1. Featured Articles

    1-20 of 20
    1. In vivo measurement of skin surface strain and sub-surface layer deformation induced by natural tissue stretching

      In vivo measurement of skin surface strain and sub-surface layer deformation induced by natural tissue stretching

      Stratum corneum and epidermal layers change in terms of thickness and roughness with gender, age and anatomical site. Knowledge of the mechanical and tribological properties of skin associated with these structural changes are needed to aid in the design of exoskeletons, prostheses, orthotics, body mounted sensors used for kinematics measurements and in optimum use of wearable on-body devices. In this case study, optical coherence tomography (OCT) and digital image correlation (DIC) were combined to determine skin surface strain and sub-surface deformation behaviour of the volar forearm due to natural tissue stretching. The thickness of the epidermis together with geometry changes ...

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    2. Characterization of Automotive Paint by Optical Coherence Tomography

      Characterization of Automotive Paint by Optical Coherence Tomography

      Automotive paint is a common trace evidence that plays a significant role in many vehicle-related criminal cases. However, the conventional methods of obtaining tomographic images tend to damage the samples. Optical coherence tomography (OCT) is a novel method to obtain high-resolution, and cross-sectional images of the automotive paints in a non-destructive, and high-speed manner. In this study, OCT was applied to image and analyze the automotive paint, using Scanning Electron Microscope (SEM) as reference. Eight automotive paint samples of different brands were examined. The images of multi-layer structures provided by OCT system with 5 μm depth resolution were consistent with ...

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    3. High efficiency for prostate biopsy qualification with full-field OCT after training

      High efficiency for prostate biopsy qualification with full-field OCT after training

      Full-field optical coherence tomography (FFOCT) offers a fast and non-destructive method of obtaining images of biological tissues at ultrahigh resolution, approaching traditional histological sections. In the context of prostate cancer diagnosis involving multiple biopsies, FFOCT could be used to validate the cores just after they are obtained in order to guide the number of biopsies to be performed. The aim of the study was to define and test a training protocol for efficient FFOCT prostate biopsy assessment. Three readers (a pathologist with previous experience with FFOCT, a pathologist new to FFOCT, and a urologist new to FFOCT) were trained to ...

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    4. Research Associate Position in OCT at the University of Maryland

      Research Associate Position in OCT at the University of Maryland

      Position description: A Postdoctoral Research Associate position is available at the University of Maryland, College Park. Research projects include intraoperative imaging of transplant kidney viability using OCT in collaboration with Georgetown University Medical Center, and development of automatic image processing algorithm to predict organ viability. Required expertise: Ph.D. in physics, electrical engineering, optical engineering, or biomedical/bioengineering. Hand-on experience on optical and electronic instrumentation and strong programming skills (Matlab, Labview, and C++). Prior research expertise on OCT and image processing. Application: Interested candidates should submit Curriculum vitae with a list of contact information of 3 references by email to ...

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    5. Analyzing the Evolution of Membrane Fouling via a Novel Method Based on 3D Optical Coherence Tomography Imaging

      Analyzing the Evolution of Membrane Fouling via a Novel Method Based on 3D Optical Coherence Tomography Imaging

      The development of novel tools for studying the fouling behavior during membrane processes is critical. This work explored optical coherence tomography (OCT) to quantitatively interpret the formation of a cake layer during a membrane process; the quantitative analysis was based on a novel image processing method that was able to precisely resolve the 3D structure of the cake layer on a micron scale. Fouling experiments were carried out with foulants having different physicochemical characteristics (silica nanoparticles and bentonite particles). The cake layers formed at a series of times were digitalized using the OCT-based characterization. The specific deposit (cake volume/membrane ...

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    6. Postdoctoral Fellow Position at the Advanced Ophthalmic Imaging Laboratory at Indian Universitiy

      Postdoctoral Fellow Position at the Advanced Ophthalmic Imaging Laboratory at Indian Universitiy

      The Advanced Ophthalmic Imaging Laboratory at Indiana University is looking to fill a postdoctoral fellow or research associateposition. The successful candidate will join a team of scientists and engineers that are developing the next-generation adaptive optics–optical coherence tomography (AO-OCT) system for studying structure and function of the living human retina at the cellular level. The system will open up exciting new directions to study both normal and pathological vision. The laboratory ( www.opt.indiana.edu/dtmiller/Index.aspx ) is part of the Indiana University Visual Optics Group, an active and well-funded community of vision scientists and engineers working in ...

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    7. Dynamic single gold nanoparticle visualization by clinical intracoronary optical coherence tomography

      Dynamic single gold nanoparticle visualization by clinical intracoronary optical coherence tomography

      The potential use of Gold Nanoparticles (GNPs) as contrast agents for clinical intracoronary frequency domain Optical Coherence Tomography (OCT) is here explored. The OCT contrast enhancement caused by GNPs of different sizes and morphologies has been systematically investigated and correlated with their optical properties. Among the different GNPs commercially available with plasmon resonances close to the operating wavelength of intracoronary OCT (1.3 µm), Gold Nanoshells (GNSs) have provided the best OCT contrast due to their largest scattering cross section at this wavelength. Clinical intracoronary OCT catheters are here demonstrated to be capable of three dimensional visualization and real-time tracking ...

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      Mentions: Fernando Alfonso
    8. Coin-Sized Scanner to Target Blindness

      Coin-Sized Scanner to Target Blindness

      A European group of scientists are working on the development of a breakthrough, compact, cost-effective retinal scanner that will play a key role in targeting the early diagnosis of retinal diseases that are worldwide leading causes of blindness. Funded by the Photonics PPP platform, OCTChip is set to revolutionise diagnosis of retinal diseases and prevent millions of cases of blindness. Diabetic Retinopathy accounts for the leading cause of blindness, with 200 million cases worldwide, and 60 million affected Europeans. With an ageing population, higher life expectancies and rising levels of diabetes, the number of cases preventable blindness are increasing. The ...

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    9. Optical module to extend any Fourier-domain optical coherence tomography system into a polarisation-sensitive system

      Optical module to extend any Fourier-domain optical coherence tomography system into a polarisation-sensitive system

      This article presents a theoretical study on an optical module (OM) that can be inserted between an object under investigation and a Fourier-domain optical coherence tomography system, transforming the latter into a polarisation-sensitive optical coherence tomography optical coherence tomography (OCT) system. The module consists of two electro-optic modulators, a Faraday rotator, a linear polariser and a quarter-wave plate. A detailed description on how the module can be used to extract both the net retardance and the fast axis orientation of a linear birefringent sample is presented. This is achieved by taking two sequential measurements for different values of retardance produced ...

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    10. Postdoctoral research position for Biomedical/Optics Engineer Scientist at Harvard Medical School and Wellman Center

      Postdoctoral research position for Biomedical/Optics Engineer Scientist at Harvard Medical School and Wellman Center

      The ear is a remarkable example of a biomechanical system. The goal of the OtoBiomechanics Group in the Otolaryngology Department at the Harvard Medical School is to use the OCT imaging modality combined with computational models and physiological measurements to understand the high sensitivity, high frequency selectivity and wide bandwidth of mammalian hearing. The project is well funded by grants from the NIH. Applications are invited for a post-doctoral research fellowship position to develop and build a state-of-the-art micro optical coherence topography (u-OCT) system to study cochlear and middle ear imaging and vibrometry in the laboratories of Profs. Sunil Puria ...

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    11. Post-Doc Position for Biomedical Engineer / Vision Scientist in the UC Davis EyePod - Small Animal Retinal Imaging Laboratory at University of California, Davis

      Post-Doc Position for Biomedical Engineer / Vision Scientist in the UC Davis EyePod - Small Animal Retinal Imaging Laboratory at University of California, Davis

      Applications are invited for post-doctoral research associate position in the UC Davis EyePod Small Animal Imaging Laboratory in the Department of Cell Biology and Human Anatomy at the UC Davis Main Campus. The goal of our research is to develop and translate the next generation in vivo cellular resolution multimodal retinal imaging instruments and data analysis tools and to apply them to disease mechanisms and therapeutic interventions that can be investigated in the eye. The ideal candidate will have strong skills in some combination of retinal/microscopic imaging modalities, including but not limited to adaptive optics (AO), OCT, SLO, multispectral ...

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    12. Associations between the Framingham Risk Score and coronary plaque characteristics as assessed by three-vessel optical coherence tomography

      Associations between the Framingham Risk Score and coronary plaque characteristics as assessed by three-vessel optical coherence tomography

      Objectives: This study sought to explore the association between the Framingham Risk Score (FRS) and coronary plaque characteristics assessed by optical coherence tomography (OCT) imaging. Background: Clinical prediction models are useful for identifying high-risk patients. However, coronary events often occur in individuals estimated to be at low risk. Methods: A total of 254 patients with coronary artery disease who underwent three-vessel OCT were divided into tertiles according to FRS. Nonculprit plaque characteristics were compared among the three groups. Results: A total of 663 plaques were analyzed. FRS was significantly associated with calcification [37% (low FRS) vs. 46% (intermediate FRS) vs ...

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    13. Perimeter Medical Imaging Receives FDA Clearance for OTISTM Optical Tissue Imaging System

      Perimeter Medical Imaging Receives FDA Clearance for OTISTM Optical Tissue Imaging System

      Perimeter Medical Imaging, Inc., an innovative medical imaging company whose mission is to revolutionize tissue removal surgery for surgeons and patients, today announced receipt of U.S. Food and Drug Administration (FDA) 510(k) clearance for its OTIS TM 1.0 Optical Coherence Tomography System. The OTIS™ provides high-resolution, real-time imaging of the periphery of excised tissue, enabling clinicians to visualize sub-surface structures up to 2 mm below the surface. These sub-surface structures would otherwise not be evident until days – and often weeks – later when conventional histology slides are available for review. Dr. Ted James, Medical Director of Skin & Soft ...

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    14. Detection of retinal blood vessel changes in multiple sclerosis with optical coherence tomography

      Detection of retinal blood vessel changes in multiple sclerosis with optical coherence tomography

      Although retinal vasculitis is common in multiple sclerosis (MS), it is not known if MS is associated with quantitative abnormalities in retinal blood vessels (BVs). Optical coherence tomography (OCT) is suitable for examining the integrity of the anterior visual pathways in MS. In this paper we have compared the size and number of retinal blood vessels in patients with MS, with and without a history of optic neuritis (ON), and control subjects from the cross-sectional retinal images from OCT. Blood vessel diameter (BVD), blood vessel number (BVN), and retinal nerve fiber layer thickness (RNFL T ) were extracted from OCT images ...

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    15. Medical Marvel: Duke’s GPU-Powered Imaging Wins $150,000 Global Impact Award

      Medical Marvel: Duke’s GPU-Powered Imaging Wins $150,000 Global Impact Award

      Duke University researchers have received NVIDIA’s $150,000 Global Impact Award for their work using GPU-powered imaging techniques that give surgeons a 3D, stereoscopic live feed while performing highly sensitive ocular microsurgery. Nearly 30 applications from 13 nations were submitted for the annual award, which recognizes researchers using NVIDIA technology for groundbreaking work that addresses social, humanitarian and environmental problems. The Duke team, led by engineering professor Joseph Izatt , are using GPUs to transform how optical microsurgery is conducted. State-of-the-art microscopes produce 3D images of the eye every few microseconds to give surgeons immediate feedback during operations. Global Impact ...

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    16. Postdoctoral Research Fellowship in ophthalmic adaptive optics optical coherence tomography imaging at Duke University

      Postdoctoral Research Fellowship in ophthalmic adaptive optics optical coherence tomography imaging at Duke University

      Immediate opening at Duke University Biomedical Engineering Department for a Postdoctoral Research Associate interested in development of novel fast and high-resolution ophthalmic adaptive optics (AO) and Optical Coherence Tomography (OCT) imaging systems. Postdoc will be supervised by Prof. Joseph A. Izatt ( http://bme.duke.edu/faculty/joseph-izatt ) in collaboration with Prof. Sina Farsiu ( http://people.duke.edu/~sf59/ ). Multiple previous PhD students and postdocs from this team are now faculty members in top universities around the world. Requirement: PhD in EE, BME, or CS. The candidate must have a demonstrated strong background in optical design and photonics imaging as evidenced ...

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    17. Optical teardown of a Kindle Paperwhite display by OCT.

      Optical teardown of a Kindle Paperwhite display by OCT.

      An optical teardown, or reverse engineering, of an Amazon Kindle Paperwhite electrophoretic display was performed by Optical Coherence Tomography at 1060 nm. The display incorporates an optical diffuser, lightguide and scattering layers for white light illumination, capacitive touch sensing, and an electrophoretic display. All these layers can be imaged by OCT as well as the thin film transistor array on the back side for driving the pixels. Phase sensitive OCT is used to measure motion of the pigment particles as the display changes between black and white.

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    18. Two Imaging Catheters Unite to Better Detect Dangerous Plaques in Arteries

      Two Imaging Catheters Unite to Better Detect Dangerous Plaques in Arteries

      Collaboration between two National Institute of Biomedical Imaging and Bioengineering (NIBIB)-funded labs has revealed a promising new method for identifying atherosclerotic plaques, the encased deposits in arteries that restrict blood flow and can lead to heart attack or stroke. The technique combines two different types of imaging, allowing for an unprecedented combination of depth and detail. The hybrid technology will provide doctors with a better diagnostic tool for identifying particularly problematic plaques. Heart disease is the leading cause of death worldwide. The majority of deaths from heart disease are caused by the rupture of a plaque lining an artery ...

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    19. NinePoint Medical Announces FDA 510(k) Clearance of a Real-Time Targeting Feature for the NvisionVLE® Imaging System and the First Clinical Cases in the U.S.

      NinePoint Medical Announces FDA 510(k) Clearance of a Real-Time Targeting Feature for the NvisionVLE® Imaging System and the First Clinical Cases in the U.S.

      NinePoint Medical, Inc., a transformative medical device company pioneering the use of a real-time imaging platform for gastrointestinal applications, announced today that it has received U.S. Food and Drug Administration (FDA) 510(k) clearance to market its Real-time Targeting™ feature for its flagship product, the NvisionVLE ® Imaging System. In addition, the first procedures with this new system were performed at Beth Israel Deaconess Medical Center in Boston, Massachusetts. The NvisionVLE Imaging System employs proprietary Optical Coherence Tomography (OCT) technology allowing physicians to perform a Volumetric Laser Endomicroscopy (VLE) procedure that produces real-time, high-resolution cross-sectional images. This system enables gastroenterologists ...

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    20. Abbott Agrees to Buy St. Jude in $25 Billion Deal

      Abbott Agrees to Buy St. Jude in $25 Billion Deal

      Abbott Laboratories agreed to acquire St. Jude Medical Inc. in a cash-and-stock deal valued at $25 billion that would create one of the leading makers of heart-related devices. Under the deal, Abbott agreed to swap $46.75 in cash and 0.8708 shares for each St. Jude share. The offer values each St. Jude share at about $85, representing a 37% premium to the stock’s closing price Wednesday. Shares of Abbott fell 7% to $40.60 in early trading, while St. Jude rose 25% to $77.70. The companies said the deal merges St. Jude’s strong positions in ...

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      Mentions: St. Jude Medical
    1-20 of 20
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