1. Visible light optical coherence tomography angiography (vis-OCTA) facilitates local microvascular oximetry in the human retina

    Visible light optical coherence tomography angiography (vis-OCTA) facilitates local microvascular oximetry in the human retina

    We report herein the first visible light optical coherence tomography angiography (vis-OCTA) for human retinal imaging. Compared to the existing vis-OCT systems, we devised a spectrometer with a narrower bandwidth to increase the spectral power density for OCTA imaging, while retaining the major spectral contrast in the blood. We achieved a 100 kHz A-line rate, the fastest acquisition speed reported so far for human retinal vis-OCT. We rigorously optimized the imaging protocol such that a single acquisition took < 6 seconds with a field of view (FOV) of 3×7.8 mm 2 . The angiography enables accurate localization of microvasculature down ...

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