1. Use of Optical Coherence Tomography Retinal Thickness Deviation Map for Hydroxychloroquine Retinopathy Screening

    Use of Optical Coherence Tomography Retinal Thickness Deviation Map for Hydroxychloroquine Retinopathy Screening

    Objective To investigate the use of a retinal thickness deviation map generated from swept-source optical coherence tomography (SS-OCT) images for hydroxychloroquine (HCQ) retinopathy screening. Design Retrospective cohort study Subjects This study included 1,192 Korean patients with a history of HCQ treatment—881 (1,723 eyes) in the discovery set and 311 (591 eyes) in the validation set. Patients were screened for retinal toxicity using SS-OCT, fundus autofluorescence, and standard automated perimetry. Methods According to the 2016 American Academy of Ophthalmology guidelines, HCQ retinopathy was diagnosed by the presence of abnormalities on ≥1 objective structural tests alongside corresponding visual field ...

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