1. Optical Coherence Tomography Monitoring in a Patient With Retinoblastoma

    Optical Coherence Tomography Monitoring in a Patient With Retinoblastoma

    A 17-month-old girl with group B retinoblastoma in her right eye developed recurrence of a parafoveal tumor ( Figure , A) after 6 cycles of intravenous chemotherapy. Despite treatment with indocyanine green–enhanced transpupillary thermotherapy, optical coherence tomography (vertical orientation) demonstrated continued tumor growth toward the foveola. The patient was subsequently treated with 2 cycles of intra-arterial chemotherapy, after which complete tumor regression to a flat scar was documented clinically and by optical coherence tomography (vertical orientation) ( Figure , B). The foveola remained intact. Optical coherence tomography may be a helpful tool in the documentation of retinoblastoma response, particularly in patients with small ...

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