1. OCT-Angiography in Geographic Atrophy

    OCT-Angiography in Geographic Atrophy

    Geographic atrophy (GA) represents the nonexudative late stage of age-related macular degeneration (AMD) and constitutes a leading cause of legal blindness in the developed world. It is characterized by areas of loss of outer retinal layers including photoreceptors, degeneration of the retinal pigment epithelium, and rarefication of the choriocapillaris. As all three layers are functionally connected, the precise temporal sequence and relative contribution of these layers towards the development and progression of GA is unclear. The advent of optical coherence tomography angiography (OCT-A) has allowed for three-dimensional visualization of retinal blood flow. Using OCT-A, recent studies have demonstrated that choriocapillaris ...

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