1. Vitreous Findings by Handheld Spectral Domain Optical Coherence Tomography Correlate with Retinopathy of Prematurity Severity

    Vitreous Findings by Handheld Spectral Domain Optical Coherence Tomography Correlate with Retinopathy of Prematurity Severity

    Objective To evaluate the association between retinopathy of prematurity and vitreous findings in premature infants detected by handheld spectral-domain optical coherence tomography. Design Prospective, observational cohort study. Participants Consecutive sample of 92 premature infants requiring retinopathy of prematurity screening at two academic neonatal intensive care units, between July 2015 and March 2018. Methods Infants underwent handheld spectral domain optical coherence tomography at the time of routine retinopathy of prematurity examinations. Two masked, trained graders analyzed right eye vitreoretinal findings including semi-automated quantification of punctate hyperreflective vitreous opacities within 5 foveal/parafoveal B-scans (Vitreous Opacity Ratio). Main Outcome Measures: Excluding post-treatment ...

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