Quantifying the effect of milli-molar glucose concentration on thickness of rabbit cornea with optical coherence tomography

Entities Mentioned

• University of Houston
• Kirill V. Larin
• Mohamad G. Ghosn

1. The cornea contributes about 65% of the eye's ability to refract light. Thus, any fluctuation in corneal thickness can cause noticeable changes in vision. The presence of glucose molecules induces a driving force for water to leave the collagen fibrils in the cornea due to the concentration gradient created, thus changing its thickness. In this study, the effect of various milli-molar glucose concentrations on corneal thickness was explored using Optical Coherence Tomography. Whole rabbit eyes were placed in a specially designed dish while immersed in saline to ensure proper hydration of the eye. The cornea was imaged for 10 minutes. ... (Read Full Article)

   Bookmark or Share this article

   
   

   Related Articles

   • Comparison of Central Corneal Thickness using Anterior Segment ...
   • also categorized in Ophthalmology
   • Full-field optical coherence tomography (oct) and early alterations in chloroplast morphology
   • also published in SPIE Digital Library
   • Concentration effect on the diffusion of glucose in ocular tissues
   • also written by Mohamad G. Ghosn
   • Simultaneous imaging of human cone mosaic with adaptive optics enhanced scanning laser ophthalmoscopy and high-speed transversal scanning optical coherence tomography
   • also categorized in Ophthalmology
   • Effect of temperature on permeation of low-density lipoprotein particles through human carotid artery tissues
   • also written by Mohamad G. Ghosn

   • Optic neuritis and multiple sclerosis.
   • also categorized in Ophthalmology
   • Monitoring of glucose permeability in monkey skin in vivo using Optical Coherence Tomography
   • also written by Mohamad G. Ghosn
   • Incision construction, architecture fight infection
   • also categorized in Ophthalmology
   • Laser-Based Gadget Finds the Bends for Astronauts, Navy Seals
   • also mentions Kirill V. Larin
   • Dynamic full-range Fourier-domain optical coherence tomography using sinusoidal phase-modulating interferometry
   • also published in SPIE Digital Library

Login to comment.