1. Optical coherence tomography assessment of macrophages accumulation in non-ST-segment elevation acute coronary syndromes

    Optical coherence tomography assessment of macrophages accumulation in non-ST-segment elevation acute coronary syndromes

    Aims To investigate in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) the prevalence and the features of optical coherence tomography (OCT)-detected macrophages accumulation in culprit plaques as compared with nonculprit plaques (NCP). Methods The study is a post-hoc analysis of a prospective study aimed at evaluating the relationship between aortic inflammation as assessed by 18 F-fluorodeoxyglucose-PET and features of coronary plaque vulnerability as assessed by OCT. We enrolled 32 patients with first NSTE-ACS who successfully underwent three-vessel OCT. Results The median age was 65 (54–72) years and 27 patients (84%) were men. Culprit plaques were clinically defined ...

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