1. Interspecies Variation of Outer Retina and Choriocapillaris Imaged With Optical Coherence Tomography

    Interspecies Variation of Outer Retina and Choriocapillaris Imaged With Optical Coherence Tomography

    Purpose : The purpose of this study is to assess with spectral-domain optical coherence tomography (OCT) the interspecies variation of outer retinal morphology and identification of choriocapillaris in four research animal species. Methods : Spectralis HRA+OCT images acquired from locations dorsal, central, and ventral to the optic disc in healthy, anesthetized animals were evaluated by two independent readers. First, the number of OCT B-scans on which a choriocapillaris layer could clearly be identified was determined and quantified, and B-scans were correlated with histology. Second, B-scans demonstrating the highest number of discernable individual outer retinal bands (ORBs) were defined as ideal presentation ...

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