1. Effects of intravitreal conbercept before panretinal photocoagulation on lipid exudates in diabetic macular documented by optical coherence tomography

    Effects of intravitreal conbercept before panretinal photocoagulation on lipid exudates in diabetic macular documented by optical coherence tomography

    Aims: To evaluate the effects of intravitreal Conbercept (IVC) as adjunctive treatments before PRP to decrease hyperreflective dots (HRDs) in Chinese PDR patients. Methods: Fifty-nine enrolled patients were categorized into 2 groups: single dose IVC (0.5 mg/0.05 mL) 1wk before PRP (Plus group) or PRP only (PRP group). Six months later, we measured the best corrected visual acuity (BCVA), central macula thickness (CMT) by OCT and counted the number of HRDs in different retina layers. Results: The average CMT significantly decreased in Plus group but increased in PRP group. The average BCVA in the Plus group was ...

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