1. A Cross-sectional Optical Coherence Tomography Study in Patients on Taxane-based Therapy and A Case Report with the Literature Review

    A Cross-sectional Optical Coherence Tomography Study in Patients on Taxane-based Therapy and A Case Report with the Literature Review

    Purpose: To evaluate the characteristics of macular retinal and subfoveal choroidal changes in patients already on taxane-based therapy by the help of spectral domain optical coherence tomograpy (SD-OCT) and determine the incidence of taxane- related cystoid macular edema (CME). Materials and Methods: In this cross-sectional case-control study, 202 patients who received taxane-based therapy due to treatment of various cancer and age and sex-matched 200 healthy control subjects were examined. Only patients who received at least 4 cycles of taxane-based therapy were taken into consideration for the taxane group. Taxane-based therapy was further divided into two subgroups; paclitaxel group (149 patients ...

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