1. Imaging artifacts in widefield optical coherence tomography angiography in patients with retinitis pigmentosa

    Imaging artifacts in widefield optical coherence tomography angiography in patients with retinitis pigmentosa

    Purpose : Optical coherence tomography angiography (OCTA) provides high-resolution images of retinal vasculature whereby vessel density (VD) can be used as an outcome marker. VD is diminished in patients with retinitis pigmentosa (RP) but its quantification can be confounded by imaging artifacts. In this retrospective study, we investigate artifacts that may affect the clinical application of widefield OCTA (WF-OCTA) in patients with RP. Methods : University of Kentucky IRB (#48463) approved retrospective analysis of WF-OCTA images from 33 subjects with a diagnosis of RP and 12x12mm OCTA imaging (Plex Elite 9000, Zeiss, Dublin, CA). Images form the eye with higher signal strength ...

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