1. Capillary Refill—The Key to Assessing Dermal Capillary Capacity and Pathology in Optical Coherence Tomography Angiography

    Capillary Refill—The Key to Assessing Dermal Capillary Capacity and Pathology in Optical Coherence Tomography Angiography

    Background/Objectives: Standard optical coherence tomography angiography (OCTA) has been limited to imaging blood vessels actively undergoing perfusion, providing a temporary picture of surface microvasculature. Capillary perfusion in the skin is dynamic and changes in response to the surrounding tissue's respiratory, nutritional, and thermoregulatory needs. Hence, OCTA often represents a given perfusion state without depicting the actual extent of the vascular network. Here we present a method for obtaining a more accurate anatomic representation of the surface capillary network in human skin using OCTA, along with proposing a new parameter, the Relative Capillary Capacity (RCC), a quantifiable proxy for ...

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