1. Microvascular retinal changes in pre-clinical diabetic retinopathy as detected by optical coherence tomographic angiography

    Microvascular retinal changes in pre-clinical diabetic retinopathy as detected by optical coherence tomographic angiography

    Purpose To investigate microvascular abnormalities in diabetic patients without conventional clinical signs of diabetic retinopathy (DR). Methods In this cross-sectional observational cohort study, the study group included randomly chosen participants of a community-based cohort with diabetes type 2 without DR, and the control group consisted of non-diabetic individuals from a population-based study. All participants underwent optical coherence tomographic angiography (OCTA). Results Upon OCTA, 118 (40.4%) eyes of the study group ( n  = 292 eyes) showed microvascular abnormalities including foveal avascular zone erosion (95 (32.5%) eyes), non-perfusion areas in the superficial and deep retinal layers (39 (13.4%) eyes and ...

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