1. Extended imaging depth of en-face optical coherence tomography based on fast measurement of a reflection matrix by wide-field heterodyne detection

    Extended imaging depth of en-face optical coherence tomography based on fast measurement of a reflection matrix by wide-field heterodyne detection

    Multiple light scattering in biomedical tissue limits the penetration depth of optical imaging systems such as optical coherence tomography. To increase the imaging depth in scattering media, a computational method based on coherent reflection matrix measurement has been developed using low coherence interferometry. The complex reflection matrix is obtained via point-by-point scanning followed by a phase-shifting method; then singular value decomposition is used to retrieve the singly back-scattered light. However, the in vivo application of the current reported method is limited due to the slow acquisition speed of the matrix. In this Letter, a wide-field heterodyne-detection method is adopted to ...

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