1. Angular compounding for speckle reduction in optical coherence tomography using geometric image registration algorithm and digital focusing

    Angular compounding for speckle reduction in optical coherence tomography using geometric image registration algorithm and digital focusing

    Optical coherence tomography (OCT) suffers from speckle noise due to the high spatial coherence of the utilized light source, leading to significant reductions in image quality and diagnostic capabilities. In the past, angular compounding techniques have been applied to suppress speckle noise. However, existing image registration methods usually guarantee pure angular compounding only within a relatively small field of view in the focal region, but produce spatial averaging in the other regions, resulting in resolution loss and image blur. This work develops an image registration model to correctly localize the real-space location of every pixel in an OCT image, for ...

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