1. Analysis of in vitro and in vivo bidirectional flow velocities by phase-resolved doppler fourier-domain OCT

    Fourier-domain Optical Coherence Tomography (FD-OCT) is a non-invasive imaging technique which allows the in vivo examination of subsurface tissue. Besides the structural imaging, FD-OCT is capable to measure blood flow velocities. This method is referred to as phase-resolved Doppler FD-OCT and often used in small retinal vessels (diameters about 100 μm) with low blood flow velocities. In this study, we present a FD-OCT system with a spectrum read-out rate of 11.88k Hz showing the ability to assess velocity profiles in the in vivo mouse model with blood vessels up to a diameter of 300 μm. Before realization of the ...
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