1. A metrological approach to the analysis of choroidal thickness by optical coherence tomography 3D scans in myopia research

    A metrological approach to the analysis of choroidal thickness by optical coherence tomography 3D scans in myopia research

    n myopia research, changes of choroidal thickness in response to optically induced signals serve as predictor for changes in axial length that might be correlated with myopia progression. Optical coherence tomography (OCT) provides a tool for imaging the choroid, however, with certain difficulties because of a limited visibility of the scleral-choroidal interface. Considering the previously reported effect sizes of thickness change in human myopia research, this study investigated the repeatability of automated 3D choroidal segmentation across the macular area of 6 × 6 mm 2 . Fifteen subjects underwent nine volume scans in two OCT devices with analysis of the 95% interval ...

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