1. Nodular skin lesions: correlation of reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) features

    Nodular skin lesions: correlation of reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) features

    Nodular lesions have a common clinical appearance but very different prognostic implications. The differential diagnosis between malignant and benign nodular lesions is a challenge in everyday clinical practice. The malignant melanoma (MM) nodular variant expresses a vertical phase of growth and often has relatively high Breslow indexes 1,2 , so a timely correct diagnosis is crucial for correct lesion management. Conversely, non‐melanoma skin cancer (NMSC) rarely impacts on patient mortality and is most frequently observed in the form of a basal cell carcinoma (BCC), a locally aggressive, low‐grade neoplasia, prevalent among sun‐damaged elders 3,4 .

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