1. Dermoscopy, Optical Coherence Tomography, and Histological Correlation of Pseudoxanthoma Elasticum

    Dermoscopy, Optical Coherence Tomography, and Histological Correlation of Pseudoxanthoma Elasticum

    We propose the case of a 17-year-old female patient with multiple, soft, yellowish papules symmetrically distributed on the neck ( Figure 1A ). Dermoscopy showed a yellowish orange area associated with reddish and whitish areas [ 1 ] ( Figure 1B ). Optical coherence tomography (OCT) revealed normal epidermis associated with clusters of horizontally oriented dermal aggregates with peripheral clefts ( Figure 1C ). A biopsy was performed in the same site of previous noninvasive imaging techniques. Histology disclosed the presence of altered elastic fibers in the upper and reticular dermis with extension to the papillary dermis stained with hematoxylin and eosin ( Figure 1D ). Pseudoxanthoma elasticum (PXE) is ...

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