1. Validation of a Compensation Strategy used to Detect Choriocapillaris Flow Deficits Under Drusen with Swept Source OCT Angiography

    Validation of a Compensation Strategy used to Detect Choriocapillaris Flow Deficits Under Drusen with Swept Source OCT Angiography

    Purpose A compensation strategy that was developed to measure the choriocapillaris (CC) flow deficits (FDs) under drusen was tested in eyes with large drusen from age-related macular degeneration (AMD) before and after the drusen spontaneously resolved without evidence of disease progression. Design Prospective, observational consecutive case series. Methods Patients with AMD were enrolled in a prospective SS-OCT imaging study (PLEX® Elite 9000, Carl Zeiss Meditec). Consecutive eyes with large drusen were followed, and eyes that underwent spontaneous collapse of drusen without evidence of disease progression were identified retrospectively. The drusen-resolved regions were manually outlined. CC FDs were measured using a ...

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