1. Are Dilated Fundus Exams Needed for Optical Coherence Tomography–Guided Re-treatment of Exudative Age-Related Macular Degeneration?

    Are Dilated Fundus Exams Needed for Optical Coherence Tomography–Guided Re-treatment of Exudative Age-Related Macular Degeneration?

    Purpose To determine whether presence of macular hemorrhage on dilated fundus exam (DFE) or fundus photography influences vision outcomes with optical coherence tomography (OCT)-guided pro re nata (PRN) ranibizumab (RBZ) re-treatment in patients with neovascular age-related macular degeneration (nAMD), we investigated whether hemorrhage without OCT-detectable fluid impacted vision outcomes. Design Post hoc analysis of prospectively collected data from the 24-month phase III HARBOR trial (NCT00891735). Participants This post hoc analysis examined 1097 patients from the intention-to-treat population of HARBOR. Methods DFE and fundus photography were evaluated for hemorrhage, and spectral domain (SD)-OCT images from HARBOR participants were analyzed ...

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