1. Choroidal Hyperreflective Foci A Novel Spectral Domain Optical Coherence Tomography Biomarker in Eyes With Diabetic Macular Edema

    Choroidal Hyperreflective Foci A Novel Spectral Domain Optical Coherence Tomography Biomarker in Eyes With Diabetic Macular Edema

    Purpose: The aim of this study was to examine the hyperreflective dots seen in choroid on spectral domain optical coherence tomography ( SDOCT ) in eyes with diabetic macular edema (DME) and correlate it with visual acuity. Design: Consecutive, cross-sectional case series of patients with DME between January 2017 and December 2017. Methods: Eyes with DME having central foveal thickness ≥250 μm were included. SDOCT was performed using Spectralis system (Heidelberg Engineering, Germany). Hyperreflective choroidal foci (HCF) were defined as well-circumscribed dots within choroid having reflectivity equal to or higher than adjacent retinal pigment epithelium. HCF were counted manually within 1500 μm ...

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