1. Epithelial tissue thickness improves optical coherence tomography’s ability in detecting oral cancer

    Epithelial tissue thickness improves optical coherence tomography’s ability in detecting oral cancer

    Background OCT is a non-invasive imaging technique that enables the measurement of epithelial thickness and architectural changes, which can help in the diagnosis of pre-cancerous and cancerous lesions. The purpose of the study was to assess whether epithelial tissue thickness improves optical coherence tomography’s ability in detecting oral cancer. Patients and Methods Surgically resected oral margins from 60 patients diagnosed with oral squamous cell carcinoma were subjected to OCT. Three OCT measurements (immediate, 1 hour and 24 hours post-resection) were conducted per resected tissue specimen to look at the effect of saline and formalin on the specimen and its ...

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