1. Real-time, non-contact, cellular imaging and angiography of human cornea and limbus with common-path Full-field/SD OCT

    Real-time, non-contact, cellular imaging and angiography of human cornea and limbus with common-path Full-field/SD OCT

    In today’s clinics, a cellular-resolution view of the cornea can be achieved only with an in vivo confocal microscope (IVCM) in contact with the eye. Here, we present a common-path Full-field/Spectral-domain OCT microscope (FF/SD OCT), which, for the first time, enables cell-detail imaging of the entire ocular surface (central and peripheral cornea, limbus, sclera, tear film) without contact and in real time. The device, that has been successfully tested in human subjects, is now ready for direct implementation in clinical research. Real-time performance is achieved through rapid axial eye tracking and simultaneous defocusing correction. Images, extracted from ...

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