1. Automated segmentation of the optic disc margin in 3-D optical coherence tomography images using a graph-theoretic approach

    Automated segmentation of the optic disc margin in 3-D optical coherence tomography images using a graph-theoretic approach

    The optic disc margin is of interest due to its use for detecting and managing glaucoma. We developed a method for segmenting the optic disc margin of the optic nerve head (ONH) in spectral-domain optical coherence tomography (OCT) images using a graph-theoretic approach. A small number of slices surrounding the Bruch's membrane opening (BMO) plane was taken and used for creating planar 2-D projection images. An edge-based cost function - more specifically, a signed edge-based term favoring a dark-to-bright transition in the vertical direction of polar projection images (corresponding to the radial direction in Cartesian coordinates) - was obtained. Information from ...

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