based on collinear sum-frequency upconversion and promote the A-scan scan rate to 3 kHz. We demonstrate the increased imaging speed for two spectral realizations, one providing an axial resolution of 8.6 µm, and one providing a record axial resolution of 5.8 µm. Image performance is evaluated by sub-surface micro-mapping of a plastic glove and real-time monitoring of C O 2 CO2 in parallel with OCT imaging.

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    8. MEMS-VCSEL as a tunable light source for OCT imaging of long working distance

      MEMS-VCSEL as a tunable light source for OCT imaging of long working distance

      We present a wavelength tunable vertical-cavity surface-emitting laser (VCSEL) constructed by die-bonding a half-cavity InGaAs laser diode (LD) chip onto a silicon-on-insulator chip with a microelectromechanical system electrostatic diaphragm mirror that functions as a Fabry–Perot interferometer. As a result of the short cavity length, the integrated tunable LD has single-mode lasing characteristics with an extremely large coherence length of 150 m or more. The developed wavelength tunable LD is used to perform swept-source optical coherence tomography with a large scan depth, which is applicable to ophthalmic observation for the diagnosis of pathologic nearsightedness based on the measurement of the ...

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      Mentions: Santec
    9. Munch and optical coherence tomography: unravelling historical and artist applied varnish layers in painting collections

      Munch and optical coherence tomography: unravelling historical and artist applied varnish layers in painting collections

      Effective care of large-scale museum collections requires planning that includes the conservation treatment of specific groups of art works, such as appropriate cleaning strategies. Optical coherence tomography (OCT) has been successfully applied as a non-invasive method for the stratigraphic visualisation of the uppermost transparent and semi-transparent layers in paintings, such as varnishes. Several OCT case study examples have further demonstrated the capabilities of the non-contact interferometric technique to measure the thickness of the various varnish layers, to help monitor cleaning and associated optical changes, and to detect past restorations. OCT was applied for the detection of varnishes to 13 paintings ...

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    10. Polarization Sensitive Optical Coherence Tomography for Bronchoscopic Airway Smooth Muscle Detection in Bronchial Thermoplasty-Treated Patients With Asthma

      Polarization Sensitive Optical Coherence Tomography for Bronchoscopic Airway Smooth Muscle Detection in Bronchial Thermoplasty-Treated Patients With Asthma

      Asthma is a chronic inflammatory disease characterized by airway remodeling (AR), including thickening of airway smooth muscle (ASM) as a key element of this alteration. 1 Patients with severe asthma may benefit from bronchial thermoplasty (BT), an endoscopic treatment that targets structural AR and induces ASM reduction. 2 Assessment of AR is critical to evaluate the impact of BT and might provide a tool for patient selection for BT. Polarization sensitive optical coherence tomography (PS-OCT) imaging has been proposed as a minimally invasive diagnostic method to assess ASM mass as an alternative to focal airway biopsies. Bronchoscopic standard optical coherence ...

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    11. Wasatch Photonics announces the appointment of Neil Anderson as Vice President, Gratings and OCT

      Wasatch Photonics announces the appointment of Neil Anderson as Vice President, Gratings and OCT

      Wasatch Photonics is pleased to announce and welcome Neil Anderson, Ph.D. as the new Vice President of Gratings and OCT. In this role, Neil will be responsible for commercial leadership and growth of the company’s transmission gratings and optical coherence tomography business, working with the teams in Logan, UT, and Morrisville, NC, to develop innovative product solutions matched to current and emerging market needs in laser pulse compression, optical coherence tomography (OCT), astronomy, and photonics. Neil is a well-known and respected figure in the optics and photonics industry and brings 15 years of experience supporting customers with optical ...

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    12. A novel 3D printed hollow microneedle microelectromechanical system for controlled, personalized transdermal drug delivery

      A novel 3D printed hollow microneedle microelectromechanical system for controlled, personalized transdermal drug delivery

      The advancement of drug delivery devices is critical for the individualization of patient treatment and the improvement of healthcare. Here, we introduce the 3DMNMEMS, a novel device that combines 3D printing, microneedles (MNs) and Microelectromechanical Systems (MEMS), allowing versatile and controllable by the user transdermal drug delivery. Hollow MNs were designed and 3D printed using Stereolithography, followed by integrating into a MEMS. By employing advanced imaging techniques, we monitored the distribution of liquid delivered by the device within skin tissue in real time. In vivo testing revealed that the delivery of insulin using the 3DMNMEMS achieved improved glycemic control to ...

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    13. Ophthalmic Systems Architect at Zeiss

      Ophthalmic Systems Architect at Zeiss

      JOB SUMMARY: The Ophthalmic Systems Architect is responsible for driving systems architecture design, trade-off analysis, implementation, and validation across cloud-ready ophthalmic diagnostics products. This role collaborates with various functions within ZEISS to define systems requirements for performance, cost, manufacturability, serviceability, and reliability from hardware through software and user experience. The Ophthalmic Systems Architect works from concept phase through commercial launch to ensure meeting customer needs and exceeding their expectations. Deep passion and experience in developing consumer products from prototyping through productization is crucial for success in this role. ESSENTIAL FUNCTIONS: (Responsibilities that are central to the job and MUST be ...

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    1-13 of 13
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