1. Angiography and optical coherence tomography assessment of the drug-coated balloon ESSENTIAL for the treatment of in-stent restenosis

    Angiography and optical coherence tomography assessment of the drug-coated balloon ESSENTIAL for the treatment of in-stent restenosis

    Objectives This study sought to assess the efficacy of the drug-coated balloon (DCB) ESSENTIAL for the treatment of in-stent restenosis (ISR). Background DCBs have proven a valid therapeutic option for the management of ISR in several clinical trials, yet no class effect can be claimed. Accordingly, every new DCB model has to be individually evaluated through clinical studies. Methods This is a prospective, multicenter study including consecutive patients undergoing percutaneous coronary intervention for ISR with the ESSENTIAL DCB. A 6-month quantitative coronary angiography (QCA)/optical coherence tomography (OCT) follow-up was scheduled. The primary endpoint was OCT-derived in-segment maximal area stenosis ...

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