1. Characterization and oxygen saturation study of human retinal blood vessels evaluated by spectroscopic Optical Coherence Tomography Angiography

    Characterization and oxygen saturation study of human retinal blood vessels evaluated by spectroscopic Optical Coherence Tomography Angiography

    Optical coherence tomography is non-invasive diagnostic technique for performing high resolution (~µm) cross sectional imaging. In this article, we demonstrate characterization and oxygen saturation studies of human retinal blood vessels with Principal Component Analysis (PCA) based Spectroscopic Optical Coherence Tomography-based Angiography. A Fourier Domain Mode-Locked laser having an axial imaging resolution of ~7.5 µm, with an A-scan sweep rate of 1.7 MHz and centre wavelength of 1060 nm, was utilized as an OCT source. PCA has been used in conjunction with a scanning Short Time Fourier Transform, procedure to isolate the probable amount of oxygenated and deoxygenated haemoglobin ...

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