1. Optical Coherence Tomography/Fluorescence Imaging: Fiber assembly enables efficient multimodal endoscopy

    Optical Coherence Tomography/Fluorescence Imaging: Fiber assembly enables efficient multimodal endoscopy

    While optical coherence tomography (OCT) provides structural contrast with a resolution on the order of tens of microns, for some applications this information is, in some contexts, insufficient to provide a definitive diagnostic. To mitigate this limitation, OCT has been used in conjunction with fluorescence imaging or spectroscopy for detection of molecular content in tissues. The combination of OCT and fluorescence has been used for a variety of applications, most notably to study atherosclerotic plaque in cardiology, 1 to visualize the fine vascular network in pulmonology (for which autofluorescence is used), 2 and for cancer imaging. 3

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